SOMAZINA 500MG INJ (CITICOLIN)

SOMAZINA 500MG INJ (CITICOLIN)

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  • Manufacturer FERRER INTEECIONAL S.A
  • Generic Name

    Citicoline 500mg

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Citicoline 500mg Injection primarily acts as a cognitive enhancer and neuroprotective agent. Its mechanism of action involves multiple pathways in the brain. Citicoline increases the synthesis of phosphatidylcholine, a major component of neuronal membranes, which helps in membrane repair and restoration. It also enhances neurotransmitter synthesis, particularly dopamine and norepinephrine, by providing the precursor choline. This leads to improved neuronal communication and neurotransmission. Citicoline promotes the production of brain-derived neurotrophic factor (BDNF), which supports neuronal survival, growth, and plasticity. Additionally, it exhibits antioxidant properties, reducing oxidative stress and protecting neurons from damage caused by free radicals. By influencing these various mechanisms, Citicoline supports overall brain health, enhances cognitive function, and aids in the recovery of damaged neurons.

  • Ingredients

    Citicoline 500mg

  • Drug Class

    Cholinergic, Nootropic

  • Dosage Form

    Injection

  • Uses

    The following are the uses of Citicoline 500mg Injection:

    • Used for improving brain function and memory, especially in elderly individuals with cognitive decline.
    • Used for treating neurological disorders like Alzheimer's disease and dementia.
    • Used for enhancing cognitive performance in those with brain injuries or stroke.
    • Used for supporting recovery after brain surgeries or traumatic brain injuries.
    • Used for managing symptoms of Parkinson's disease.
    • Used for reducing side effects of certain medications on brain health.
    • Used for promoting brain health and reducing mental fatigue in healthy adults.
  • In case of Overdose

    In the case of an overdose of Citicoline 500mg Injection, it is important to seek medical advice promptly. Overdosing on this medication may lead to adverse effects such as nausea, vomiting, dizziness, and headaches. The severity of symptoms can vary depending on the individual and the amount ingested. If you suspect an overdose, contact a healthcare professional or poison control center for guidance on the appropriate course of action. Prompt medical attention can help manage any potential complications.

  • Missed Dose

    In the case of a missed dose of Citicoline 500mg Injection, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare professional for guidance on how to get back on track with your medication regimen. It is advisable to set reminders to help you remember to take your medication as prescribed.

  • How To Use

    To administer Citicoline 500mg Injection, ensure the injection is at room temperature, clean the injection site with an alcohol swab, insert the needle at a 90-degree angle, and slowly inject the prescribed dose subcutaneously, following the instructions provided by your healthcare professional.

  • When Not to Use

    Following are the conditions or circumstances when Citicoline 500mg Injection should not be taken:

    • Should not be used in individuals with a known allergy to Citicoline or any of its components.
    • Not suitable for patients with severe kidney or liver impairment.
    • Contraindicated in individuals with a history of seizures or epilepsy, as it may lower the seizure threshold.
    • Not recommended for patients with severe bleeding disorders or those taking anticoagulant medications.
    • Should be avoided in individuals with a history of hypersensitivity reactions to any injectable medications.
    • Do not use if there is a known or suspected brain hemorrhage or severe head trauma.
    • Contraindicated in patients with a history of skin reactions or severe skin disorders.
  • Side Effects

    The side effects of Citicoline 500mg Injection may include:

    • Headache
    • Confusion
    • Diarrhea
    • Nausea and vomiting
    • Insomnia
    • Dizziness
    • Changes in blood pressure
    • Allergic reactions (skin rash, itching, swelling)
  • Precautions & Warnings

    Following are the precautions and warnings for Citicoline 500mg Injection:

    • Not recommended for individuals with a known allergy to Citicoline or any of its excipients.
    • Patients with a history of severe renal or hepatic impairment should exercise caution, and the dosage may need adjustment under medical supervision.
    • This medication may cause mild gastrointestinal symptoms like nausea or upset stomach; consider medical advice if these symptoms persist or worsen.
    • Patients with epilepsy or a history of seizures should consult a doctor before using this medication as it may influence seizure thresholds.
    • Citicoline injection should be administered under medical supervision; ensure proper technique to avoid injection site reactions.
    • Not intended for long-term use; consult a healthcare professional for the appropriate duration of treatment.
    • The safety and efficacy of Citicoline in pregnant and breastfeeding women have not been well-established; consult a doctor for advice.
  • Drug Interactions

    Following are the drug interactions for Citicoline 500mg Injection:

    • Citicoline may interact with medications that affect cholinergic systems, such as acetylcholinesterase inhibitors, potentially causing excessive cholinergic effects.
    • Concomitant use with anticholinergic drugs may reduce the effectiveness of Citicoline.
    • It can interact with neuroprotective agents, potentially affecting their efficacy.
    • Citicoline may influence the action of dopamine-related medications.
    • Caution is advised when using with drugs that impact cerebral blood flow, as it may alter their effects.
    • It could potentially interact with medications metabolized by certain liver enzymes, altering their effectiveness.
    • Citicoline's impact on cognitive function may interact with medications used for cognitive disorders.
  • Food Interactions

    Following are the food interactions for Citicoline 500mg Injection:

    • Avoid consuming alcohol during the treatment with Citicoline as it may increase the risk of side effects, particularly drowsiness and dizziness.
    • Grapefruit and grapefruit juice should be consumed with caution as they can affect the absorption and metabolism of Citicoline, potentially leading to increased drug levels in the body.
    • High-fat meals may delay the absorption of Citicoline, so it is advisable to take the medication on an empty stomach or with a light meal to ensure optimal absorption.
    • Caffeine intake should be monitored as it can potentially interact with Citicoline, affecting its effectiveness. It is best to limit or avoid excessive caffeine consumption.
    • Avoid energy drinks or high-sugar beverages as they may interfere with the therapeutic effects of Citicoline and potentially lead to increased side effects.
    • Maintain a balanced diet rich in essential nutrients to support overall brain health and optimize the benefits of Citicoline treatment.
    • Certain herbal supplements, such as Ginkgo Biloba, may interact with Citicoline, so it's advisable to consult a healthcare professional before combining them.
    • Always follow the advice of your healthcare provider regarding any specific dietary restrictions or recommendations during Citicoline therapy.
  • Storage/Disposal

    Citicoline 500mg Injection should be stored in a controlled room temperature environment, typically between 20°C and 25°C (68°F to 77°F), away from direct sunlight and moisture. It is crucial to keep the injection in its original packaging, tightly sealed, to maintain its sterility and prevent contamination. Avoid exposing the injection to freezing temperatures or extreme heat, as it may affect its potency. Always check the expiration date on the packaging, and do not use the injection if it is expired. For disposal, do not throw it in the trash or pour it down the drain. Contact your healthcare provider or pharmacist for instructions on safe disposal methods to protect the environment and prevent misuse. Keep the injection out of the sight and reach of children to ensure their safety.

  • Quick Tips, if any

    Following are the quick tips for Citicoline 500mg Injection:

    • Ensure the injection is administered by a trained healthcare professional for safety.
    • Verify the medication's label for dosage accuracy before administration.
    • For intravenous use, inject slowly over 3-5 minutes to minimize discomfort.
    • If using the intramuscular route, rotate injection sites to reduce pain.
    • Do not mix Citicoline with other medications unless instructed by your doctor.
    • Store the injection at room temperature, away from direct sunlight and moisture.
    • Dispose of used needles and syringes safely in designated sharps containers.

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