SPASMO CIBALGIN TAB

Hexahydroadiphenine and propyphenazone are both analgesic and antipyretic components of the combination drug. Hexahydroadiphenine is a synthetic opioid analgesic that acts on the central nervous system to relieve pain. It is believed to work by binding to opioid receptors, particularly the mu-opioid receptors, in the brain and spinal cord, reducing the perception of pain signals. Propyphenazone, on the other hand, is a non-opioid analgesic and antipyretic. It inhibits the synthesis of prostaglandins, which are involved in pain and inflammation processes, thereby reducing pain and fever. This dual mechanism of action provides synergistic effects, enhancing the analgesic and antipyretic properties of the combination.

Hexahydroadiphenine, Propyphenazone

Antihistamine, Analgesic

Tablet

The following are the uses of Hexahydroadiphenine, Propyphenazone Tablet:

• Used for relieving mild to moderate pain, including headaches, toothaches, and post-surgical pain.
• Used for reducing fever and managing symptoms of cold and flu.
• Used for its anti-inflammatory properties to reduce swelling and inflammation.
• Used for providing short-term relief from acute painful conditions.
• Used for managing pain and discomfort associated with musculoskeletal disorders.
• Used for treating symptoms of migraine and providing temporary relief.
• Used for alleviating discomfort and inflammation in minor injuries.

In the case of an overdose of Hexahydroadiphenine and Propyphenazone Tablets, individuals may experience symptoms such as nausea, vomiting, dizziness, and in severe cases, respiratory depression or seizures. Promptly seek medical assistance and provide healthcare professionals with detailed information about the medication, the amount ingested, and any observed symptoms. Quick action can help mitigate potential health risks and ensure appropriate treatment.

In the case of a missed dose of Hexahydroadiphenine and Propyphenazone Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It's important to maintain a consistent medication routine, but if you have concerns, consult your healthcare provider for specific guidance.

To take the Hexahydroadiphenine, Propyphenazone Tablet, swallow the tablet whole with a full glass of water, following the dosage instructions provided by your healthcare professional, typically one tablet every 4-6 hours as needed, without chewing or crushing the tablet.

Following are the conditions when Hexahydroadiphenine and Propyphenazone Tablet should not be used:

• Not recommended for individuals with a known allergy or hypersensitivity to either Hexahydroadiphenine, Propyphenazone, or any other related compounds.
• Contraindicated in patients with severe liver or kidney impairment.
• Should be avoided in individuals with a history of gastrointestinal bleeding or obstruction.
• Not suitable for patients with a history of bronchial asthma or other respiratory disorders.
• Must not be used in individuals with a history of agranulocytosis or bone marrow depression.
• Contraindicated during pregnancy and breastfeeding.
• Should be used with caution and avoided in children under 12 years of age.
• Avoid if there is a history of alcohol abuse or dependency.
• Not recommended for patients with a history of porphyria.
• Should not be used in patients with a history of seizures or epilepsy.

The side effects of Hexahydroadiphenine, Propyphenazone Tablet may include:

• Drowsiness or sedation
• Nausea and vomiting
• Stomach pain or discomfort
• Dry mouth
• Constipation
• Allergic reactions, such as skin rash or itching
• Dizziness or lightheadedness
• Difficulty in urination

Following are the precautions and warnings for Hexahydroadiphenine, Propyphenazone Tablet:

• Individuals with known allergies to either Hexahydroadiphenine or Propyphenazone should not take this medication.
• Patients with a history of liver or kidney problems should exercise caution and consult a healthcare professional, as these conditions may require dosage adjustments.
• Avoid alcohol consumption while taking this medication, as it may intensify the sedative effects.
• Do not operate heavy machinery or drive if you experience dizziness or sleepiness after taking this tablet.
• This medication is not recommended for children, and elderly patients should use it with caution and under medical supervision.
• Pregnant and breastfeeding women should consult their doctor before taking this medication, as its safety during pregnancy and lactation is not well established.
• Inform your healthcare provider about all the medications you are currently taking to avoid potential drug interactions.
• Store the tablets in a cool, dry place, away from direct sunlight, and keep them out of the reach of children.

Following are the drug interactions for Hexahydroadiphenine, Propyphenazone Tablet:

• Alcohol and other central nervous system (CNS) depressants may have additive effects, leading to increased drowsiness and sedation.
• It may interact with anticoagulants, potentially affecting blood clotting and increasing the risk of bleeding.
• The effectiveness of contraceptive pills may be reduced when taken with this medication.
• Hexahydroadiphenine may increase the effects of antihypertensive drugs, causing excessive blood pressure drop.
• Propyphenazone can enhance the anticoagulant effect of warfarin, requiring close monitoring.
• Combining with other analgesics, especially opioids, may lead to respiratory depression and increased risk of overdose.
• Caution is advised with drugs metabolized by the liver, as this combination may affect liver enzyme activity.

Following are the food interactions for Hexahydroadiphenine, Propyphenazone Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can interfere with the metabolism of the medication, potentially leading to increased drug levels in the body.
• Alcohol should be consumed with caution as it may enhance the sedative effects of the medication, causing increased drowsiness and dizziness.
• Fatty foods may slightly delay the absorption of the medication but are generally not a concern.
• Caffeine-rich beverages like coffee and tea may reduce the effectiveness of the medication, as caffeine can impact the drug's metabolism.
• Avoid high-sodium foods as Propyphenazone can increase sodium retention, and excessive sodium intake should be monitored.
• It is advisable to maintain a balanced diet and drink plenty of fluids to prevent dehydration, especially if you experience sweating or diarrhea.
• Always consult your healthcare provider for specific dietary recommendations based on your medical condition and medication regimen.

Hexahydroadiphenine, Propyphenazone Tablets should be stored in a cool and dry environment, preferably at room temperature, ensuring protection from light and moisture. Keep the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. It is crucial to adhere to proper disposal practices for any unused or expired medication. Avoid flushing or discarding them in household waste; instead, consult your pharmacist or healthcare professional for guidance on safe disposal methods. Always exercise caution to keep medications out of the reach of children to prevent accidental consumption.

Following are the quick tips for Hexahydroadiphenine, Propyphenazone Tablet:

• Consult a doctor or pharmacist before use if you have any underlying medical conditions or are taking other medications.
• Take the tablet as directed by your healthcare professional for best results.
• Swallow the tablet whole with a full glass of water, do not crush or chew.
• Maintain a consistent dosing schedule for maximum effectiveness.
• Avoid driving or operating machinery if the medication causes drowsiness.
• Inform your doctor if you experience any unusual symptoms or allergic reactions.
• Store the medication in a cool, dry place, away from direct sunlight.