SILINOR SYP 200ML

The active ingredient in Milk Thistle, silymarin, is a complex mixture of flavonoids, including silybin, silydianin, and silychristin. These compounds exert their effects primarily by interacting with the liver cells. The mechanism of action involves several processes. Silymarin has potent antioxidant properties, neutralizing free radicals and reducing oxidative stress in the liver. It inhibits the production of inflammatory mediators, reducing liver inflammation. Additionally, silymarin stabilizes the cell membrane of liver cells, preventing the entry of toxic substances and promoting liver regeneration by stimulating protein synthesis and enhancing DNA repair. It also inhibits the binding of toxins to liver cell receptors, further protecting the liver from damage. This multifaceted mechanism of action contributes to Milk Thistle's reputation as a liver-protective and supportive agent.

Herbal supplement

Suspension

The following are the uses of Powdered Milk Thistle Syrup/Suspension:

• Used for supporting liver health and promoting detoxification
• Used for treating liver damage and cirrhosis
• Used as a supplement to improve liver function in those with liver diseases
• Used to reduce liver inflammation and protect liver cells
• Used to aid in the treatment of hepatitis and alcoholic liver disease
• Used to enhance liver regeneration and recovery
• Used to support overall liver function and digestion
• Used as a natural remedy to relieve symptoms of liver-related issues

In the case of an overdose of Powdered Milk Thistle Syrup/Suspension, it is important to recognize the potential symptoms and act promptly. Nausea, vomiting, and diarrhea may occur, along with more severe effects like liver toxicity. If an overdose is suspected, seek medical advice immediately. Treatment may involve managing symptoms and providing supportive care, ensuring the patient's well-being and preventing any long-term complications.

In the case of a missed dose of Powdered Milk Thistle Syrup/Suspension, it is recommended to take the missed dose as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It is important to maintain consistency in administering this medication for optimal therapeutic benefits. Consult your healthcare provider if you have any concerns or questions regarding missed doses.

To take Powdered Milk Thistle Syrup/Suspension, mix the prescribed amount of powder with water as directed, stir well until dissolved, and administer the measured dose using an oral syringe or spoon, ensuring accuracy and consistency by following the instructions provided by your healthcare professional.

Following are the conditions when Powdered Milk Thistle Syrup/Suspension should not be used:

• Do not use if you have a known allergy or hypersensitivity to milk thistle, its extracts, or any other ingredients in the syrup/suspension.
• Avoid if you have severe liver disease or liver failure.
• Not suitable for individuals with a history of bile duct obstruction or gallstones.
• Should not be administered to infants or very young children without medical advice.
• Contraindicated in individuals with a history of anaphylactic reactions to plants in the Asteraceae/Compositae family (e.g., daisies, ragweed).
• Avoid if you are breastfeeding, as there is insufficient information on the safety of milk thistle in nursing mothers.
• Do not use if you are taking medications that are metabolized by the liver, without consulting a healthcare professional, as milk thistle may affect their metabolism.

The side effects of Powdered Milk Thistle Syrup/Suspension may include:

• Gastrointestinal issues such as diarrhea, nausea, and stomach discomfort.
• Allergic reactions, including skin rashes, itching, and hives.
• Headaches and dizziness.
• Fatigue and weakness.
• Altered taste sensation.
• Mild skin discoloration (yellowing).
• In rare cases, it may cause liver enzyme elevation.
• In some individuals, it might trigger a mild laxative effect.

Following are the precautions and warnings for Powdered Milk Thistle Syrup/Suspension:

• Allergic reactions may occur; discontinue use if you experience symptoms like rash, itching, swelling, or difficulty breathing.
• Not recommended for individuals with liver or bile duct disorders; consult a healthcare professional before use.
• May cause gastrointestinal discomfort such as nausea, vomiting, or diarrhea in some individuals.
• Avoid excessive consumption as it may lead to stomach upset or other adverse effects.
• Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.
• Not intended for long-term use; consult a healthcare provider for prolonged use.
• If you are taking other medications, especially those affecting the liver, consult a healthcare professional to ensure safe use.

Following are the drug interactions for Powdered Milk Thistle Syrup/Suspension:

• It may interact with medications metabolized by the liver enzyme CYP3A4, including certain statins, oral contraceptives, and antifungal drugs, potentially altering their effectiveness.
• Milk thistle can affect the absorption of drugs like S-warfarin, potentially reducing its anticoagulant effect, requiring close monitoring.
• Interactions with diabetes medications are possible, as milk thistle may lower blood sugar levels, increasing the risk of hypoglycemia.
• When combined with certain antihypertensive medications, it might lower blood pressure further, potentially causing hypotension.
• Caution is advised with immunosuppressants, as milk thistle may alter their metabolism, affecting treatment outcomes.
• The syrup's potential effect on the liver may influence the metabolism of various medications, including certain antidepressants and antibiotics.
• It may also interact with drugs affecting the gastrointestinal system, such as antacids or laxatives, potentially altering their absorption and effectiveness.

Following are the food interactions for Powdered Milk Thistle Syrup/Suspension:

• Consumption of grapefruit or grapefruit juice should be avoided as it may interfere with the metabolism of Milk Thistle, potentially leading to increased levels of the active compound silymarin in the body.
• Alcohol should be limited or avoided as it can put additional stress on the liver, reducing the effectiveness of Milk Thistle in supporting liver health.
• High-fat meals might affect the absorption of Milk Thistle's active components. It is advisable to take the syrup on an empty stomach or with a light meal.
• Avoid excessive consumption of cruciferous vegetables like broccoli and Brussels sprouts, as they contain compounds that might interact with Milk Thistle's detoxification pathways.
• Limit the intake of foods rich in calcium as they can potentially reduce the absorption of Milk Thistle's beneficial compounds.
• Spicy foods might irritate the digestive system and could potentially reduce the comfort of consuming Milk Thistle syrup.
• It is generally recommended to maintain a balanced diet and stay well-hydrated while taking this supplement to ensure optimal health and support the body's natural processes.

Store Powdered Milk Thistle Syrup/Suspension in a cool, dry area at room temperature, ensuring protection from direct sunlight and moisture. Keep the medication tightly sealed in its original container to maintain its integrity. Avoid bathroom storage or proximity to heat sources like stoves or radiators, as temperature fluctuations can impact the syrup's quality. Dispose of any unused or expired medication responsibly; refrain from flushing or pouring down drains. Consult your pharmacist or healthcare provider for appropriate disposal methods, and keep the medication inaccessible to children to prevent accidental consumption.

Following are the quick tips for Powdered Milk Thistle Syrup/Suspension:

• Consult a healthcare professional for dosage instructions based on your specific needs.
• Ensure the powder is properly mixed with the recommended liquid before consumption.
• Drink plenty of water to aid in digestion and absorption.
• Consume the suspension immediately after preparation for best results.
• Store the powder in a cool, dry place, away from direct sunlight.
• Avoid taking the syrup/suspension if you have a known allergy to milk thistle.
• Monitor your liver health regularly when using this supplement.