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  • Manufacturer Aspin Pharma (Pvt.) Ltd.
  • Generic Name

    Itraconazole 100mg

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Storage/Disposal
  • Description

    Itraconazole is a man-made drug that helps treat fungal infections. It is classified as an azole-type drug and interferes with the fungal cell membrane. It also inhibits the enzyme lanosterol demethylase which is crucial for the production of ergosterol, a significant component of the fungal cell membrane. Itraconazole's mechanism of action leads to the fungus' death by disrupting the integrity of the fungal cell membrane. This drug is often used to treat various fungal infections, including aspergillosis, blastomycosis, candidiasis, and histoplasmosis. It is taken orally as a tablet or capsule, and the dosage range is from 100 to 200 mg per day, depending on the severity of the infection and the type of fungus being treated. Itraconazole is effective against fungal infections because it interferes with the fungal cell membrane and inhibits specific enzymes. However, it is not effective against all types of fungal organisms, so it is not a universal solution for fungal infections.

  • Ingredients

    Itraconazole 100mg

  • Drug Class

    Antifungals

  • Dosage Form

    Capsule

  • Uses

    Itraconazole is utilized for the following therapeutic indications:

    • Treatment of fungal infections, including systemic mycoses
    • Effective against dermatophyte infections, such as athlete's foot and ringworm
    • Used for onychomycosis (fungal nail infection)
    • Treatment of candidiasis, including oropharyngeal and esophageal candidiasis
    • May be indicated for the prevention of fungal infections in immunocompromised patients
    • Active against various species of Aspergillus in certain clinical settings
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Treatment of Aspergillus infection - 100-200 mg daily (divided bid to qid) for 2-4 weeks
    • Treatment of yeast infections - 200 mg daily for 6 weeks
    • Pulse treatment of fungal infections - 800 mg daily for 1 day, followed by 400 mg once daily for 4 days in combination with amphotericin B
    • Prophylaxis of invasive aspergillus - 200-400 mg daily (po or iv)
    • Safe and effective dose for prophylaxis of P. Aeruginosa pneumonia - 400 mg once daily
  • In case of Overdose

    Itraconazole is a prescription drug that is primarily used to treat fungal infections. It is noteworthy that Itraconazole is a potent anti-fungal agent and accidental overdose is unlikely to occur. However, an overdose of Itraconazole may lead to severe gastrointestinal symptoms such as nausea, vomiting, and abdominal pain. In severe cases, liver injury, heart problems, or even death may occur. If you believe you have overdosed on Itraconazole, it is essential to seek immediate medical attention from a healthcare provider. Providing information on any substance(s) ingested or utilised in the overdose can assist doctors in treating you efficiently. You will receive supportive care under the supervision of healthcare professionals, which may include monitoring vital signs, addressing any complications, and, in some instances, using specific medications to alleviate the symptoms of overdose. Moreover, providing information on the amount and time frame of Itraconazole consumption can assist healthcare providers in determining the severity of the overdose and establishing the appropriate treatment strategy.

  • Missed Dose

    Itraconazole is a medication used to treat fungal infections, and it is important to take it as directed to ensure the best results. If you miss a dose, you should take it as soon as possible. If it is almost time for your next dose, you should skip the missed dose and continue with your regular schedule. To avoid doubling up on doses, refer to the instructions from the pharmacist or doctor who prescribed the medication, or contact your doctor or pharmacist for advice. It is essential to complete the full course of treatment as prescribed by your doctor to prevent the development of resistance. Itraconazole is a potent drug, and it is important to follow the recommended dosage and usage instructions to avoid any potential side effects. With prompt and consistent use, along with following the instructions carefully, itraconazole can be an effective means to treat fungal infections and promote a faster recovery.

  • How To Use

    Itraconazole is a medication that is typically taken orally in the form of a tablet, capsule, or liquid suspension. Before starting this medication, it is important to read the medication guide provided by the manufacturer or your doctor, as it contains vital information about the uses, side effects, and precautions to take while on it. Itraconazole is usually taken once or twice a day with or without food, as directed by a medical professional. The dosage and duration of treatment will depend on the condition being treated and the individual's response to the medication. For those who have difficulty swallowing, the tablet or capsule can be taken whole or opened, and the contents can be mixed with a small amount of food or liquid to make it easier to swallow. If taking the liquid suspension, it is important to shake the bottle well before each use to ensure the medication is evenly dispersed. Measuring the liquid carefully with the provided dose-measuring cup or spoon is crucial to ensure the correct dose is consumed. Itraconazole should be stored in a cool, dry place, away from direct heat and light. It should not be stored in the bathroom or near a sink, and should be kept out of reach of children and pets. If a dose is missed, it is recommended to take it as soon as possible, unless it is almost time for the next scheduled dose. In this case, it is advised to skip the missed dose and continue with the regular schedule. Doubling up on the medication to make up for a missed dose should be avoided. Itraconazole may cause side effects in some people, with the most common being nausea, vomiting, diarrhea, and abdominal pain. These side effects may subside as the body adjusts to the medication, but if they persist or worsen, it is important to notify your doctor. Other side effects may also occur, so caution is necessary while taking this medication.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • If you are allergic to it or any of the other ingredients in the formulation.
    • If you have any underlying kidney conditions or a history of kidney problems.
    • If you have any conditions that affect your gut function, such as ulcerative colitis or Crohn's disease.
    • If you are taking any medications that are substrates of CYP3A4.
    • If you have a history of bone marrow suppression or decreased immune cell counts.
    • If you have had recent surgery or injury.
    • If you have an active infection.
    • If you have visual abnormalities such as retinal lesions or glaucoma.
    • If you have significant liver disease or a history of liver failure with Itraconazole.
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Kidney impairment/failure
    • Hepatitis
    • Pancreatitis
    • Jaundice
    • Skin disorders
    • Eye disorders
    • Gastrointestinal disturbances
    • Liver dysfunction
    • Respiratory disorders
    • Neurological disorders
    • Appetite loss
    • Weight loss
    • Nightmares
    • Serotonin syndrome
    • Agitation
    • Confusion
  • Storage/Disposal

    Itraconazole is a medication that should be stored at room temperature, away from moisture, heat, and direct sunlight. The medication should be kept in its original container and kept in a location that is out of the reach of children and pets. Exposure to light and moisture can affect the medication's effectiveness, which is why it should be kept in a sealed environment. When not in use, the original container will ensure the medication's stability and help maintain its quality. If you have any specific questions or concerns about storing Itraconazole 100mg, it is important to consult your physician or pharmacist. They are the best sources to provide you with guidance that is tailored to your personal situation, regarding the storage of your medication.

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