Sulbamox (500mg) 6 Tablets

Amoxicillin/Sulbactam is a combination antibiotic that exhibits its bactericidal properties by inhibiting the synthesis of bacterial cell walls. Amoxicillin primarily works by binding to penicillin-binding proteins (PBPs), which are essential for forming the bacterial cell wall, leading to cell lysis. However, some bacteria produce beta-lactamase, an enzyme that can break down amoxicillin, rendering it ineffective. This is where Sulbactam comes into play. Sulbactam is a beta-lactamase inhibitor, meaning it protects amoxicillin from being degraded by beta-lactamase enzymes. By inhibiting beta-lactamase, Sulbactam enhances the effectiveness of Amoxicillin against a broader range of bacteria, including those that are resistant to amoxicillin alone. Together, Amoxicillin and Sulbactam act synergistically to combat bacterial infections by disrupting cell wall synthesis and preventing bacterial resistance.

Amoxicillin 500mg, Sulbactam 500mg

Antibiotic, beta-lactamase inhibitor.

Tablet

The following are the uses of Amoxicillin 500mg, Sulbactam 500mg Tablet:

• Used for treating bacterial infections such as respiratory tract infections, urinary tract infections, skin and soft tissue infections.
• Used to combat bacterial infections that are resistant to other antibiotics.
• Used for surgical prophylaxis to prevent infections during and after surgery.
• Used for the treatment of intra-abdominal infections, which can occur due to various gastrointestinal issues.
• Used to manage infections caused by bacteria that produce beta-lactamase enzymes, enhancing the effectiveness of amoxicillin.
• Used in severe cases of community-acquired pneumonia, providing a broad-spectrum of coverage.
• Used as an alternative for patients allergic to penicillin, offering a similar antibacterial effect.

In the case of an overdose of Amoxicillin 500mg and Sulbactam 500mg tablets, it is important to recognize the potential symptoms. These may include gastrointestinal issues such as nausea, vomiting, and diarrhea. Additionally, an overdose could lead to skin rashes, hypersensitivity reactions, and changes in blood parameters. Prompt medical intervention is necessary to manage these symptoms and prevent further complications.

In the case of a missed dose of Amoxicillin 500mg, Sulbactam 500mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for advice on how to safely adjust your medication regimen. It is crucial to maintain a consistent medication routine for the best therapeutic outcome.

To take Amoxicillin 500mg, Sulbactam 500mg tablets, swallow the tablet whole with a full glass of water, ensuring you complete the full course as prescribed by your healthcare provider, typically taken every 8 to 12 hours or as directed by your doctor.

Here are the conditions or situations when Amoxicillin 500mg, Sulbactam 500mg Tablet should not be used:

• Do not use if you are allergic to amoxicillin, sulbactam, penicillin, or any other beta-lactam antibiotics.
• Avoid if you have a history of severe allergic reactions to any antibiotics.
• Not suitable for patients with a history of cholestatic jaundice/hepatic dysfunction associated with amoxicillin/clavulanic acid.
• Do not use if you have mononucleosis or lymphatic leukemia.
• Contraindicated in patients with severe renal impairment (unless hemodialysis is performed).
• Do not administer if you have a history of gastrointestinal diseases, especially colitis.
• Should not be used if you have a history of severe diarrhea or antibiotic-associated diarrhea.

The side effects of Amoxicillin 500mg, Sulbactam 500mg Tablet may include:

• Diarrhea
• Nausea and vomiting
• Skin rash or itching
• Headache
• Dizziness
• Vaginal itching or discharge
• Joint pain
• Allergic reactions (such as hives, swelling, or difficulty breathing)

Following are the precautions and warnings for Amoxicillin 500mg, Sulbactam 500mg Tablet:

• This medication should not be used if you are allergic to any penicillin-type antibiotics or have a history of severe allergic reactions to similar drugs.
• Inform your doctor about any previous liver or kidney disease before taking this medication.
• Prolonged use may lead to the overgrowth of non-susceptible organisms, including fungi, which may require additional treatment.
• Elderly patients may be more susceptible to side effects, especially related to the kidneys and nervous system.
• Caution is advised in patients with a history of gastrointestinal diseases, as it may cause gastrointestinal upset.
• This medication should be used with caution in patients with a history of seizures or epilepsy, as it may lower the seizure threshold.
• Pregnant and breastfeeding women should consult their doctor before taking this medication, as it may have potential risks to the fetus or infant.

Following are the drug interactions for Amoxicillin 500mg, Sulbactam 500mg Tablet:

• Probenecid slows down the removal of amoxicillin from the body, leading to higher and more prolonged blood levels.
• Concomitant use with Methotrexate may increase methotrexate levels, potentially increasing the risk of methotrexate toxicity.
• Allopurinol may increase the risk of skin rash with amoxicillin.
• Anticoagulants like warfarin may have their effect enhanced, requiring monitoring of coagulation parameters.
• Nephrotoxic drugs (e.g., certain antibiotics or diuretics) may increase the risk of kidney problems when used with this medication.
• Oral contraceptives may be less effective when taken with amoxicillin.
• The efficacy of Amoxicillin may be reduced when taken with Chloramphenicol.

Following are the food interactions for Amoxicillin 500mg, Sulbactam 500mg Tablet:

• Avoid consuming alcohol during the medication course as it may reduce the effectiveness of Amoxicillin and increase the risk of side effects.
• Grapefruit and grapefruit juice should be consumed with caution as they may alter the absorption of Amoxicillin, potentially affecting its effectiveness.
• Dairy products like milk, cheese, and yogurt should be consumed separately from the medication, as calcium can bind with Amoxicillin, reducing its absorption.
• Avoid high-fat meals as they may delay the absorption of the medication, leading to reduced effectiveness.
• Ensure adequate fluid intake to maintain hydration, especially if experiencing diarrhea as a side effect.
• Foods rich in vitamin K, such as leafy greens, should be consumed consistently to maintain normal blood clotting, as the medication may interfere with vitamin K absorption.
• Probiotics can be beneficial after completing the antibiotic course to restore healthy gut bacteria.
• No significant interactions with specific foods are known, but always consult your healthcare provider for personalized advice.

Amoxicillin 500mg, Sulbactam 500mg Tablets should be stored in a cool and dry place, preferably at room temperature (68°F to 77°F). It is crucial to keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to moisture and light. Avoid storing them in the bathroom or kitchen, as these areas can be susceptible to temperature fluctuations and humidity. Proper disposal of unused or expired medication is essential; do not flush the tablets or throw them into the garbage. Contact your pharmacist or healthcare provider for guidance on safe disposal methods. Keep the medication out of the sight and reach of children to prevent accidental consumption.

Following are the quick tips for Amoxicillin 500mg, Sulbactam 500mg Tablet:

• Take the tablet as directed by your doctor, usually every 8 or 12 hours.
• Ensure you complete the full course as prescribed, even if you feel better.
• Swallow the tablet whole with a full glass of water, preferably at the start of a meal.
• Maintain a consistent dosing schedule to ensure the medication's effectiveness.
• Store the tablets at room temperature, away from moisture and light.
• Do not crush or chew the tablet; it is designed for extended release.
• Inform your doctor if you have any allergies or medical conditions before starting this medication.