Silimarin (200mg) 20 Tablets

Silymarin, the active component in Silymarin Tablets, exerts its effects primarily through its interaction with the liver. The mechanism of action involves multiple pathways. Firstly, silymarin has potent antioxidant properties, allowing it to neutralize free radicals and reduce oxidative stress in liver cells. This helps protect the liver from damage caused by toxins and various harmful substances. Secondly, it inhibits the production of certain inflammatory molecules, reducing liver inflammation. Silymarin also stabilizes cell membranes, preventing the entry of toxic substances into liver cells. Additionally, it enhances protein synthesis, promoting liver cell regeneration and repair. By modulating various intracellular signaling pathways, silymarin supports liver function and aids in the management of liver-related conditions. Its ability to protect and support liver health makes it a valuable component in the treatment and management of liver disorders.

Phytomedicine, hepatoprotectant.

Tablet

The following are the uses of Silymarin Tablet:

• Used for liver protection and to treat liver diseases such as cirrhosis, hepatitis, and fatty liver.
• Used for reducing liver damage caused by medications and toxins.
• Used for supporting liver function in those with alcohol-related liver issues.
• Used as an antioxidant to reduce inflammation and oxidative stress in the liver.
• Used for promoting liver regeneration and recovery after injury or surgery.
• Used for improving liver enzyme levels and overall liver health.
• Used for enhancing the effectiveness of other liver medications.
• Used for long-term liver health maintenance.

In the case of an overdose of Silymarin Tablets, it is important to remain calm and take appropriate action. The specific steps to take may vary depending on the severity of the overdose. If a large quantity of tablets has been ingested, contact a healthcare professional or a poison control center immediately for guidance. They will provide instructions on what to do next, which may include inducing vomiting or administering activated charcoal to help absorb the excess medication.

In the case of a missed dose of Silymarin Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, consult your healthcare provider for guidance on how to adjust your dosing schedule and ensure you're receiving the appropriate treatment. It is advisable to set reminders or keep a medication schedule to minimize the chances of missing doses in the future.

To take Silymarin Tablets, swallow the tablet whole with a glass of water, preferably during a meal or as directed by your healthcare professional, following the prescribed dosage and schedule provided by your doctor or pharmacist.

Following are the conditions/situations when Silymarin Tablet is contraindicated or should not be used:

• Do not take if you have a known allergy to Silymarin or any of its active ingredients.
• Avoid using this medication if you have a history of chronic liver disease or liver failure.
• Not suitable for individuals with blocked bile ducts or bile duct obstruction.
• Should not be used if you have a history of autoimmune hepatitis.
• Contraindicated for patients with Wilson's disease.
• Avoid Silymarin if you have a history of severe kidney problems or are on dialysis.
• Do not use if you are pregnant or breastfeeding, unless advised by your doctor.

The side effects of Silymarin Tablet may include:

• Nausea and vomiting.
• Itchy skin or rashes.
• Stomach pain and discomfort.
• Diarrhea or loose stools.
• Loss of appetite.
• Constipation.
• Dizziness or feeling lightheaded.
• Fatigue and weakness.

Following are the precautions and warnings for Silymarin Tablet:

• Individuals with a known allergy to Silymarin or related compounds should not take this medication.
• Patients with liver disease or liver-related conditions should use this medication with caution and under medical supervision, as it may affect liver function.
• Silymarin Tablet may interact with other medications, including anti-anxiety drugs, certain antibiotics, and cholesterol-lowering drugs, so it is important to inform your healthcare provider of all medications you are taking.
• Not recommended for use during pregnancy or breastfeeding unless advised by a healthcare professional.
• Patients with diabetes should monitor their blood sugar levels regularly, as Silymarin may lower blood sugar.
• If you are scheduled for surgery, inform your doctor about Silymarin use, as it may affect blood sugar control during surgery.
• Keep Silymarin Tablets out of reach of children and pets, and store them in a cool, dry place as directed on the packaging.

Following are the drug interactions for Silymarin Tablet:

• It may reduce the effectiveness of oral contraceptives, potentially leading to breakthrough bleeding.
• Silymarin can increase the effects of diabetes medications, leading to low blood sugar levels.
• Antifungal medications like itraconazole and ketoconazole may have increased blood levels when taken with Silymarin.
• Interactions with cholesterol-lowering medications are possible, affecting their absorption.
• May reduce the absorption of certain antibiotics, such as ciprofloxacin and levofloxacin.
• Silymarin can enhance the effectiveness of immunosuppressant drugs, potentially requiring dose adjustments.
• Some medications for high blood pressure may have decreased efficacy when combined with Silymarin.

Following are the food interactions for Silymarin Tablet:

• Grapefruit juice should be consumed with caution as it may alter the metabolism of Silymarin, affecting its absorption and potentially increasing its levels in the body.
• High-fat meals can delay the absorption of Silymarin, potentially reducing its effectiveness, so it is advisable to take the tablet on an empty stomach.
• Alcohol consumption should be avoided as Silymarin is believed to protect the liver from alcohol-induced damage, and concurrent use may impact the liver's health.
• Garlic supplements might reduce Silymarin's effectiveness due to their potential to enhance its metabolism, leading to lower blood levels.
• Green tea may decrease the absorption of Silymarin, so it is recommended to separate the consumption of green tea and Silymarin by a few hours.
• Certain vegetables like broccoli, Brussels sprouts, and cabbage contain compounds that might influence Silymarin's metabolism, potentially affecting its efficacy.
• Foods rich in antioxidants, such as berries and dark chocolate, could theoretically interact with Silymarin's antioxidant properties, although this is generally considered beneficial.
• Milk thistle, a natural source of Silymarin, should not be consumed in excess in combination with Silymarin tablets to prevent potential additive effects.

Silymarin Tablets should be stored in a cool, dry place, preferably at room temperature between 68°F and 77°F (20°C and 25°C). Protect the tablets from excessive heat, moisture, and direct sunlight, as these conditions can degrade the medication. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to environmental factors. Do not use the tablets if there are signs of tampering or if the packaging appears damaged. When disposing of unused or expired Silymarin Tablets, do not throw them into the trash or flush them down the toilet. Instead, follow local guidelines for medication disposal or consult a pharmacist for advice on safe disposal methods to protect the environment and prevent misuse.

Following are the quick tips for Silymarin Tablet:

• Take the tablet as directed by your doctor, typically one to three times a day.
• Consume the tablet with a full glass of water for better absorption.
• It is best to take Silymarin on an empty stomach, at least 30 minutes before meals.
• Avoid crushing or chewing the tablet; swallow it whole for maximum effectiveness.
• If you experience mild stomach discomfort, taking the tablet with food can help.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Do not share this medication with others, even if they have similar symptoms.