SEPIDYL GEL 15G

Chlorhexidine gel's primary mechanism of action is based on its ability to disrupt the cell membrane of microorganisms, leading to cell death. The active ingredient, chlorhexidine, is a potent antimicrobial agent that binds strongly to the negatively charged sites on bacterial cell walls and certain cell membranes. This binding process disrupts the integrity of the microbial cell membrane, causing it to become permeable and leak essential components, ultimately resulting in cell lysis and death. Chlorhexidine is particularly effective against a wide range of bacteria, including Gram-positive and Gram-negative bacteria, as well as some fungi and viruses, making it a versatile antimicrobial agent.

Chlorhexidine

Antiseptic/Disinfectant.

Gel

The following are the uses of Chlorhexidine Gel:

• Used for disinfecting and cleaning minor wounds, scrapes, and cuts to prevent infection.
• Used for maintaining oral hygiene, especially in dental procedures and oral surgeries.
• Used for reducing the risk of infection during surgical procedures when applied to the skin.
• Used for treating and managing skin conditions like acne and dermatitis.
• Used for disinfecting the hands, ensuring proper hygiene in medical settings.
• Used for preventing infections in catheter insertion sites.
• Used for promoting healing and preventing bacterial growth in post-operative care.

In the case of an overdose of Chlorhexidine Gel, it is important to recognize the potential symptoms and take appropriate action. Overuse of this gel can lead to skin irritation, redness, and a burning sensation at the application site. If ingested, it may cause nausea, vomiting, and in severe cases, gastrointestinal issues. Immediate medical advice should be sought if an overdose is suspected, and the affected area should be thoroughly rinsed with water to minimize further irritation.

In the case of a missed dose of Chlorhexidine Gel, it is important to apply the gel as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular application schedule. Do not apply extra gel to make up for the missed dose, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your treatment. It is advisable to set reminders or alarms to help you stay on track with your medication schedule.

To use Chlorhexidine Gel, apply a small amount to your clean hands and gently rub it onto the affected area, ensuring complete coverage, and allow it to dry without rinsing for maximum effectiveness.

Here are the situations when Chlorhexidine Gel should not be used:

• Avoid using Chlorhexidine Gel if you have a known allergy or sensitivity to chlorhexidine or any other ingredients in the gel.
• Do not use it on open wounds or severely damaged skin.
• Contraindicated for patients with a history of anaphylactic or severe hypersensitivity reactions to chlorhexidine.
• Not suitable for use in the eyes or ears; avoid contact with these areas.
• Do not swallow or ingest the gel; it is for external use only.
• Discontinue use if skin irritation, redness, or any adverse reaction occurs.
• Avoid using Chlorhexidine Gel on infants or newborns, especially for diaper rash or on large areas of the skin.
• Do not use it on patients with a history of skin conditions like eczema or severe skin reactions.
• Should not be used on patients who have shown poor tolerance or adverse effects to chlorhexidine in the past.

The side effects of Chlorhexidine Gel may include:

• Skin irritation or redness at the application site
• Itching or burning sensation
• Allergic reactions, such as rash or hives
• Swelling of the face, lips, or tongue
• Difficulty breathing or swallowing
• Peeling or blistering of the skin
• Dryness or flakiness of the treated skin
• Temporary staining of the teeth (when used orally)

Following are the precautions and warnings:

• Chlorhexidine Gel should not be used if you are allergic to chlorhexidine or any other ingredients in the gel.
• Avoid contact with eyes, ears, and other sensitive mucous membranes. If accidental contact occurs, rinse thoroughly with water.
• Do not swallow the gel. It is for external use only.
• Caution is advised for patients with pre-existing skin conditions. It may cause skin irritation or allergic reactions in some individuals.
• Do not use on open wounds, severe burns, or large areas of broken skin without medical advice.
• Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.
• If you are using other topical medications, consult a healthcare professional before applying Chlorhexidine Gel to ensure there are no interactions.

Following are the drug interactions for Chlorhexidine Gel:

• Chlorhexidine may interact with other topical medications containing silver, as it can reduce the effectiveness of both agents.
• Avoid using other antiseptic or antibiotic products concurrently without medical advice, as it may lead to skin irritation or reduced effectiveness.
• Alcohol-based products can affect the activity of Chlorhexidine, potentially decreasing its effectiveness.
• Chlorhexidine can bind to anionic drugs and substances, such as anionic silver, anionic detergents, and anionic polymers, leading to reduced activity.
• Avoid using quaternary ammonium compounds or salts with Chlorhexidine, as they can form inactive complexes.
• Iodine solutions or tinctures may reduce the effectiveness of Chlorhexidine, and concurrent use should be avoided.
• The use of Chlorhexidine with hydrogen peroxide may decrease its effectiveness due to the formation of gas bubbles.

Following are the food interactions for Chlorhexidine Gel:

• Avoid consuming alcohol-based mouthwashes or beverages immediately after using Chlorhexidine Gel as it may cause a temporary numbing or burning sensation in the mouth.
• Avoid hot or spicy foods after applying the gel, as it can irritate the treated area and cause discomfort.
• Dairy products like milk, cheese, and yogurt should be consumed with caution as they can reduce the effectiveness of Chlorhexidine by binding to the medication.
• Avoid eating acidic foods like citrus fruits, tomatoes, and vinegar-based dressings, as they can alter the pH balance in the mouth and potentially reduce the antimicrobial activity of Chlorhexidine.
• Tannin-rich foods such as tea, coffee, and red wine may stain your teeth if consumed shortly after applying Chlorhexidine Gel.
• Sugary foods and drinks should be limited as they can counteract the benefits of Chlorhexidine and promote bacterial growth.
• Avoid food and drinks with strong coloring agents to prevent temporary discoloration of the treated area.

Chlorhexidine Gel should be stored in a cool, well-ventilated area, preferably in a dedicated storage cabinet or room, ensuring it is kept away from direct sunlight, heat, and moisture. It is crucial to store the gel in its original container, tightly sealed, to maintain its integrity and prevent contamination. Do not freeze the gel as it may alter its consistency. When disposing of Chlorhexidine Gel, do not pour it down the drain or flush it into the sewage system. Instead, follow local regulations for hazardous waste disposal or consult healthcare professionals for guidance on proper disposal methods to ensure environmental safety. Keep the gel out of children's reach to prevent accidental contact or ingestion.

Following are the quick tips for Chlorhexidine Gel:

• Ensure hands are clean before applying the gel to the affected area.
• Apply a thin layer of gel to the skin as directed by your healthcare professional.
• Gently massage the gel into the skin until it is completely absorbed.
• Use the gel regularly to maintain its effectiveness.
• Avoid contact with eyes; rinse thoroughly with water if contact occurs.
• Do not swallow the gel; it is for external use only.
• Store the gel at room temperature, away from direct sunlight and moisture.