STRESAM 50MG CAP (24S)

Etifoxine HCl 50MG, a unique anxiolytic medication, exerts its calming effects through a distinct mechanism of action. It primarily targets the gamma-aminobutyric acid (GABA) neurotransmitter system, but unlike traditional benzodiazepines, etifoxine selectively enhances the activity of specific GABA receptors, particularly the GABA-A receptor subtypes. This selective modulation increases the efficiency of GABAergic neurotransmission, promoting relaxation and reducing anxiety without the sedative and cognitive side effects often associated with benzodiazepines. Etifoxine's mechanism of action is believed to involve the facilitation of GABA-mediated chloride ion influx, leading to neuronal hyperpolarization and reduced neuronal excitability in the central nervous system, thereby alleviating anxiety symptoms effectively.

Etifoxine HCl 50MG

Benzodiazepine-like anxiolytic

Capsule

The following are the uses of Etifoxine HCl 50MG Capsule:

• Used for treating anxiety disorders, providing a calming effect without the sedative impact of traditional anxiolytics.
• Used for managing alcohol withdrawal symptoms, aiding in detoxification and reducing cravings.
• Used for addressing sleep disturbances associated with anxiety, promoting improved sleep quality.
• Used for supporting the management of generalized anxiety disorder, offering a well-tolerated therapeutic option.
• Used for providing symptomatic relief in cases of nervous tension and restlessness.
• Used for enhancing overall well-being by reducing anxiety-related physical symptoms.
• Used for facilitating a comprehensive approach to anxiety management, potentially in combination with therapy.

In the case of an overdose of Etifoxine HCl 50MG Capsule, the patient may experience symptoms such as dizziness, drowsiness, and in severe cases, respiratory depression. The severity of the overdose depends on the amount ingested and individual factors. It is important to seek medical assistance promptly and provide the healthcare provider with information about the medication, estimated dosage taken, and any observed symptoms. Timely intervention can help manage and mitigate the effects of an overdose.

In the case of a missed dose of Etifoxine HCl 50MG Capsule, it is generally recommended to take the missed dose as soon as you remember, provided it is not too close to the time for your next scheduled dose. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It's important to maintain a consistent medication routine, so try to set reminders or use a pill organizer to help you remember your daily doses.

To take Etifoxine HCl 50MG Capsule, swallow the capsule whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, ensuring not to exceed the prescribed daily amount.

Here are the conditions or situations when Etifoxine HCl 50MG Capsule should not be taken:

• Avoid if you have a known allergy or hypersensitivity to Etifoxine or any of its excipients.
• Not recommended for individuals with severe liver impairment or active liver disease.
• Contraindicated in patients with a history of acute angle-closure glaucoma.
• Should not be used in patients with myasthenia gravis.
• Avoid if you have a history of substance abuse or dependence.
• Not suitable for individuals with severe respiratory insufficiency.
• Do not use if you have a history of severe kidney disease.
• Contraindicated during breastfeeding, as it may pass into breast milk.

The side effects of Etifoxine HCl 50MG Capsule may include:

• Drowsiness or sedation
• Dry mouth
• Fatigue or weakness
• Dizziness
• Gastrointestinal disturbances (e.g., nausea, vomiting, diarrhea)
• Skin rashes or itching
• Sleep disturbances
• Muscle or joint pain

Following are the precautions and warnings for Etifoxine HCl 50MG Capsule:

• Not suitable for individuals with a known hypersensitivity or allergy to Etifoxine or any other ingredients in the capsule.
• Patients with a history of liver or kidney disease should exercise caution, as Etifoxine may require dosage adjustments in such cases.
• Etifoxine may cause drowsiness or dizziness; caution is advised when performing tasks that require alertness, such as driving or operating heavy machinery.
• Alcohol consumption should be avoided or limited as it may enhance the sedative effects of Etifoxine.
• This medication should be used with caution in the elderly, as they may be more sensitive to its effects.
• Pregnant and breastfeeding women should consult their doctor before taking Etifoxine, as the potential risks and benefits should be carefully considered.
• Keep out of reach of children and store in a cool, dry place.
• Do not exceed the prescribed dosage and duration of treatment without medical advice.

Following are the drug interactions for Etifoxine HCl 50MG Capsule:

• Avoid concurrent use with alcohol, as it may increase the sedative effects of Etifoxine.
• Etifoxine may enhance the effects of other central nervous system depressants like benzodiazepines, opioids, or antihistamines, leading to increased sedation and respiratory depression.
• The effectiveness of hormonal contraceptives may be reduced when taken with Etifoxine, so alternative contraceptive methods are recommended.
• It can interact with antiepileptic drugs, potentially reducing their efficacy and triggering seizures.
• Use with caution alongside anticoagulants, as Etifoxine may influence blood coagulation.
• Etifoxine may increase the sedative effects of antipsychotics and certain antidepressants.
• Drugs metabolized by CYP enzymes may have altered metabolism when taken with Etifoxine.

Following are the food interactions to be aware of when taking Etifoxine HCl 50MG Capsules:

• Alcohol consumption should be avoided as it may increase the sedative effects and impair your ability to drive or operate machinery.
• Grapefruit and grapefruit juice should be consumed with caution as they can interfere with the metabolism of the drug, potentially leading to increased side effects.
• High-fat meals may delay the absorption of Etifoxine, so it is best to take the medication on an empty stomach or as directed by your healthcare professional.
• Avoid caffeine or reduce intake as it can increase anxiety and counteract the calming effects of Etifoxine.
• Foods rich in tyramine, like aged cheeses, cured meats, and certain fermented foods, should be limited as they may interact with Etifoxine and increase blood pressure.
• Avoid excessive salt intake, as Etifoxine may interact with sodium levels in the body.
• Always ensure you are well-hydrated when taking this medication to support overall health.
• Consult your healthcare provider for personalized advice on dietary considerations while taking Etifoxine.

Etifoxine HCl 50MG Capsules should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area. Keep the capsules in their original packaging, ensuring the container is tightly sealed to maintain their integrity. Avoid exposure to direct sunlight, moisture, or extreme temperatures, as these conditions can degrade the medication. It is crucial not to store the capsules in the bathroom or kitchen, where humidity and heat can compromise their quality. Always check the expiration date, and if the capsules are past their expiry, do not consume them and dispose of them responsibly. Proper disposal methods include returning them to a pharmacy or following local guidelines for pharmaceutical waste disposal, ensuring they do not contaminate the environment. Keep the medication out of children's reach to prevent accidental ingestion.

Following are the quick tips for Etifoxine HCl 50MG Capsule:

• Take the capsule as directed by your doctor, usually once or twice daily.
• Swallow the capsule whole with a full glass of water, preferably at the same time each day.
• It can be taken with or without food, but taking it with food may help prevent stomach upset.
• Avoid crushing, chewing, or breaking the capsule; take it as a whole.
• Do not increase or decrease the dose without medical advice.
• Inform your doctor about all medications you are taking to avoid potential interactions.
• Store the capsules in a cool, dry place, away from direct sunlight and moisture.