Sumoxen (85/500mg) 2 Tablets

The combination tablet of Naproxen 500 mg and Sumatriptan 85 mg is used for the acute treatment of migraines. Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain by inhibiting cyclooxygenase (COX) enzymes, which are involved in the production of prostaglandins. Sumatriptan is a selective serotonin receptor agonist (5-HT1 receptor), which works by constricting dilated blood vessels in the brain and inhibiting the release of pain-inducing substances. Together, this combination provides rapid relief from migraine symptoms, including headache, nausea, and sensitivity to light or sound.

NSAID and Triptan.

Tablet

The following are the uses of Naproxen 500mg, Sumatriptan 85mg Tablet:

• Used for relieving acute pain, inflammation, and fever.
• Used for the short-term management of acute migraine attacks.
• Used for reducing swelling and stiffness in conditions like arthritis.
• Used to treat headaches, muscle aches, and menstrual cramps.
• Used for its analgesic and anti-inflammatory properties.
• Used to provide relief from symptoms associated with tension headaches.
• Used to target specific neurotransmitters to constrict blood vessels and reduce migraine symptoms.

In the case of an overdose of Naproxen 500mg and Sumatriptan 85mg tablets, symptoms may include severe drowsiness, nausea, vomiting, abdominal pain, and in extreme cases, seizures or loss of consciousness. It is crucial to seek medical advice promptly, as the severity of symptoms can vary based on individual factors. Timely intervention can help manage the effects of an overdose and prevent potential complications. Prompt action ensures the best possible outcome in such situations.

In the case of a missed dose of Naproxen 500mg, take the missed dose as soon as you remember, but if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose to make up for a missed one. For Sumatriptan 85mg Tablet, if you miss a dose and you still have a headache, take the missed dose as soon as possible. If you don't have a headache, it is best to skip the missed dose and wait for the next scheduled dose.

To take Naproxen 500mg and Sumatriptan 85mg Tablet, swallow the tablet whole with a full glass of water, preferably with or after a meal, as directed by your healthcare professional; do not crush, chew, or break the tablet, and ensure you adhere to the prescribed dosage and treatment duration.

Here are the conditions or situations when Naproxen 500mg and Sumatriptan 85mg Tablet should not be used:

• Should not be used in individuals with a known allergy to Naproxen, Sumatriptan, or any non-steroidal anti-inflammatory drugs (NSAIDs).
• Contraindicated in patients with a history of heart attack, stroke, or blood clotting disorders.
• Not suitable for individuals with severe liver or kidney impairment.
• Should be avoided in patients with uncontrolled high blood pressure.
• Do not use if there is a history of stomach or intestinal bleeding or perforation.
• Contraindicated during the last trimester of pregnancy.
• Not recommended for individuals with severe or uncontrolled asthma.
• Should not be used in patients with a history of a severe allergic reaction to other medications.
• Avoid using if there is a history of brain-related bleeding or stroke.

The side effects of Naproxen 500mg may include:

• Stomach pain or upset
• Nausea or vomiting
• Dizziness or headache
• Drowsiness or fatigue
• Heartburn or indigestion
• Diarrhea
• Increased blood pressure
• Chest tightness or discomfort
• Weakness or numbness in limbs
• Nausea and vomiting
• Dizziness or vertigo
• Sensitivity to light and sound
• Neck stiffness
• Tingling sensations

Following are the precautions and warnings for Naproxen 500mg and Sumatriptan 85mg Tablet:

• Do not take this medication if you have a known allergy to Naproxen or Sumatriptan or any other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
• Patients with a history of gastrointestinal bleeding, heart disease, high blood pressure, or liver problems should use this medication with caution and under medical supervision.
• This medication may increase the risk of serious cardiovascular events, including heart attack and stroke, especially with long-term use. Monitor for any chest pain or cardiovascular symptoms.
• Naproxen can cause stomach irritation; it is advised to take it with food or milk to minimize this effect.
• Avoid alcohol consumption while taking this medication as it may increase the risk of gastrointestinal bleeding.
• Do not take this medication during pregnancy or breastfeeding unless directed by a healthcare professional.
• Discontinue use and seek medical attention if you experience severe skin reactions, persistent stomach pain, or signs of an allergic reaction.

Following are the drug interactions for Naproxen 500mg and Sumatriptan 85mg Tablet:

• Using Naproxen with other non-steroidal anti-inflammatory drugs (NSAIDs) or aspirin may increase the risk of gastrointestinal bleeding and ulcers.
• Sumatriptan may interact with other triptans, ergotamine, or other serotonin-affecting drugs, increasing the risk of serotonin syndrome.
• Naproxen can decrease the effectiveness of angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) used for blood pressure control.
• It may increase the risk of bleeding when taken with anticoagulants like warfarin or heparin.
• Naproxen can reduce the elimination of lithium, leading to potential lithium toxicity.
• The effectiveness of Sumatriptan may be reduced by selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs).
• Use with monoamine oxidase inhibitors (MAOIs) is contraindicated due to the risk of hypertensive crisis.

Following are the food interactions for Naproxen 500mg and Sumatriptan 85mg Tablet:

• Alcohol consumption should be avoided or limited as it can increase the risk of gastrointestinal bleeding and liver-related issues when combined with Naproxen.
• Naproxen should be taken with food to reduce stomach irritation and potential ulcers.
• Avoid grapefruit and grapefruit juice as they may affect the metabolism of Naproxen, increasing its levels in the body.
• For Sumatriptan, avoid consuming large amounts of caffeine-containing foods and beverages (like coffee, tea, or chocolate) as it may increase the risk of side effects such as increased heart rate and blood pressure.
• Foods high in tyramine (aged cheeses, cured meats, fermented foods) should be avoided when taking Sumatriptan to reduce the risk of potential blood pressure elevation.
• Avoid consuming alcohol with Sumatriptan as it may lead to increased drowsiness and impaired concentration.
• Taking Sumatriptan with food can slow down its absorption, so it is best taken on an empty stomach for faster relief.

Naproxen 500mg and Sumatriptan 85mg tablets should be stored in a secure and dry location, preferably in their original packaging, at room temperature, away from excessive heat, moisture, and direct sunlight. It is crucial to keep the medication in a safe place, out of the reach of children and pets. When disposing of unused or expired tablets, do not throw them into the trash or flush them down the toilet. Instead, follow local guidelines for medication disposal or consult your pharmacist for environmentally friendly disposal options, ensuring that the medication is disposed of responsibly and safely. Proper storage and disposal practices help maintain the integrity of the medication and contribute to environmental protection.

Following are the quick tips for Naproxen 500mg and Sumatriptan 85mg Tablet:

• Consult your doctor before taking these medications, especially if you have a medical history or are taking other drugs.
• Take Naproxen with food or milk to prevent stomach upset.
• Ensure you drink plenty of fluids when taking Naproxen to reduce the risk of kidney problems.
• Do not crush or chew Sumatriptan tablet; swallow it whole with water.
• Take Sumatriptan as soon as possible at the onset of a migraine headache as directed by your doctor.
• Avoid driving or operating machinery until you know how these medications affect you.
• Store both medications at room temperature, away from moisture and light.