Silliver (100mg/5ml) 120ml Suspension

Silymarin, the active component in Silymarin Syrup/Suspension, primarily acts through its antioxidant and hepatoprotective properties. The mechanism of action involves multiple pathways. Silymarin contains flavonoids, including silybin, which have a strong affinity for liver cell membranes. It stabilizes these membranes, preventing the entry of toxins and inhibiting lipid peroxidation. This action helps protect liver cells from damage caused by various toxic substances. Silymarin also stimulates protein synthesis, enhancing liver regeneration and repair. Additionally, it exhibits anti-inflammatory effects by reducing the production of inflammatory mediators, thereby alleviating liver inflammation. By modulating various cellular processes and providing antioxidant support, Silymarin Syrup/Suspension supports liver function and aids in the management of liver-related conditions.

Hepatoprotective (liver-protecting) agent.

Suspension

The following are the uses of Silymarin Syrup/Suspension:

• Used for liver protection and detoxification
• Used for treating liver diseases like cirrhosis and hepatitis
• Used as an antioxidant and anti-inflammatory agent
• Used to improve liver function in patients with liver damage
• Used for supporting liver health in alcohol-related liver disease
• Used for promoting liver regeneration after injury or surgery
• Used as a complementary therapy for liver cancer patients
• Used to enhance the effectiveness of conventional liver treatments

To be used as per doctor's advice

In the case of an overdose of Silymarin Syrup/Suspension, individuals may experience gastrointestinal symptoms such as nausea, vomiting, and diarrhea. The severity of these symptoms can vary depending on the amount ingested. It is important to seek medical advice promptly if an overdose is suspected. Timely intervention and supportive care are crucial to managing any adverse effects and ensuring the well-being of the individual. Prompt medical consultation is recommended to determine the appropriate course of action.

In the case of a missed dose of Silymarin Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare professional for advice on how to safely resume your medication regimen.

To take Silymarin Syrup/Suspension, shake the bottle well, then measure the prescribed dose using a measuring cup or oral syringe, and administer it orally once or twice a day, as directed by your healthcare professional, with or without food.

Following are the conditions/situations when Silymarin Syrup/Suspension should not be used:

• Avoid use in individuals with a known allergy to silymarin, milk thistle, or related plants from the Asteraceae/Compositae family.
• Not suitable for patients with a history of severe liver disease or liver failure.
• Contraindicated in individuals with a blockage in the bile ducts.
• Should not be used in patients with a history of gallstones or gallbladder disease.
• Not recommended for children under 12 years of age due to insufficient data.
• Avoid use if you have a known sensitivity to any of the syrup/suspension's components or excipients.

The side effects of Silymarin Syrup/Suspension may include:

• Nausea and vomiting
• Stomach pain or discomfort
• Diarrhea
• Constipation
• Loss of appetite
• Itching or skin rash
• Darkened urine
• Fatigue or weakness

Following are the precautions and warnings for Silymarin Syrup/Suspension:

• Do not take Silymarin if you are allergic to any of its ingredients, including milk proteins and soya lecithin.
• This syrup should be used with caution in patients with bleeding disorders or those taking anticoagulant medications, as it may affect blood clotting.
• Patients with diabetes should monitor their blood sugar levels regularly, as Silymarin might lower blood sugar.
• Not recommended for children under 12 years of age due to insufficient data on safety and efficacy.
• Silymarin may cause mild gastrointestinal disturbances like nausea, vomiting, or diarrhea in some individuals. Discontinue use if these symptoms persist.
• Patients with a history of liver disease or those currently taking liver-affecting medications should use it under medical supervision.
• Consult a healthcare professional if you are pregnant, breastfeeding, or planning to become pregnant before taking Silymarin.

Following are the drug interactions for Silymarin Syrup/Suspension:

• Silymarin may reduce the effectiveness of medications like cyclosporine and tacrolimus, which are used to suppress the immune system. Close monitoring is necessary.
• It can interact with cholesterol-lowering medications, such as atorvastatin, potentially increasing the risk of liver-related side effects. Regular liver function tests are advised.
• Antihistamines like cetirizine may have their effects decreased when taken with Silymarin.
• The syrup may affect the absorption of certain antibiotics like ciprofloxacin and levofloxacin.
• Silymarin can increase the blood levels of medications metabolized by the liver, including some antidepressants and antipsychotics, potentially leading to increased side effects.
• When combined with antidiabetic medications, Silymarin might lower blood sugar levels, requiring close monitoring.
• Use with caution in patients taking antihypertensive medications, as Silymarin may lower blood pressure.

Following are the food interactions for Silymarin Syrup/Suspension:

• Avoid excessive consumption of alcohol as it can potentially increase the liver-protective effects of Silymarin, but excessive alcohol intake may also counteract the benefits and strain the liver.
• Grapefruit and its juice may affect the metabolism of Silymarin, possibly leading to increased levels in the body, so it's best to avoid it.
• High-fiber foods like whole grains, legumes, and leafy greens can enhance Silymarin's benefits by promoting healthy digestion and supporting liver function.
• Fatty foods can influence the absorption of Silymarin, so it is recommended to consume it with a meal containing a moderate amount of healthy fats.
• Garlic and turmeric, known for their liver-supporting properties, may complement Silymarin's effects and provide additional benefits.
• Green tea, rich in antioxidants, can potentially enhance Silymarin's protective effects on the liver when consumed in moderation.
• While not a food, it's crucial to maintain a balanced diet, as Silymarin works best in conjunction with a healthy lifestyle, ensuring optimal liver function and overall well-being.

Silymarin Syrup/Suspension should be stored in a cool and dry environment, preferably at room temperature, ensuring protection from sunlight and moisture. Maintain the integrity of the medication by keeping it tightly sealed within its original packaging. Avoid storage in bathrooms or proximity to heat-emitting appliances, as temperature fluctuations can impact its effectiveness. Dispose of any unused or expired syrup responsibly; refrain from flushing it down the toilet or pouring it into drains. Consult your pharmacist or healthcare professional for appropriate disposal methods, and keep the medication securely stored away from children to prevent accidental consumption.

No

Following are the quick tips for Silymarin Syrup/Suspension:

• Follow the dosage instructions provided by your healthcare professional for best results.
• Before each use, shake the bottle vigorously to ensure proper mixing.
• Administer the syrup with a glass of water for better absorption; avoid tea, coffee, or dairy products.
• Maintain a consistent routine by taking the medication at the same time daily.
• To minimize gastrointestinal issues, consider taking the syrup with food or after meals.
• Store the medication in a secure location, out of the reach of children.
• Always consult your doctor or pharmacist if you have any questions or concerns about your medication.