Sense-T (Sensitive Teeth) 40g Toothpaste

Strontium ranelate toothpaste primarily works through two distinct mechanisms of action. Firstly, it promotes remineralization of tooth enamel. Strontium ions in the toothpaste have a chemical structure similar to calcium, allowing them to integrate into the hydroxyapatite crystal structure of the enamel. This process helps repair microscopic defects and strengthens the enamel, making it more resistant to acid attacks and decay. Secondly, strontium ranelate inhibits the formation and activity of osteoclasts, cells responsible for bone resorption, while simultaneously stimulating osteoblast activity, which promotes bone formation. By modulating these cellular processes, strontium ranelate enhances bone density and strengthens the alveolar bone supporting the teeth, potentially reducing the risk of tooth mobility and loss.

Strontium-based drug.

Toothpaste

The following are the uses of Strontium Ranelate Toothpaste:

• Used for preventing and treating osteoporosis in postmenopausal women.
• Used to increase bone mineral density, reducing the risk of fractures.
• Used to promote bone formation and improve bone strength.
• Used for managing conditions like periodontal disease and dental implants.
• Used to enhance oral health and support overall bone health.
• Used as a supplement for individuals with calcium or vitamin D deficiencies.
• Used to aid in the healing of bone injuries or fractures.
• Used to maintain healthy bones and reduce age-related bone loss.

In the case of an overdose of Strontium Ranelate Toothpaste, it is important to seek medical advice promptly. Ingesting large amounts of this toothpaste may lead to gastrointestinal symptoms such as nausea, vomiting, and abdominal pain. Additionally, excessive strontium ranelate absorption can potentially affect bone metabolism and calcium levels. Timely intervention and supportive care may be required to manage these effects effectively.

In the case of a missed dose of Strontium Ranelate Toothpaste, it is generally recommended to use the toothpaste as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. Consult your healthcare provider if you frequently miss doses or have concerns about maintaining a consistent treatment routine.

To use Strontium Ranelate Toothpaste, apply a pea-sized amount to a soft-bristled toothbrush, brush your teeth gently for at least 2 minutes, and rinse thoroughly with water, preferably twice a day or as directed by your dentist.

Here are the conditions and situations when Strontium Ranelate Toothpaste should not be used:

• Do not use if you are allergic to strontium ranelate or any other ingredients in the toothpaste formulation.
• Not suitable for individuals with a history of severe allergic reactions (anaphylaxis).
• Contraindicated in patients with a rare condition called hypophosphatasia, which affects bone mineralization.
• Should not be used in individuals with severe kidney disease or those on dialysis.
• Not recommended for children and adolescents under 18 years of age, as its safety and efficacy have not been established in this age group.
• Avoid using Strontium Ranelate Toothpaste if you have a condition called hypercalcemia (high calcium levels in the blood).
• Do not use if you have a history of blood clots or are at high risk of developing blood clots.
• Contraindicated in individuals with active or recent gastrointestinal disorders that may affect the absorption of strontium ranelate.

The side effects of Strontium Ranelate Toothpaste may include:

• Mouth irritation or burning sensation
• Gum irritation or swelling
• Allergic reactions such as rash, itching, or swelling
• Tooth sensitivity
• Dry mouth
• Altered taste sensation
• Staining of teeth with prolonged use
• Mild discomfort or tingling sensation in the mouth
• Rare cases of allergic reactions affecting the skin or breathing difficulties

Following are the precautions and warnings for Strontium Ranelate Toothpaste:

• Avoid swallowing the toothpaste; it is for dental use only and should not be ingested.
• Not suitable for individuals with a known allergy to strontium ranelate or any other ingredients in the toothpaste.
• If you have or have ever had kidney stones, consult your dentist or healthcare provider before use, as strontium can increase the risk of stone formation.
• Discontinue use and seek medical attention if you experience any allergic reactions, such as swelling of the face, lips, or throat, or difficulty breathing.
• Keep out of reach of children. If accidentally swallowed, contact a healthcare professional or poison control center immediately.
• This toothpaste is not intended for use in children unless under the supervision of a dentist or healthcare provider.
• Patients with a history of gastrointestinal disorders should use with caution and consult a dentist or doctor if any adverse effects occur.

Following are the drug interactions for Strontium Ranelate Toothpaste:

• Interaction with other strontium-containing products can lead to an excessive intake of strontium, potentially causing adverse effects.
• May reduce the absorption of tetracycline antibiotics when taken simultaneously, delaying the onset of antibiotic action.
• Strontium ranelate can bind to phosphate in the gastrointestinal tract, affecting the absorption of phosphate-containing medications.
• Antacids containing aluminum or magnesium may decrease the absorption of strontium ranelate if taken simultaneously.
• Thiazide diuretics may increase the risk of hypercalcemia when used with strontium ranelate, as they can increase calcium reabsorption.
• Calcium supplements or calcium-rich foods should be taken at different times to prevent potential interactions affecting strontium absorption.
• Bisphosphonates and strontium ranelate may have similar mechanisms of action, and concurrent use may lead to reduced effectiveness of either drug.

Following are the food interactions for Strontium Ranelate Toothpaste:

• Avoid excessive consumption of calcium-rich foods like dairy products, spinach, and kale, as high calcium levels can reduce strontium absorption.
• Limit the intake of carbonated drinks as they may decrease the effectiveness of strontium ranelate by altering the pH balance in the mouth.
• Acidic foods such as citrus fruits and tomatoes may interfere with the absorption of strontium, so consider using the toothpaste at a different time from consuming these foods.
• Avoid foods high in oxalates like rhubarb, spinach, and sweet potatoes, as oxalates can bind with strontium and reduce its absorption.
• Do not consume alcohol while using strontium ranelate, as it may reduce bone formation and counteract the medication's benefits.
• Maintain a balanced diet rich in essential nutrients, as this medication is often used to support bone health.
• Ensure adequate fluid intake to aid in the absorption and distribution of strontium ranelate throughout the body.
• Consult a healthcare professional or dentist for personalized advice regarding specific dietary considerations and potential food interactions.

Strontium ranelate toothpaste should be stored in a cool and dry location, preferably at room temperature, away from direct sunlight and moisture. Keep the toothpaste in its original packaging, ensuring the cap is tightly sealed to maintain its integrity and prevent contamination. Avoid placing it in high-temperature areas like near stoves or radiators, as heat can alter the toothpaste's properties. Pay attention to the expiration date on the tube, and dispose of any expired or unused toothpaste responsibly. Do not dispose of it by flushing or pouring it down the drain; instead, consult your pharmacist or local waste management guidelines for safe disposal methods. Keep the toothpaste out of children's reach to prevent accidental ingestion.

Following are the quick tips for Strontium Ranelate Toothpaste:

• Brush your teeth twice daily with a pea-sized amount of toothpaste for optimal oral care.
• Gently brush for at least 2 minutes, focusing on all tooth surfaces and along the gum line.
• Use a soft-bristled toothbrush to avoid damaging enamel and gums.
• Avoid swallowing the toothpaste; spit it out after brushing.
• Maintain a consistent oral hygiene routine for best results.
• Visit your dentist regularly for check-ups and professional cleanings.
• Store the toothpaste at room temperature, away from direct sunlight.