SLOZEM 120MG "DILTIZEM HYDRO"

Diltiazem 120mg tablets primarily work by inhibiting calcium channels in the heart and blood vessels. This mechanism of action is crucial in treating cardiovascular conditions. By blocking the entry of calcium ions into cardiac and vascular smooth muscle cells, diltiazem relaxes these muscles, leading to a reduction in myocardial contractility, heart rate, and blood vessel constriction. This relaxation effect decreases blood pressure and improves blood flow, making it valuable in managing hypertension and angina pectoris. The calcium channel-blocking property of diltiazem is central to its therapeutic benefits, allowing for better control of cardiovascular functions without significantly impacting the heart's conduction system.

Diltiazem 120mg

Calcium channel blocker.

Tablet

The following are the uses of Diltiazem 120mg Tablet:

• Used for managing high blood pressure, helping to lower and control hypertension.
• Used for treating angina, providing relief from chest pain and discomfort associated with heart issues.
• Used to regulate irregular heart rhythms, including atrial fibrillation, to restore a normal heartbeat.
• Used to improve blood flow and reduce the workload on the heart, easing cardiovascular strain.
• Used in the prevention of migraines, helping to reduce the frequency and severity of attacks.
• Used for treating Raynaud's phenomenon, alleviating symptoms like cold fingers and toes.
• Used to manage certain heart conditions, such as hypertrophic cardiomyopathy, by relaxing the heart muscle.
• Used as a long-term treatment option for maintaining cardiovascular health and preventing complications.

In the case of an overdose of Diltiazem 120mg Tablets, it is important to recognize the potential symptoms, which may include severe dizziness, slow heartbeat, and difficulty breathing. Prompt action is necessary, including contacting a poison control center or seeking emergency medical care. Quick response can help manage the overdose effectively, ensuring the best possible outcome. It is crucial to act swiftly and not delay seeking professional assistance when dealing with such situations.

In the case of a missed dose of Diltiazem 120mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, consult your healthcare professional for guidance on how to safely resume your medication regimen. It is recommended to establish a routine to help you remember to take your medication as prescribed.

To take Diltiazem 120mg Tablets, swallow the tablet whole with a glass of water, preferably at the same time each day, following the instructions provided by your healthcare professional, typically once or twice daily, without crushing or chewing the tablet.

Here are the circumstances when Diltiazem 120mg Tablet should not be administered:

• Avoid using if you have a known allergy to Diltiazem or other similar calcium channel blockers.
• Not recommended for individuals with severe low blood pressure (hypotension).
• Do not use if you have a heart condition called 'AV block' (second or third degree) or sick sinus syndrome.
• Contraindicated in patients with a heart rhythm disorder called 'Ventricular Tachycardia'.
• Should not be used in individuals with severe liver disease or impaired liver function.
• Avoid using if you have recently had a heart attack and have low blood pressure, slow heart rate, or heart failure.
• Not suitable for individuals with a rare heart condition called 'QT prolongation' or an abnormal heart rhythm called 'Torsades de Pointes'.

The side effects of Diltiazem 120mg Tablet may include:

• Dizziness or lightheadedness
• Fatigue or weakness
• Headache
• Nausea and vomiting
• Constipation or stomach pain
• Slow heart rate (bradycardia)
• Swelling in legs or ankles
• Flushing or skin rash

Following are the precautions and warnings:

• Diltiazem 120mg Tablet should not be used in patients with a known allergy or sensitivity to diltiazem or other calcium channel blockers.
• This medication can cause a significant drop in blood pressure, so patients with hypotension or unstable angina should exercise caution and be closely monitored.
• Diltiazem may affect heart rhythm, so patients with heart conditions such as sick sinus syndrome, second or third-degree AV block, or severe aortic stenosis should use it with caution and under medical supervision.
• It can impact liver function; therefore, patients with liver disease or impaired liver function should be monitored regularly for potential liver-related side effects.
• Patients with kidney problems should use Diltiazem with caution, as dosage adjustments may be necessary for those with renal impairment.
• This medication can interact with other drugs, including beta-blockers, digoxin, and certain antifungal medications, so healthcare professionals should be informed about all medications the patient is taking.
• Diltiazem may cause dizziness or lightheadedness, so patients should avoid activities that require mental alertness, such as driving or operating heavy machinery, until they know how the medication affects them.
• Pregnant and breastfeeding women should consult their doctor before taking Diltiazem, as it may have potential risks for the fetus or infant.

Following are the drug interactions for Diltiazem 120mg Tablet:

• Co-administration with beta-blockers can cause bradycardia and severe hypotension.
• Combining with other calcium channel blockers may lead to increased risk of hypotension and bradycardia.
• Diltiazem can increase levels of digoxin, requiring close monitoring of digoxin levels.
• Concomitant use with statins can increase the risk of rhabdomyolysis.
• It may elevate blood levels of Cyclosporine, Tacrolimus, and Sirolimus, necessitating dosage adjustments.
• Diltiazem can reduce the effectiveness of antihypertensive agents like ACE inhibitors and diuretics.
• Caution is advised when combining with antiarrhythmic drugs due to potential additive effects on the heart.

Following are the food interactions for Diltiazem 120mg Tablet:

• Grapefruit and grapefruit juice should be consumed with caution as they can increase the levels of Diltiazem in the blood, potentially leading to increased side effects, particularly affecting heart rate and blood pressure.
• Alcohol intake should be minimized or avoided as it can cause a significant drop in blood pressure, especially when combined with Diltiazem, leading to dizziness and lightheadedness.
• High-fat meals can slightly delay the absorption of Diltiazem, but they do not significantly alter its effectiveness.
• Avoid excessive caffeine consumption as it can increase heart rate and counteract the effects of Diltiazem.
• Foods rich in potassium, such as bananas and oranges, should be consumed in moderation as Diltiazem can cause potassium levels to rise.
• Avoid eating large amounts of fiber-rich foods simultaneously as Diltiazem, as this may affect the absorption of the medication.
• Herbal supplements like St. John's Wort should be used cautiously as they can reduce Diltiazem's effectiveness.
• Always ensure you are well-hydrated when taking Diltiazem to prevent potential side effects related to dehydration.

Diltiazem 120mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring it is kept away from direct exposure to sunlight, heat, or moisture. The medication bottle should be tightly sealed to maintain its integrity and effectiveness. It is crucial not to store the tablets in the bathroom medicine cabinet due to the humidity, and avoid placing them near the kitchen stove or other heat-emitting appliances. Always check the expiration date, and dispose of any unused or expired tablets responsibly. Do not flush them or throw them into the trash; instead, follow local guidelines or consult a pharmacist for safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Diltiazem 120mg Tablet:

• Take the tablet as directed by your doctor, typically 1-4 times daily.
• Swallow the tablet whole with a full glass of water, do not crush or chew.
• Maintain a consistent dosing schedule to ensure stable blood levels.
• Avoid grapefruit juice and alcohol as they may affect the medication's effectiveness.
• Inform your doctor about all medications you're taking to prevent interactions.
• Store the tablets at room temperature, away from moisture and light.
• Do not share your medication with others, even if they have similar symptoms.