Sermol Tab 200s tab

Paracetamol, also known as acetaminophen, primarily exerts its analgesic and antipyretic effects by inhibiting the synthesis of prostaglandins in the central nervous system. It acts on specific pain-related regions of the brain and spinal cord, reducing the perception of pain. Aceclofenac, on the other hand, is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting the enzyme cyclooxygenase (COX), which is responsible for the production of prostaglandins. By blocking COX enzymes, aceclofenac reduces the formation of prostaglandins, resulting in decreased inflammation, pain, and fever. This combination of paracetamol and aceclophenac provides a synergistic effect, as they target different pathways involved in pain and inflammation, leading to enhanced pain relief and anti-inflammatory action.

Analgesic, Non-steroidal anti-inflammatory drug (NSAID).

Tablet

The following are the uses of Paracetamol, Aceclofenac Tablet:

• Used for relieving pain and reducing fever
• Used for managing mild to moderate pain and inflammation
• Used for headaches, toothaches, and post-vaccination fever
• Used for providing temporary relief from joint and muscle pain
• Used for reducing discomfort associated with menstrual cramps
• Used for treating pain and inflammation in conditions like arthritis
• Used for alleviating pain and inflammation after minor injuries or surgeries
• Used for managing symptoms of cold and flu, including body aches and fever

The following dosage can be followed:

• Take 2 tablets every 6 hours for high grade fever
• 1 tablet for mild to moderate pain every 8 hours

In the case of an overdose of Paracetamol and Aceclofenac Tablet, prompt medical attention is required. The symptoms of an overdose may include nausea, vomiting, abdominal pain, and potential liver damage. Quick action is necessary to prevent severe complications. Treatment involves gastric decontamination, supportive care, and managing any resulting liver toxicity. It is crucial to seek professional medical advice for the appropriate course of action.

In the case of a missed dose of Paracetamol, Aceclofenac Tablet, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication. It's important to maintain a consistent dosing schedule for the best therapeutic effect.

To take the Paracetamol, Aceclofenac Tablet, swallow the tablet with a glass of water, preferably with or after a meal, following the dosage instructions provided by your healthcare professional, ensuring you do not exceed the recommended daily intake.

Here are the situations when Paracetamol, Aceclofenac Tablet should not be used:

• Avoid using if you have a known allergy to Paracetamol or Aceclofenac or any other similar medications.
• Do not take this medicine if you have severe liver or kidney disease.
• Not suitable for individuals with a history of gastrointestinal bleeding or perforation.
• Contraindicated in patients with heart disease or a history of stroke.
• Should not be used if you are currently taking anticoagulant medications.
• Avoid using this medicine if you have a history of asthma or allergic reactions triggered by painkillers.
• Not recommended for individuals with a history of stomach ulcers or bleeding disorders.
• Do not take this medicine if you have recently undergone heart bypass surgery.
• Contraindicated during the last trimester of pregnancy.

The side effects of Paracetamol, Aceclofenac Tablet may include:

• Stomach pain or discomfort
• Nausea and vomiting
• Diarrhea
• Constipation
• Headache
• Dizziness or vertigo
• Skin rashes or itching
• Increased liver enzymes (liver-related issues)

Following are the precautions and warnings for Paracetamol, Aceclofenac Tablet:

• This medication should be used with caution in patients with a history of gastrointestinal problems, as it may cause stomach bleeding or ulcers.
• Patients with liver or kidney disease should be closely monitored while taking this medicine, and dosage adjustments may be necessary.
• Avoid excessive alcohol consumption while using this medication as it can increase the risk of liver damage.
• Do not take more than the recommended dose, as an overdose can lead to severe liver or kidney problems.
• If you have a history of allergic reactions to NSAIDs (Non-Steroidal Anti-Inflammatory Drugs), use with caution and inform your doctor.
• Patients with asthma or other respiratory conditions should be aware that this medication may cause bronchospasm.
• Discontinue use and seek medical attention if you experience skin rashes, itching, or any signs of an allergic reaction.
• Consult your doctor before taking this medication if you are pregnant, planning to become pregnant, or breastfeeding.

Following are the drug interactions for Paracetamol, Aceclofenac Tablet:

• Paracetamol may increase the risk of bleeding when taken with anticoagulants like warfarin or antiplatelet drugs.
• Aceclofenac can reduce the efficacy of diuretics and antihypertensive medications.
• Concomitant use with other non-steroidal anti-inflammatory drugs (NSAIDs) may increase the risk of gastrointestinal bleeding and renal toxicity.
• It may decrease the hypotensive effects of beta-blockers and ACE inhibitors.
• Aceclofenac can increase plasma concentrations of lithium and methotrexate, requiring dose adjustments.
• Paracetamol can affect the metabolism of certain anticonvulsant drugs, increasing their levels.
• Caution is advised when using with corticosteroids, as it may increase the risk of gastrointestinal ulceration.

Following are the food interactions for Paracetamol, Aceclofenac Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can interfere with the metabolism of Aceclofenac, leading to increased levels in the blood and potential side effects.
• Alcohol intake is not recommended as it can increase the risk of gastrointestinal bleeding and liver damage when combined with Aceclofenac.
• Avoid fatty or oily meals as they may delay the absorption of Aceclofenac, affecting its effectiveness.
• Caffeine-rich foods and beverages should be limited as they can potentially increase the metabolism of Paracetamol, reducing its duration of action.
• Consuming foods high in Vitamin C may enhance the absorption of Paracetamol, which could be beneficial for pain relief.
• Avoid excessive salt intake as it can increase water retention and potentially interact with the diuretic effects of Aceclofenac.
• Spicy foods may irritate the stomach and exacerbate gastrointestinal side effects when taking Aceclofenac.
• Always ensure adequate hydration when taking Paracetamol and Aceclofenac to prevent potential kidney-related issues.

Paracetamol, Aceclofenac Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The original packaging should be retained, keeping the tablets secure and preventing contamination. Avoid exposure to heat or cold, and never store them in the bathroom or near a kitchen stove. It's crucial to regularly check the expiration date, and if the tablets are past their prime or no longer needed, they should be disposed of properly. Do not flush or pour them down the drain; consult a pharmacist or local waste disposal company for safe disposal guidelines. Always keep medications out of children's reach to prevent accidental consumption.

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Following are the quick tips for Paracetamol, Aceclofenac Tablet:

• Consult your doctor for dosage instructions based on your condition and medical history.
• Take the tablet with a full glass of water, preferably with or after food.
• Swallow the tablet whole, do not crush or chew.
• Avoid alcohol consumption while taking this medication.
• Inform your doctor about all medications you are currently taking to prevent potential interactions.
• If you experience stomach pain or discomfort, try taking the tablet with food.
• Store the medication in a cool, dry place, away from direct sunlight and moisture.
• Do not share your medication with others, even if they have similar symptoms.