Valsartan is an orally active, specific and selective angiotensin receptor blocker drug. As an Angiotensin II receptor blocker; this drug selectively and specifically antagonizes the action of angiotensin II; which is a potent vasoconstrictor that influences the mechanism of blood pressure (BP) regulation. This drug works by blocking the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, adrenal gland and vascular smooth muscles. Mechanism of action of this drug results in relaxation of blood vessels that leads to normal regulation of blood flow in vessels.
Ingredients
Valsartan
Dosage Form
Tablet
Uses
Used for the treatment of Hypertension, heart failure with reduced ejection fraction and post–myocardial infarction.
Dosage
Dose must be taken according to doctor’s advice only; doses given below are suggested as supportive literature for better understanding in some areas of requirements. For hypertension, Adolescents ≥17 years, oral initial dose is 80 mg or 160 mg once daily. In Heart failure with reduced ejection fraction and in ST-elevation myocardial infarction initial dose is 20 mg twice daily; may increase dose as tolerated up to 160 mg twice daily under close monitoring to avoid hypotension.
In case of Overdose
Consult your doctor immediately in case of overdose as it may cause hypotension.
Missed Dose
In case you missed any dose, take the next dose as soon as you remember, but don't double your next dose to compensate for the missed one.
How To Use
Take it orally with your doctor’s instructions.
When Not to Use
The use of angiotensin II receptor blockers should generally be avoided in women planning a pregnancy. Use of this medicine during pregnancy can cause serious damage to the fetus.