Sionex-BD (500mg) 12 Tablets

Cephradine 500mg Tablet, a first-generation cephalosporin antibiotic, exerts its bactericidal effect by disrupting the synthesis of the bacterial cell wall. It specifically targets the final stage of peptidoglycan synthesis, which is essential for maintaining the structural integrity of bacterial cells. Cephradine binds to and inhibits the activity of penicillin-binding proteins (PBPs), which are enzymes responsible for cross-linking the peptidoglycan chains. This interference weakens the cell wall, leading to cell lysis and ultimately causing the death of susceptible bacteria. This mechanism of action is effective against a range of Gram-positive and some Gram-negative bacteria, making Cephradine a valuable agent in the treatment of various bacterial infections.

Cephradine 500mg

Cephradine is a cephalosporin antibiotic.

Tablet

The following are the uses of Cephradine 500mg Tablet:

• Used for treating bacterial infections such as respiratory tract infections, skin and soft tissue infections, and urinary tract infections.
• Used for its effectiveness against a range of bacteria, including Streptococcus and Staphylococcus species.
• Used for combating infections that are resistant to other antibiotics.
• Used for managing acute otitis media (middle ear infection) in children.
• Used for surgical prophylaxis to prevent infections during and after surgery.
• Used for controlling the spread of infection in community settings or healthcare facilities.
• Used for mild to moderate infections, providing a reliable treatment option.

In the case of an overdose of Cephradine 500mg Tablets, individuals may experience symptoms such as nausea, vomiting, diarrhea, and abdominal pain. It is important to seek medical advice promptly. Treatment for overdose may involve managing these symptoms and ensuring the patient's vital signs are stable. In severe cases, medical professionals might consider additional measures to support the individual's health and well-being. Timely intervention can help mitigate potential health risks associated with excessive medication intake.

In the case of a missed dose of Cephradine 500mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for advice on how to safely resume your medication without affecting its efficacy. It is recommended to set reminders or alarms to help you remember to take your medication on time to avoid missed doses.

To take Cephradine 500mg Tablet, swallow the tablet whole with a full glass of water, ensuring you complete the full course as prescribed by your healthcare provider, typically taken every 12 hours or as directed by your doctor.

Following are the conditions or circumstances when Cephradine 500mg Tablet should not be used:

• Avoid use if you have a known allergy to Cephradine or any other cephalosporin antibiotics.
• Do not take if you have a history of severe allergic reactions to penicillin.
• Contraindicated in individuals with a history of gastrointestinal diseases, especially colitis.
• Not recommended for patients with kidney disease or reduced kidney function.
• Should not be used if you have a history of seizures or epilepsy.
• Avoid if you have a history of severe liver disease or impaired liver function.
• Not suitable for individuals with a history of blood disorders or abnormal blood clotting.
• Do not administer to infants, especially premature babies, due to potential risk of displacement of bacteria in the gut.

The side effects of Cephradine 500mg Tablet may include:

• Diarrhea
• Nausea and vomiting
• Skin rashes or itching
• Allergic reactions (hives, swelling, difficulty breathing)
• Headache
• Dizziness
• Abdominal pain
• Vaginal itching or discharge

Following are the precautions and warnings for Cephradine 500mg Tablet:

• Avoid if allergic to Cephradine or any other penicillin antibiotics. Cross-reactivity is possible.
• Kidney function should be monitored during long-term therapy, especially in patients with pre-existing kidney issues.
• Use with caution in individuals with a history of gastrointestinal diseases, particularly colitis, as it may exacerbate these conditions.
• Alcohol consumption is not recommended during treatment, as it may reduce the effectiveness of the medication.
• May cause false positive results in certain medical tests, such as urine glucose tests. Inform your doctor if you are undergoing any tests.
• If you have a history of seizures or other neurological disorders, use with caution as it may increase the risk of seizures.
• Pregnant and breastfeeding women should consult their doctor before use, as it may have potential risks to the fetus and infant.

Following are the drug interactions for Cephradine 500mg Tablet:

• Probenecid can decrease the renal excretion of Cephradine, leading to increased serum levels.
• Concomitant use with other nephrotoxic drugs (e.g., aminoglycosides, amphotericin B) may increase the risk of kidney damage.
• Cephradine may reduce the effectiveness of oral contraceptives, potentially reducing their contraceptive protection.
• Antacids containing aluminum or magnesium can decrease the absorption of Cephradine when taken simultaneously.
• The effectiveness of Cephradine may be reduced when taken with chloramphenicol, a broad-spectrum antibiotic.
• Cephalosporins, including Cephradine, may alter the intestinal flora, potentially decreasing the efficacy of oral typhoid vaccine.
• Caution is advised when using Cephradine with other medications that affect the gastrointestinal tract, as it may increase the risk of gastrointestinal side effects.

Following are the food interactions for Cephradine 500mg Tablet:

• Avoid consuming alcohol during the medication period as it may increase the risk of side effects and affect the absorption of Cephradine.
• Grapefruit and grapefruit juice should be consumed with caution as they can affect the metabolism of the drug, leading to increased drug levels in the body.
• Dairy products like milk and yogurt might interfere with the absorption of Cephradine, so consider separating their intake from medication timing.
• Avoid high-fat meals as they may delay the absorption of Cephradine, potentially affecting its effectiveness.
• Antacids containing aluminum or magnesium can reduce the absorption of Cephradine, so take them at least 2 hours apart.
• Vitamin and mineral supplements, especially those containing calcium and iron, may interact with Cephradine, so consult your doctor for proper timing.
• Caffeinated beverages might increase the elimination of Cephradine, so monitor your intake to ensure optimal drug levels.
• Always follow the instructions provided by your healthcare provider regarding specific dietary restrictions or recommendations during the medication period.

Cephradine 500mg Tablets should be stored in a cool, dry area, ideally at room temperature, ensuring protection from light and moisture. It is crucial to keep the medication in its original packaging, securely sealed to maintain its integrity. Avoid placing it in bathrooms or near heat sources like heaters, as temperature fluctuations can impact its effectiveness. Dispose of any unused or expired tablets responsibly; refrain from flushing them down the toilet or discarding them in sinks. Contact your pharmacist or healthcare professional for guidance on proper disposal methods. Always exercise caution to store medications out of children's reach to prevent accidental consumption.

Following are the quick tips for Cephradine 500mg Tablet:

• Take the tablet as directed by your doctor, typically every 6 to 12 hours.
• Ensure you complete the full prescribed course, even if you feel better.
• Swallow the tablet whole with a full glass of water; do not crush or chew.
• Take it with food to reduce stomach upset.
• Avoid alcohol consumption as it may interfere with the medication's effectiveness.
• If you miss a dose, take it as soon as you remember, unless it's almost time for the next dose.
• Store the medication at room temperature, away from moisture and heat.