Senalax 120ml Syrup

Sennosides A and B, found in Sennosides A and B Syrup/Suspension, act as stimulant laxatives by directly affecting the intestinal wall. They are not absorbed in the small intestine and reach the colon, where they are metabolized by the intestinal bacteria to produce active metabolites. These metabolites, namely rheinanthrone and sennidien, stimulate intestinal peristalsis by binding to and activating prostaglandin receptors, particularly PGE2 receptors, in the intestinal mucosa. This activation increases intestinal motility, leading to the promotion of bowel movements and the softening of stools. The combined effect of these mechanisms helps to relieve constipation.

Laxative (stimulant)

Suspension

The following are the uses of Sennosides A and B Syrup/Suspension:

• Used for short-term relief of constipation, softening stools, and making bowel movements easier.
• Used for clearing the bowels before surgical procedures or certain medical tests.
• Used for treating occasional constipation related to travel or changes in routine.
• Used for improving bowel function during periods of limited mobility or recovery from illness.
• Used for providing gentle relief from constipation associated with pregnancy or post-partum care.
• Used for helping to restore bowel regularity in elderly patients or those with chronic constipation issues.
• Used for preparing the colon before colonoscopy procedures, ensuring better visibility during the exam.
• Used for promoting bowel movement in patients with hemorrhoids or post-hemorrhoidectomy care.

In the case of an overdose of Sennosides A and B Syrup/Suspension, symptoms may include severe abdominal pain, diarrhea, and electrolyte imbalances. Prompt medical attention is necessary, and individuals should be monitored for potential complications. Treatment involves managing symptoms, rehydration, and correcting electrolyte disturbances. It is important to seek medical advice regarding the appropriate dosage to prevent such incidents and ensure safe administration.

In the case of a missed dose of Sennosides A and B Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of adverse effects. If you miss multiple doses, contact your healthcare provider for advice on how to safely resume your medication regimen.

To administer Sennosides A and B Syrup/Suspension, shake the bottle well, measure the prescribed dose with a measuring device, and take it orally, following the dosage instructions provided by your healthcare professional, typically once or twice a day, without regard to meals.

Here are the conditions or situations when Sennosides A and B Syrup/Suspension should not be used:

• Should not be used in individuals with a known allergy or hypersensitivity to Sennosides or any of the excipients in the syrup/suspension.
• Contraindicated in patients with acute intestinal inflammation, such as Crohn's disease, ulcerative colitis, or appendicitis.
• Not recommended for individuals with undiagnosed abdominal pain or nausea, as it can mask symptoms.
• Should be avoided in patients with intestinal obstruction, severe dehydration, or electrolyte imbalances.
• Contraindicated in individuals with a history of gastrointestinal perforation or intestinal surgery.
• Not suitable for those with severe hemorrhoidal bleeding or gastrointestinal bleeding.
• Should not be used in individuals with a known or suspected bowel blockage.
• Contraindicated during pregnancy and breastfeeding, unless advised by a healthcare professional.
• Not recommended for children under 6 years of age without medical advice.

The side effects of Sennosides A and B Syrup/Suspension may include:

• Abdominal pain or cramps
• Diarrhea
• Nausea and vomiting
• Electrolyte imbalance (loss of fluids and minerals)
• Weakness or fatigue
• Skin rash or itching
• Increased bowel sounds
• Rectal irritation

Here are the precautions and warnings for Sennosides A and B Syrup/Suspension:

• This medication should not be used in patients with a known allergy or hypersensitivity to Sennosides or any of the inactive ingredients in the syrup.
• It should be used with caution in elderly patients as they may be more susceptible to the effects and side effects of the medication.
• Patients with gastrointestinal conditions such as Crohn's disease, ulcerative colitis, or intestinal obstruction should use this medication with caution and under medical supervision.
• Prolonged use or high doses may lead to electrolyte imbalance, especially loss of potassium. Monitoring of electrolyte levels is recommended.
• Patients with heart conditions should use it with caution as it may cause irregular heart rhythms in some cases.
• Not recommended for long-term use as it may cause dependence and reduced bowel function.
• If symptoms persist or worsen after a few days of use, consult a healthcare professional immediately.
• Pregnant and breastfeeding women should consult their doctor before taking this medication as it may have potential risks.

Following are the drug interactions for Sennosides A and B Syrup/Suspension:

• When taken with cardiac glycosides, it may increase the risk of cardiac arrhythmias due to hypokalemia.
• May reduce the absorption of various medications, including antibiotics and cardiac drugs, when taken simultaneously.
• Can interact with other stimulant laxatives, increasing the risk of dehydration and electrolyte imbalances.
• Antacids containing calcium, magnesium, or aluminum may reduce the effectiveness of Sennosides.
• Potentially increases the risk of kidney damage when used with other nephrotoxic drugs.
• Corticosteroids may enhance the electrolyte imbalance caused by Sennosides.
• Drugs that affect the central nervous system, such as sedatives, may have their effects altered when used concurrently with this medication.

Following are the food interactions for Sennosides A and B Syrup/Suspension:

• Avoid consuming excessive amounts of dairy products, as they can reduce the effectiveness of Sennosides by decreasing their absorption.
• Limit your intake of high-fiber foods like whole grains, legumes, and bran, as they can enhance the laxative effect and potentially lead to diarrhea.
• Fruits like apples, pears, and plums, which are rich in natural sugars, should be consumed in moderation to prevent excessive laxative effects.
• Avoid consuming spicy foods as they can irritate the digestive tract and potentially worsen gastrointestinal symptoms.
• Restrict the consumption of fatty and greasy foods, as they can slow down digestion and reduce the effectiveness of Sennosides.
• Caffeinated beverages like coffee and tea should be limited, as they can stimulate the digestive system and potentially increase the intensity of the laxative effect.
• Stay well-hydrated by drinking plenty of water to support the action of Sennosides and prevent dehydration, especially when using this medication.

Sennosides A and B Syrup/Suspension should be stored in a controlled environment, specifically a cool and dry place at room temperature, ensuring it is shielded from direct sunlight and moisture. To maintain its integrity and prevent contamination, it is crucial to securely seal the medication in its original packaging. Avoid storing it in areas prone to temperature fluctuations, such as bathrooms, kitchens, or near heating devices, as these conditions can compromise the medication's effectiveness. Regularly check the expiration date on the packaging, and when the product is no longer needed or has expired, do not dispose of it through the toilet or drainage systems. Instead, consult a pharmacist or healthcare professional for guidance on appropriate disposal methods. Additionally, keep the medication in a secure location, out of children's reach, to prevent accidental consumption.

Following are the quick tips for Sennosides A and B Syrup/Suspension:

• Consult a healthcare professional for the correct dosage and duration of treatment.
• Shake the bottle vigorously to ensure a uniform mix before each use.
• Administer the syrup with a measuring cup or oral syringe for accurate dosing.
• Consume the syrup immediately after measuring to prevent wastage.
• Store the syrup in a cool, dry place, away from direct sunlight and moisture.
• Do not freeze the syrup as it may affect its consistency.
• Regularly monitor bowel movements and adjust the dosage as directed by your doctor.
• Stay hydrated by drinking plenty of fluids to prevent dehydration.