SENALAX TAB

Sennosides A and B, the active components in Sennosides A and B Tablets, exert their laxative effect primarily through their ability to stimulate the large intestine. These compounds work by entering the colon and being metabolized by the intestinal bacteria into rheinanthrones, which are the active metabolites. These metabolites directly stimulate the intestinal mucosa, particularly the colonic nerve plexuses, leading to increased intestinal motility and secretion. This stimulation enhances peristalsis, the rhythmic contractions that move food through the digestive tract, thereby promoting bowel movements. Additionally, sennosides increase intestinal fluid and electrolyte secretion, which softens the stool, making it easier to pass. The combined effect of increased motility and fluid secretion contributes to the overall laxative action of Sennosides A and B Tablets, making them effective in treating constipation.

Laxative

Tablet

The following are the uses of Sennosides A and B Tablet:

• Used for short-term relief of constipation, helping to promote bowel movements.
• Used for clearing the bowel before surgeries or certain medical procedures.
• Used for treating occasional constipation associated with lifestyle changes or travel.
• Used for encouraging bowel movement after childbirth or in post-operative recovery.
• Used for gently stimulating the intestines to reduce discomfort in chronic constipation.
• Used for supporting regular bowel function in elderly patients or those with limited mobility.
• Used for assisting in the management of constipation-predominant irritable bowel syndrome (IBS-C).

To be used as per doctor's prescription, usually at night

In the case of an overdose of Sennosides A and B Tablets, the primary concern is excessive bowel movements and potential dehydration. Symptoms may include severe diarrhea, abdominal pain, and electrolyte imbalances. Promptly seek medical advice, as treatment may involve rehydration therapy and monitoring of vital signs. It is important to note that individuals experiencing an overdose should not induce vomiting without professional guidance.

In the case of a missed dose of Sennosides A and B Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen. It's important to maintain consistency with this medication for optimal results.

To take Sennosides A and B Tablets, swallow the tablet whole with a glass of water, preferably before bedtime, following the dosage instructions provided by your healthcare professional, typically one tablet daily or as directed, without crushing or chewing the tablet.

Here are the conditions or situations when Sennosides A and B Tablet should not be taken:

• Do not take if you have an intestinal blockage, stomach pain, nausea, or vomiting.
• Contraindicated in individuals with an allergy or hypersensitivity to Sennosides or any of its components.
• Not suitable for individuals with undiagnosed abdominal pain, appendicitis, or inflammatory bowel diseases.
• Avoid using if you have a sudden change in bowel habits that has lasted for more than 2 weeks.
• Should not be used in individuals with severe dehydration or electrolyte imbalances.
• Do not administer to children under 6 years of age without medical advice.
• Contraindicated during pregnancy and breastfeeding, unless advised by a healthcare professional.
• Not recommended for individuals with heart disease or kidney disease.
• Discontinue use and seek medical attention if you experience severe abdominal pain, rectal bleeding, or no bowel movement after using the medication.

The side effects of Sennosides A and B Tablet may include:

• Abdominal cramps
• Diarrhea
• Nausea and vomiting
• Electrolyte imbalance (especially with prolonged use)
• Dehydration
• Skin rash or itching
• Allergic reactions
• Increased urination

Following are the precautions and warnings for Sennosides A and B Tablet:

• Not suitable for individuals with a known allergy or hypersensitivity to Sennosides or any of its ingredients.
• Should be used with caution in elderly patients as they may be more susceptible to the effects and side effects of the medication.
• Patients with gastrointestinal conditions such as Crohn's disease, ulcerative colitis, or intestinal obstruction should use this medication under medical supervision.
• Dehydration is a potential risk, especially in hot weather or with excessive use; ensure adequate fluid intake while taking this medication.
• Prolonged use may lead to electrolyte imbalances, particularly potassium depletion, which can cause muscle weakness and irregular heartbeat.
• If abdominal pain, nausea, or vomiting occur, discontinue use and seek medical advice.
• Not recommended for long-term use without medical supervision, as it may cause laxative dependency and worsen constipation.
• Patients with kidney disease should exercise caution and consult a healthcare professional before use.

Following are the drug interactions for Sennosides A and B Tablet:

• Can interact with cardiac glycosides, increasing the risk of cardiac arrhythmias. Close monitoring is necessary.
• May decrease the absorption of various medications due to its laxative effect, including antibiotics and oral contraceptives.
• Potentially reduces the efficacy of diuretics by altering electrolyte balance.
• When combined with other stimulant laxatives, it may lead to excessive bowel movements and dehydration.
• Antacid medications can decrease the effectiveness of Sennosides, as they may neutralize the acidic environment required for its action.
• Taking Sennosides with other drugs that cause electrolyte imbalances, such as corticosteroids, may increase the risk of hypokalemia.
• It may interact with warfarin, potentially enhancing anticoagulant effects and increasing the risk of bleeding.

Following are the food interactions to consider with Sennosides A and B Tablets:

• Avoid consuming excessive amounts of apple, pear, or peach as these fruits contain tannins that can reduce the effectiveness of Sennosides.
• Dairy products, especially milk, may decrease the absorption of Sennosides, so it's best to separate milk consumption from taking the tablets by at least 2-3 hours.
• High-fiber foods like whole grains, legumes, and leafy greens may enhance the effects of Sennosides, potentially causing stronger bowel movements.
• Avoid grapefruit and grapefruit juice as they can interfere with the breakdown of Sennosides, increasing the risk of side effects.
• Alcohol consumption may intensify the effects of Sennosides on the digestive system, potentially causing dehydration and electrolyte imbalances.
• Consuming adequate water and staying hydrated is crucial when taking Sennosides to prevent dehydration and ensure proper bowel movement.
• Avoid high-fat meals as they may delay the absorption of Sennosides, affecting the medication's effectiveness.

Sennosides A and B Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. It is crucial to keep the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. Avoid storing them in bathrooms or near heat-emitting appliances to prevent exposure to temperature fluctuations. Always check the expiration date before use, and dispose of any unused or expired tablets responsibly. Do not flush them or pour them down the drain; instead, seek guidance from a pharmacist or healthcare professional for appropriate disposal methods. Keep the medication out of children's reach to prevent accidental consumption.

No

Following are the quick tips for Sennosides A and B Tablets:

• Consult a healthcare professional for personalized advice and dosage recommendations.
• Swallow the tablets whole with a full glass of water to aid in swallowing and absorption.
• Take the tablets as directed, typically once or twice daily, at the same time each day.
• Do not crush or chew the tablets, as this may alter their effectiveness.
• If you experience mild stomach discomfort, try taking the tablets with food or after meals.
• Ensure you stay well-hydrated while taking these tablets to prevent dehydration.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Keep the medication out of reach of children and pets to prevent accidental consumption.