STADOL 1MG 1ML INJ

Butorphanol, a synthetic agonist-antagonist opioid, exerts its effects by interacting with opioid receptors in the central nervous system. It acts as a partial agonist at the kappa-opioid receptors and as an antagonist at the mu-opioid receptors. This dual action results in analgesia, where butorphanol can provide pain relief by activating kappa receptors, while also reducing some of the unwanted side effects associated with full mu-opioid agonists. The kappa receptor activation is believed to contribute to the drug's analgesic properties, while the mu receptor antagonism may help mitigate respiratory depression and other typical opioid-related adverse effects.

BUTORPHANOL 1MG

Opioid analgesic

Injection

The following are the uses of BUTORPHANOL 1MG Injection:

• Used for treating moderate to severe pain, providing effective pain relief.
• Used for managing pain during medical procedures or post-surgery.
• Used for controlling pain in patients with chronic pain conditions.
• Used for alleviating pain associated with cancer and palliative care.
• Used for aiding in the management of pain during labor and childbirth.
• Used for reducing pain and discomfort in various acute pain scenarios.
• Used for providing a sedative effect, promoting patient comfort and relaxation.
• Used for certain veterinary applications, primarily for pain management in animals.

In the case of an overdose of BUTORPHANOL 1MG Injection, it is important to recognize the signs, which may include severe drowsiness, difficulty breathing, and impaired consciousness. If an overdose is suspected, seek emergency medical assistance immediately. The medical team should be informed about the medication and dosage taken, as well as any other relevant medical history. Prompt treatment can help manage the symptoms and prevent potential complications.

In the case of a missed dose of BUTORPHANOL 1MG Injection, it is important to administer the medication as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare professional for guidance on how to safely resume the medication. It is crucial to maintain a consistent dosing schedule for the medication's effectiveness.

To administer BUTORPHANOL 1MG Injection, ensure proper medical training, clean the injection site, and inject the entire contents of the vial intramuscularly or intravenously, following the prescribed dosage and administration guidelines provided by your healthcare professional.

Here are the situations when BUTORPHANOL 1MG Injection should not be used:

• Should not be administered to individuals with a known hypersensitivity or allergy to Butorphanol or any of the excipients in the injection.
• Contraindicated in patients with severe respiratory depression or asthma, as it may worsen breathing difficulties.
• Not recommended for individuals with acute abdominal conditions or increased intracranial pressure.
• Should not be used in patients with a head injury or intracranial lesions.
• Contraindicated during or immediately before and after surgery on the biliary tract.
• Not suitable for patients with severe central nervous system (CNS) depression or coma.
• Should not be administered to individuals with a known or suspected gastrointestinal obstruction.
• Contraindicated in patients with acute alcoholism or delirium trem.
• Not recommended for use in patients with convulsive disorders or epilepsy.

The side effects of BUTORPHANOL 1MG Injection may include:

• Dizziness
• Sedation or drowsiness
• Nausea and vomiting
• Confusion
• Dry mouth
• Constipation
• Respiratory depression
• Allergic reactions (skin rash, itching, swelling)

Following are the precautions and warnings for BUTORPHANOL 1MG Injection:

• Not recommended for use in patients with severe respiratory depression or asthma, as it may worsen breathing difficulties.
• Should be used with caution in patients with head injuries, increased intracranial pressure, or conditions affecting the central nervous system.
• Patients with liver or kidney impairment may require dosage adjustments, and close monitoring is necessary.
• Butorphanol may cause sedation and dizziness, so patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• Not recommended for use during pregnancy or breastfeeding unless the potential benefits outweigh the risks.
• Elderly patients may be more sensitive to the effects of butorphanol, and dosage adjustments might be needed.
• Butorphanol has the potential for abuse and dependence, and should be used with caution in patients with a history of substance abuse.
• Discontinue use and seek medical attention if signs of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, occur.

Following are the drug interactions for BUTORPHANOL 1MG Injection:

• May interact with central nervous system (CNS) depressants like benzodiazepines, alcohol, or other opioids, enhancing respiratory depression and sedation.
• Concurrent use with other opioid antagonists (e.g., naltrexone) can reduce the analgesic effect of butorphanol.
• Monoamine oxidase inhibitors (MAOIs) should be avoided due to the potential for serotonin syndrome.
• Butorphanol may increase the effects of anticoagulants, such as warfarin, leading to bleeding risks.
• The effectiveness of butorphanol may be reduced when used with mixed agonist/antagonist opioids like pentazocine.
• Certain medications metabolized by the liver, including some antiepileptic drugs, may have increased blood levels when taken with butorphanol.
• Drugs that affect liver enzymes, such as rifampicin, can alter the metabolism and effectiveness of butorphanol.

Following are the food interactions for BUTORPHANOL 1MG Injection:

• Avoid consuming grapefruit or grapefruit juice as it may interfere with the metabolism of BUTORPHANOL, potentially leading to increased drug levels in the body.
• Alcohol consumption should be minimized or avoided as it can enhance the sedative effects of BUTORPHANOL, increasing the risk of dizziness, drowsiness, and impaired coordination.
• Caffeine-rich beverages like coffee and energy drinks should be consumed in moderation as they may counteract the analgesic effects of BUTORPHANOL, reducing its effectiveness.
• Avoid high-fat meals as they can potentially delay the absorption of BUTORPHANOL, affecting the onset of its action.
• Spicy foods should be approached with caution as they may irritate the stomach and potentially exacerbate nausea, especially when combined with the use of BUTORPHANOL.
• Maintain a balanced diet to support overall health, ensuring adequate hydration and nutrition, which can aid in the body's response to medication.
• Consult your healthcare provider for specific dietary recommendations, especially if you have underlying health conditions that may require dietary adjustments while using BUTORPHANOL.
• No significant food interactions are known to directly impact the effectiveness of BUTORPHANOL, but individual responses may vary, so monitoring for any unusual reactions is advisable.

BUTORPHANOL 1MG Injection should be stored in a secure and controlled environment, preferably in a locked cabinet or a designated medication storage area. It should be kept at room temperature, away from excessive heat, direct sunlight, and moisture. The injection vials should remain sealed and intact until ready for use, ensuring the integrity of the medication. It is crucial to handle BUTORPHANOL with care, as it is a controlled substance, and proper disposal is essential. When disposing of unused or expired injections, follow local regulations and guidelines for pharmaceutical waste disposal. Do not dispose of the medication in regular trash or pour it down the drain; instead, contact a pharmacist or healthcare professional for guidance on safe disposal methods.

Following are the quick tips for BUTORPHANOL 1MG Injection:

• Administer the injection under medical supervision for safe and effective use.
• Ensure the injection is given intramuscularly or subcutaneously as directed.
• Do not inject intravenously unless specifically instructed by a healthcare professional.
• Rotate injection sites to minimize tissue irritation and damage.
• Dispose of used needles and syringes safely in designated sharps containers.
• If you experience dizziness, lie down until it passes to prevent injury.
• Store the injection as directed on the label, away from light and moisture.