Stenzar (2mg/5ml) 120ml Syrup

Cyproheptadine Syrup/Suspension primarily exerts its effects through its actions as a potent antihistamine and antiserotonergic agent. It competitively antagonizes histamine H1 receptors, effectively blocking the actions of histamine, which leads to the reduction of histamine-induced symptoms such as sneezing, itching, and nasal congestion. Additionally, cyproheptadine's antiserotonergic properties result from its ability to block serotonin (5-HT) receptors, particularly the 5-HT2 receptors, thereby inhibiting the actions of serotonin in various parts of the body. This dual action helps in managing conditions related to allergic reactions and certain types of headaches by reducing the effects of both histamine and serotonin.

Cyproheptadine

Antihistamine.

Suspension

The following are the uses of Cyproheptadine Syrup/Suspension:

• Used for treating allergic reactions and relieving symptoms like itching, hives, and skin rash.
• Used for managing allergic conjunctivitis, reducing eye inflammation and itching.
• Used for stimulating appetite in patients with significant weight loss due to medical conditions.
• Used for preventing and treating migraine headaches, providing relief from pain and associated symptoms.
• Used for treating mild to moderate pain, especially when combined with other analgesics.
• Used for controlling nausea and vomiting, particularly in post-operative cases or due to motion sickness.
• Used for alleviating symptoms of the common cold and upper respiratory tract infections.

In the case of an overdose of Cyproheptadine Syrup/Suspension, immediate medical attention is required. Symptoms may include severe drowsiness, confusion, dry mouth, and difficulty in breathing. Promptly seek emergency care and inform the healthcare provider about the medication and the estimated amount ingested. Quick action can help prevent potential complications and ensure appropriate treatment measures are taken to manage the overdose effectively.

In the case of a missed dose of Cyproheptadine Syrup/Suspension, it is important to act promptly. If you remember within a few hours of the missed dose, administer the medication as soon as possible. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. Consult your healthcare provider if you have any concerns or if you miss multiple doses.

To take Cyproheptadine Syrup/Suspension, shake the bottle well, measure the prescribed dose with a measuring device, and administer it orally, following the dosage instructions provided by your healthcare professional, typically taken twice a day, 12 hours apart, with or without food, as directed.

Here are the circumstances when Cyproheptadine Syrup/Suspension should not be administered:

• Avoid use in patients with a known hypersensitivity or allergy to Cyproheptadine or any of its ingredients.
• Not suitable for individuals with narrow-angle glaucoma.
• Contraindicated in patients who have recently had a heart attack.
• Should not be used in patients with severe high blood pressure or hypertension.
• Avoid use in individuals with a history of seizures or epilepsy.
• Not recommended for patients with an enlarged prostate, as it can worsen urinary retention.
• Contraindicated in patients with severe gastrointestinal obstruction or severe constipation.
• Not suitable for infants under 2 years of age.
• Should not be used in patients with severe central nervous system depression or coma.
• Avoid use in individuals with severe respiratory depression or asthma.

The side effects of Cyproheptadine Syrup/Suspension may include:

• Drowsiness or sedation
• Dry mouth and throat
• Blurred vision or temporary vision changes
• Constipation
• Increased appetite and weight gain
• Dizziness or lightheadedness
• Skin rash or hives
• Confusion or disorientation

Following are the precautions and warnings for Cyproheptadine Syrup/Suspension:

• Avoid use in patients with known hypersensitivity to cyproheptadine or any other components of the syrup.
• Use with caution in patients with glaucoma, as cyproheptadine may increase intraocular pressure.
• May cause drowsiness, dizziness, or blurred vision; avoid driving or operating heavy machinery while using this medication.
• Not recommended for use in children under 2 years of age unless prescribed by a healthcare provider.
• Patients with a history of urinary retention, prostate enlargement, or bladder obstruction should use with caution.
• May interact with other central nervous system depressants, including alcohol, sedatives, or tranquilizers; avoid concurrent use.
• Use with caution in patients with a history of asthma, respiratory disease, or bronchitis, as cyproheptadine can cause dryness of the mouth and throat.
• Monitor for potential weight gain, as cyproheptadine may stimulate appetite in some individuals.
• Patients with liver or kidney disease should consult a healthcare provider before use, as adjustments in dosage may be necessary.
• Pregnant or breastfeeding women should consult their healthcare provider before using this medication.
• Do not exceed the prescribed dose to avoid the risk of overdose and related side effects.

Following are the drug interactions for Cyproheptadine Syrup/Suspension:

• Alcohol and other central nervous system (CNS) depressants, such as benzodiazepines or opioids, can increase drowsiness and sedation when taken with this medication.
• Cyproheptadine may enhance the effects of anticholinergic drugs, leading to increased side effects like dry mouth, blurred vision, and constipation.
• It can reduce the effectiveness of antipsychotic medications, particularly phenothiazines.
• Antihistamines and other medications with anticholinergic properties may have additive effects when combined with Cyproheptadine.
• Monoamine oxidase inhibitors (MAOIs) should be avoided or used with caution due to the potential for increased side effects and serotonin syndrome.
• Drugs that prolong QT interval, like certain antiarrhythmics or antipsychotics, may increase the risk of cardiac arrhythmias when used concurrently.
• Cyproheptadine may decrease the efficacy of tricyclic antidepressants.

Following are the food interactions for Cyproheptadine Syrup/Suspension:

• Avoid consuming alcohol as it may increase the sedative effects and potentially cause excessive drowsiness or dizziness.
• Grapefruit and grapefruit juice should be consumed with caution as they can interfere with Cyproheptadine's metabolism, leading to increased levels in the blood and potential side effects.
• Avoid high-fat meals as they may delay the absorption of Cyproheptadine, affecting its onset of action.
• Caffeine-containing beverages like coffee and tea should be limited as Cyproheptadine can increase their effects, leading to heightened alertness or insomnia.
• Consuming foods rich in tyramine, such as aged cheeses, cured meats, and certain types of beer, should be avoided as Cyproheptadine may enhance their effects, potentially causing high blood pressure.
• Be cautious with spicy foods as Cyproheptadine may lower the tolerance for spicy flavors, leading to increased sensitivity.
• Always follow the dosage instructions provided by your healthcare professional, and ensure you take Cyproheptadine with a full glass of water for optimal absorption.
• Inform your doctor if you have any dietary restrictions or preferences to ensure the best possible treatment outcome.

Cyproheptadine Syrup/Suspension requires careful storage and disposal to maintain its integrity and prevent misuse. Store the medication in a cool, dry area, ideally at room temperature, shielded from sunlight and moisture. Ensure the container remains tightly sealed to prevent contamination. Avoid storage in bathrooms or near heat sources like stoves or radiators, as temperature fluctuations can impact the medicine's effectiveness. Prior to usage, inspect the packaging for the expiration date, and properly dispose of any unused or expired syrup. Do not dispose of it through the toilet or drainage systems; instead, consult a pharmacist or healthcare professional for appropriate disposal methods. Keep the medication securely stored, away from children, to eliminate the risk of accidental ingestion.

Following are the quick tips for Cyproheptadine Syrup/Suspension:

• Administer the medication as directed by your doctor or pharmacist.
• Ensure you understand the dosage instructions and duration of treatment.
• Shake the bottle well before each use to ensure proper mixing.
• Measure the dose accurately using the provided measuring device.
• Store the syrup/suspension at room temperature, away from excessive heat and moisture.
• Do not freeze the medication as it may affect its effectiveness.
• Regularly monitor your health and inform your doctor of any persistent or worsening symptoms.