Stilnox CR (6.25mg) 14 Tablets

Zolpidem tartrate 6.25mg tablets primarily work by enhancing the effects of a natural brain chemical called GABA (gamma-aminobutyric acid). This drug selectively binds to specific GABA receptors in the brain, particularly those located in the cerebral cortex, which are involved in sleep regulation. By binding to these receptors, zolpidem increases the efficiency of GABA, an inhibitory neurotransmitter, leading to a decrease in neuronal excitability. This action helps to induce sleep by slowing down certain brain activities, promoting relaxation, and reducing the time it takes to fall asleep. The selective binding of zolpidem to specific GABA receptors also contributes to its sedative effects while minimizing the impact on other cognitive functions, making it a targeted treatment for insomnia.

Nonbenzodiazepine Hypnotic

Tablet

The following are the uses of Zolpidem Tartrate 6.25mg Tablet:

• Used for treating insomnia by helping individuals fall asleep faster.
• Used to improve sleep quality and increase total sleep duration.
• Used to reset the sleep cycle, aiding those with irregular sleep patterns.
• Used to manage sleep disorders, ensuring more restful and uninterrupted sleep.
• Used to enhance overall sleep efficiency, reducing middle-of-the-night awakenings.
• Used to alleviate symptoms of jet lag, adjusting the body's sleep schedule.
• Used to support relaxation and promote a sense of calm before bedtime.
• Used as a short-term solution for sleep difficulties, providing temporary relief.

In the case of an overdose of Zolpidem Tartrate 6.25mg Tablets, individuals may experience symptoms such as extreme drowsiness, confusion, and impaired coordination. They may also exhibit slowed breathing, low blood pressure, and even loss of consciousness. Prompt medical intervention is essential, as overdose can lead to severe respiratory depression, which may be life-threatening. It is crucial to seek emergency medical care if an overdose is suspected, as timely treatment can mitigate potential complications and ensure the individual's safety.

In the case of a missed dose of Zolpidem Tartrate 6.25mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Avoid taking extra medicine to make up for a missed dose, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen.

To take Zolpidem Tartrate 6.25mg Tablet, simply place the tablet on your tongue and allow it to dissolve, preferably on an empty stomach, following the instructions provided by your healthcare professional for the recommended dosage and timing, ensuring a good night's rest.

Here are the conditions and situations when Zolpidem Tartrate 6.25mg Tablet should not be taken:

• Allergic reaction • Should not be used if you have a known allergy to Zolpidem or any of its ingredients.
• Sleep apnea • Contraindicated in individuals with untreated or uncontrolled sleep apnea.
• Severe liver impairment • Not recommended for patients with severe liver problems.
• Acute respiratory failure • Should not be used in patients with sudden or acute respiratory issues.
• Myasthenia gravis • Contraindicated in individuals with this neuromuscular disorder.
• Alcohol consumption • Avoid using Zolpidem if you have consumed alcohol, as it can increase the risk of side effects.
• Other CNS depressants • Should not be used concurrently with other central nervous system (CNS) depressant medications.
• Elderly patients • Zolpidem may not be suitable for elderly individuals, especially those with impaired balance or coordination.
• Impaired balance/coordination • Not recommended for patients with severe balance or coordination problems.
• Pregnancy and breastfeeding • Avoid using Zolpidem during pregnancy and while breastfeeding.

The side effects of Zolpidem Tartrate 6.25mg Tablet may include:

• Drowsiness
• Dizziness
• Headache
• Diarrhea
• Dry mouth
• Daytime sleepiness or grogginess
• Allergic reactions (rare)
• Unusual dreams or nightmares

Following are the precautions and warnings for Zolpidem Tartrate 6.25mg Tablet:

• This medication is intended for short-term use only, typically 7-10 days. Prolonged use without medical supervision can lead to dependence and tolerance.
• Zolpidem may impair your thinking and reactions, so avoid activities requiring mental alertness, such as driving or operating machinery, until you know how the medication affects you.
• Do not consume alcohol while taking Zolpidem, as it can increase the sedative effects and may lead to dangerous side effects.
• Inform your doctor if you have a history of liver or kidney disease, respiratory issues, or a history of substance abuse, as these conditions may require special precautions or adjustments in dosage.
• Elderly patients may be more sensitive to the effects of Zolpidem, so lower doses are often recommended for this age group.
• Zolpidem is not recommended for use in children, as its safety and efficacy have not been established in pediatric patients.
• If you have a history of depression, mental illness, or suicidal thoughts, inform your doctor, as Zolpidem may worsen these conditions.
• Always take Zolpidem exactly as prescribed by your healthcare provider, and do not increase the dosage or frequency without medical advice.

Following are the drug interactions for Zolpidem Tartrate 6.25mg Tablet:

• Alcohol and other CNS depressants (e.g., benzodiazepines, opioids) can increase the sedative effects and lead to respiratory depression.
• Rifampin, a strong CYP3A4 inducer, may decrease the effectiveness of Zolpidem by increasing its metabolism.
• Ketoconazole, a potent CYP3A4 inhibitor, can increase Zolpidem blood levels, leading to enhanced effects and potential toxicity.
• Avoid use with other sleep medications as it may result in excessive sedation and impaired psychomotor function.
• Medications that increase gastric pH (e.g., proton pump inhibitors) may decrease the absorption of Zolpidem.
• Zolpidem may interact with selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), increasing the risk of serotonin syndrome.
• Antifungal medications like itraconazole and voriconazole can increase plasma concentrations of Zolpidem, requiring dose adjustments.

Following are the food interactions for Zolpidem Tartrate 6.25mg Tablet:

• Avoid consuming alcohol with this medication as it can increase drowsiness and impair your ability to perform tasks requiring alertness.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Zolpidem, potentially leading to increased drug levels in the body.
• Fatty or heavy meals should be avoided before taking Zolpidem as they can slow down the absorption and effectiveness of the medication.
• Avoid caffeine-containing beverages like coffee, tea, or energy drinks, as they can counteract the sedative effects of Zolpidem and make it less effective.
• Dairy products, especially those high in fat, may slow down the absorption of Zolpidem, so it's best to take the medication on an empty stomach.
• Spicy foods may cause heartburn or acid reflux, which can interfere with the absorption of Zolpidem, so it's advisable to avoid spicy meals before taking the medication.
• Avoid large or heavy meals close to bedtime, as they can disrupt sleep and reduce the effectiveness of Zolpidem in promoting sleep.
• Always follow the dosage instructions provided by your healthcare professional, and do not take this medication with other sedatives or alcohol.

Zolpidem Tartrate 6.25mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to moisture or humidity. It is crucial to protect the medication from direct sunlight as it can degrade the active ingredients. Always check the expiration date, and never use the tablets beyond this date. For disposal, do not flush or pour the medication down the drain; instead, follow local guidelines for pharmaceutical waste disposal or consult a pharmacist for guidance on safe and environmentally friendly disposal practices. Keep this medication away from children and pets to prevent accidental consumption, which could be harmful.

Following are the quick tips for Zolpidem Tartrate 6.25mg Tablet:

• Take the tablet just before bedtime as directed by your doctor.
• Swallow the tablet whole with a glass of water, do not crush or chew.
• Zolpidem is a short-term treatment, so do not take it for extended periods without consulting your doctor.
• Avoid alcohol while taking this medication as it can increase drowsiness and impair coordination.
• Do not drive or operate machinery until you know how this medication affects you.
• Inform your doctor about all medications you are taking to avoid potential interactions.
• Store the tablets at room temperature, away from moisture and light.
• Dispose of any unused or expired medication properly, do not flush down the toilet.