Spersallerg (0.4/0.5mg) 10ml Eye Drops

Antazoline drops, a first-generation antihistamine, exert their effect primarily by antagonizing histamine H1 receptors. The active ingredient, antazoline, competitively binds to these receptors, preventing histamine from interacting with them. This action inhibits the histamine-induced response, particularly in the conjunctiva and ocular tissues. By blocking H1 receptors, antazoline reduces the itching, redness, and inflammation associated with allergic reactions, providing relief from symptoms such as itchy and watery eyes. This mechanism is crucial in managing various allergic conjunctivitis conditions, where histamine release is a key contributor to the discomfort and irritation experienced by patients.

Antazoline

Antihistamine

Drop

The following are the uses of Antazoline Drop:

• Used for relieving symptoms of allergic conjunctivitis, such as itchy and watery eyes.
• Used for treating eye allergies caused by pollen, dust, or pet dander.
• Used to provide temporary relief from eye irritation and redness.
• Used for reducing eye discomfort associated with allergies.
• Used for preventing further eye irritation during allergy season.
• Used for its antihistamine properties to block the effects of histamine, a chemical released during allergic reactions.
• Used for its effectiveness in both adults and children, offering quick and localized relief.

In the case of an overdose of Antazoline Drops, it is important to remain calm and take swift action. First, contact your local poison control center or seek emergency medical assistance. Provide them with details about the medication, including the dosage and time of ingestion. They will guide you on the necessary steps, which may include inducing vomiting or administering specific treatments to counteract the effects of the overdose. Prompt action is vital to ensure the best possible outcome.

In the case of a missed dose of Antazoline Eye Drops, it is important to administer the medication as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss several doses, contact your healthcare provider for advice on how to proceed and to determine if any adjustments to your treatment plan are necessary.

To use Antazoline Drops, gently tilt your head back, instill the prescribed number of drops into the affected eye(s), and then close your eyes for a minute to ensure the medication is absorbed.

Following are the conditions/situations when Antazoline Eye Drops should not be used:

• Should not be used if you are allergic to any of the ingredients in the eye drops, including antazoline and xylometazoline.
• Not suitable for individuals with narrow-angle glaucoma or untreated open-angle glaucoma.
• Contraindicated in patients with severe dry eye syndrome or severe corneal disease.
• Should not be used if you have a history of hypersensitivity or allergic reactions to similar medications.
• Avoid using these eye drops if you have recently undergone eye surgery or have any eye injury or infection.
• Not recommended for infants or young children without medical advice.
• Discontinue use if you experience severe eye pain, changes in vision, or increased eye redness.

The side effects of Antazoline Eye Drops may include:

• Allergic reactions (skin rash, itching, swelling)
• Increased heart rate or palpitations
• Drowsiness or sedation
• Dry mouth
• Blurred vision or difficulty focusing
• Eye irritation or redness
• Headache
• Nausea

Following are the precautions and warnings for Antazoline Eye Drops:

• Do not use if you are allergic to any of its ingredients; check the package insert for a complete list.
• Remove contact lenses before application and wait at least 15 minutes after use before reinserting them.
• Do not touch the dropper tip to any surface, including the eye, to avoid contamination.
• Discontinue use and consult a doctor if symptoms persist or worsen after 2-3 days of treatment.
• May cause blurred vision; avoid driving or operating machinery until you know how the medication affects you.
• Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.
• Consult a healthcare professional if you have a history of eye diseases or are using other eye medications.

Following are the drug interactions for Antazoline Drops:

• Alcohol may cause increased drowsiness or dizziness when used with Antazoline.
• Antazoline may interact with antidepressants like monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants, potentially leading to increased side effects.
• Drugs that cause drowsiness, such as opioids, antihistamines, or benzodiazepines, may have additive sedative effects.
• Antazoline can interact with anticholinergic medications, possibly causing increased dry mouth, blurred vision, and urinary retention.
• When combined with other medications that affect the heart, such as beta-blockers or antiarrhythmics, it may lead to increased cardiovascular side effects.
• Certain antibiotics, like erythromycin, may inhibit the metabolism of Antazoline, resulting in higher drug levels and increased side effects.
• Antazoline may impact the effectiveness of glaucoma medications, requiring close monitoring of intraocular pressure.

Following are the food interactions for Antazoline Drops:

• Alcohol consumption should be avoided as it can increase the sedative effects, causing dizziness and drowsiness.
• Grapefruit and its juice should be restricted as they may elevate Antazoline levels in the blood, potentially increasing side effects.
• Caffeine intake should be monitored as it can enhance the stimulant effects of Antazoline, leading to increased heart rate and blood pressure.
• Avoid fatty meals as they may delay the absorption of Antazoline, affecting its onset of action.
• Spicy foods are best consumed in moderation as they can irritate the stomach and potentially reduce the effectiveness of Antazoline in treating stomach-related conditions.
• Ensure adequate hydration, as Antazoline may cause dry mouth and drinking water can help alleviate this side effect.
• Certain dairy products may interact, so consult your healthcare provider for specific dietary guidelines.
• Always adhere to the dosage instructions provided by your healthcare professional for optimal results.

Antazoline eye drops should be stored in a cool, dry place, preferably at room temperature between 15-25°C (59-77°F). Keep the bottle tightly closed when not in use to prevent contamination. Avoid exposing the drops to direct sunlight or freezing temperatures as it may affect their potency. Always check the expiration date and do not use the drops if they have expired. Dispose of any unused or expired medication responsibly by following local guidelines or consulting a pharmacist. Do not pour the drops down the sink or flush them down the toilet; instead, seek advice on appropriate disposal methods. Keep the medication safely out of children's reach to prevent accidental exposure.

Following are the quick tips for Antazoline Drops:

• Wash your hands before using the eye drops to maintain hygiene.
• Tilt your head back, gently pull down your lower eyelid, and instill the prescribed number of drops into the eye.
• Avoid touching the dropper tip to your eye or any surface to prevent contamination.
• Close your eyes gently and apply light pressure to the inner corner of the eye for a few minutes to minimize drug absorption into the bloodstream.
• If you are using other eye medications, wait at least 5-10 minutes before applying the next medication to prevent washout.
• Do not wear contact lenses while using these drops unless advised by your doctor.
• Store the drops in a cool, dry place, away from direct sunlight and heat.