SELENIUM TAB 100'S (GNC)

Selenium, when administered orally in tablet form, primarily exerts its effects through its incorporation into selenoproteins, which are essential for various physiological processes. One of the key mechanisms of action is its role as a cofactor for antioxidant enzymes, particularly glutathione peroxidase (GPx). Selenium facilitates the activity of GPx, which helps protect cells from oxidative damage by reducing hydrogen peroxide and lipid hydroperoxides to water and fatty acids, respectively. This antioxidant function is crucial in maintaining cellular homeostasis and preventing oxidative stress-related damage. Additionally, selenium-containing proteins are involved in thyroid hormone metabolism, immune function, and DNA synthesis, contributing to the overall biological effects of selenium supplementation. The incorporation of selenium into these specific proteins allows it to influence cellular signaling pathways and modulate various cellular processes.

Antioxidant/Mineral Supplement.

Tablet

The following are the uses of Selenium Tablet:

• Used for treating selenium deficiency, ensuring optimal levels of this essential mineral in the body.
• Used for its antioxidant properties, protecting cells from damage caused by free radicals.
• Used to support thyroid health, as selenium plays a crucial role in thyroid hormone production.
• Used in maintaining a healthy immune system, enhancing its response to infections.
• Used for skin health, aiding in various skin conditions and promoting overall skin wellness.
• Used as a potential cancer prevention supplement, although more research is needed in this area.
• Used to support heart health by reducing oxidative stress and inflammation.

In the case of an overdose of Selenium Tablets, it is important to recognize the potential symptoms and take appropriate action. Overdosing on Selenium can lead to gastrointestinal issues such as nausea, vomiting, and diarrhea. Additionally, neurological symptoms like fatigue, irritability, and nervous system disturbances may occur. If an overdose is suspected, seeking medical advice promptly is recommended to ensure proper evaluation and management of any adverse effects.

In the case of a missed dose of Selenium Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare professional for guidance on how to safely resume your medication regimen. Always keep a consistent dosing routine to ensure the medication's effectiveness.

To take the Selenium Tablet, swallow the tablet whole with a full glass of water, preferably with or after a meal, as directed by your healthcare professional.

Following are the conditions/situations to avoid using Selenium Tablet:

• Allergic reactions • Should not be taken if you have a known allergy or sensitivity to selenium or any other ingredients in the tablet.
• Thyroid issues • Not recommended for individuals with untreated or uncontrolled thyroid problems.
• Selenium supplementation • Avoid if you are already receiving adequate selenium from your diet or other supplements.
• Skin conditions • Selenium tablets should not be used topically on open wounds, burns, or severely compromised skin.
• Overexposure • Do not take if you have been exposed to high levels of selenium from other sources.
• Pre-existing medical conditions • Not suitable for individuals with certain medical conditions like hemochromatosis or thalassemia.
• Pediatric use • Selenium tablets are not recommended for children without medical advice.
• Pregnancy and breastfeeding • Should be used with caution or as advised by a healthcare professional during pregnancy and breastfeeding.

The side effects of Selenium Tablet may include:

• Gastrointestinal issues such as nausea, vomiting, and diarrhea.
• Skin reactions like rashes, hives, or itching.
• Hair loss or brittleness.
• Metallic taste in the mouth.
• Fatigue and general weakness.
• Joint pain and muscle aches.
• Neurological symptoms such as numbness, tingling, or confusion in severe cases.
• Long-term use at high doses may lead to selenium toxicity, causing garlic-like breath, fever, liver issues, and neurological problems.

Following are the precautions and warnings for Selenium Tablet:

• Not suitable for individuals with a known allergy to Selenium or any of its ingredients.
• Should be used with caution in patients with a history of gastrointestinal issues, as it may cause nausea, vomiting, or diarrhea.
• Patients with a history of skin reactions should exercise caution, as Selenium can potentially cause skin rashes or irritation.
• Not recommended for long-term use without medical supervision, as excessive Selenium intake can lead to toxicity.
• Those with a history of thyroid disorders should consult a healthcare professional before use, as Selenium may affect thyroid function.
• Should be kept out of reach of children, as accidental ingestion may be harmful.
• Individuals with diabetes should monitor their blood sugar levels as Selenium may affect glucose metabolism.

Following are the drug interactions for Selenium Tablet:

• Selenium may decrease the absorption of chemotherapy drugs like Cisplatin, potentially reducing their effectiveness.
• Concomitant use with corticosteroids can lead to decreased Selenium levels in the body.
• May reduce the efficacy of oral contraceptives, potentially affecting birth control.
• Antacids containing aluminum may decrease Selenium absorption when taken together.
• Warfarin and other blood thinners may have their effects altered, as Selenium can affect blood clotting mechanisms.
• Insulin metabolism can be influenced by Selenium, so monitoring is required when used with diabetes medications.
• Certain supplements like zinc and vitamin C may interact with Selenium, affecting absorption and utilization.

Following are the food interactions for Selenium Tablet:

• Avoid excessive consumption of Brazil nuts as they are naturally rich in Selenium, and excessive intake can lead to Selenium toxicity.
• Selenium-rich foods like seafood (tuna, shrimp), organ meats, and whole grains can be consumed but in moderation to prevent exceeding the recommended daily intake.
• Garlic, when taken in large amounts, may decrease Selenium levels in the body, so balance is key.
• Selenium absorption can be enhanced when consumed with foods containing Sulphur compounds, such as cruciferous vegetables (broccoli, cauliflower).
• Avoid high-dose Selenium supplements if you regularly consume Selenium-rich foods to prevent exceeding safe levels.
• Selenium levels can be affected by processing and cooking methods, with boiling potentially reducing Selenium content in foods.
• Some food sources of Selenium, like certain mushrooms, should be cooked to reduce potential toxin levels.
• Selenium absorption may be influenced by the overall diet, with a well-balanced diet promoting better absorption.

Selenium Tablets should be stored in a cool, dry area, ideally at room temperature, protected from direct sunlight and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. Avoid placing them in bathrooms or near heat sources like ovens or radiators, as temperature fluctuations can impact the tablets' quality. Dispose of any unused or expired tablets carefully; do not flush them down the toilet or pour them into drains. Consult your pharmacist for appropriate disposal methods, and ensure the medication is kept away from children to prevent accidental ingestion. Proper storage and disposal are crucial for maintaining the effectiveness and safety of Selenium Tablets.

Following are the quick tips for Selenium Tablet:

• Take the tablet as directed by your doctor, usually once daily.
• Consume the tablet with a full glass of water, preferably with meals.
• Do not crush or chew the tablet; swallow it whole for best effect.
• Maintain a consistent routine by taking it at the same time each day.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Inform your doctor about all medications you're taking to avoid interactions.
• Regularly monitor your selenium levels as directed by your healthcare provider.