Symbidow (400/12mcg) 30 Capsules

The mechanism of action of Budesonide 400mcg and Formoterol 12mcg in combination therapy is as follows,Budesonide is a potent corticosteroid that exhibits anti-inflammatory properties by binding to glucocorticoid receptors in airway cells, reducing inflammation and mucus production in the airways. It helps to decrease swelling and irritation in the lungs. On the other hand, Formoterol is a long-acting beta-2 agonist (LABA) that stimulates beta-2 receptors in the airways, leading to smooth muscle relaxation and bronchodilation. This action helps to open up constricted airways, making it easier to breathe. The combination of these two medications provides both an anti-inflammatory effect from Budesonide and a bronchodilator effect from Formoterol, working together to improve lung function and control symptoms in respiratory conditions such as asthma or chronic obstructive pulmonary disease (COPD).

Budesonide 400mcg, Formoterol 12mcg

Corticosteroid/Long-acting beta-agonist.

Capsule

The following are the uses of Budesonide 400mcg, Formoterol 12mcg Capsule:

• Used for preventing asthma attacks and managing chronic obstructive pulmonary disease (COPD).
• Used for reducing inflammation in the lungs.
• Used to quickly relax and open airways during sudden asthma symptoms or before exercise.
• Used for long-term control and management of asthma symptoms.
• Used to improve breathing and reduce wheezing.
• Used for reducing the frequency and severity of asthma flare-ups.
• Used to enhance overall lung function and quality of life for asthma patients.

To be taken as per doctor's prescription

In the case of an overdose of Budesonide 400mcg and Formoterol 12mcg capsules, the patient may experience symptoms such as rapid heart rate, tremors, headache, and muscle weakness. It is important to seek medical advice immediately if an overdose is suspected. The healthcare provider may recommend appropriate measures, including monitoring vital signs and providing supportive care to manage the symptoms effectively. Prompt action can help prevent potential complications.

In the case of a missed dose of Budesonide 400mcg and Formoterol 12mcg Capsule, it is generally recommended to take the missed dose as soon as you remember, provided there is a sufficient gap before the next scheduled dose. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. It's important to try to take your medication as prescribed, but if you frequently miss doses, inform your healthcare provider for further guidance.

To use Budesonide 400mcg and Formoterol 12mcg Capsule, twist open the capsule and inhale the contents using the provided inhaler device, ensuring a deep inhalation to maximize the medication's effectiveness; follow the prescribed dosage as directed by your healthcare provider.

Following are the conditions or situations when Budesonide 400mcg and Formoterol 12mcg Capsule should not be used:

• Should not be used in individuals with a known allergy to Budesonide, Formoterol, or any of the excipients in the capsule.
• Not indicated for the treatment of acute asthma attacks or acute bronchospasm.
• Contraindicated in patients with severe hypersensitivity reactions to other drugs or food preservatives.
• Should not be used in patients with a history of paradoxical bronchospasm with Formoterol or other similar medications.
• Not recommended for individuals with severe, uncontrolled asthma or COPD.
• Should be avoided in patients with severe heart problems or cardiovascular disease.
• Not suitable for individuals with uncontrolled high blood pressure.
• Should not be used in patients with a history of seizures or convulsions.
• Contraindicated during acute asthma episodes, as it is a long-term maintenance medication.

The side effects of Budesonide 400mcg, Formoterol 12mcg Capsule may include:

• Headache
• Throat irritation or pain
• Hoarseness or changes in voice
• Tremor or shaking
• Palpitations or increased heart rate
• Muscle cramps or spasms
• Upset stomach or nausea
• Weakness or fatigue

Following are the precautions and warnings for Budesonide 400mcg, Formoterol 12mcg Capsule:

• Not suitable for individuals with a known allergy to Budesonide, Formoterol or any other ingredients in the capsule.
• Patients with a history of heart problems, high blood pressure, diabetes, seizures, or thyroid issues should use with caution and under medical supervision.
• Avoid sudden discontinuation of the medication; dosage adjustments should be gradual.
• May cause increased heart rate and tremors, consult a doctor if these symptoms occur.
• Not recommended for children without medical advice.
• Elderly patients may be more sensitive to the effects and should be closely monitored.
• Inform your doctor about all medications you are taking to avoid potential drug interactions.
• Consult a healthcare professional if you have any respiratory infections or conditions before starting this medication.

Following are the drug interactions for Budesonide 400mcg, Formoterol 12mcg Capsule:

• Ketoconazole, itraconazole, and other strong CYP3A4 inhibitors can increase the exposure of budesonide, potentially leading to increased risk of systemic corticosteroid effects.
• Macrolide antibiotics (e.g., clarithromycin, erythromycin) may inhibit CYP3A4, increasing formoterol levels and the risk of adverse effects.
• Beta-blockers (e.g., propranolol, atenolol) may counteract the effects of formoterol, as they block beta-adrenergic receptors.
• Theophylline and aminophylline may increase the risk of adverse effects when combined with formoterol, as they have additive effects on the respiratory system.
• Concomitant use with other long-acting beta2-agonists (LABAs) or other sympathomimetic drugs may increase the risk of cardiovascular effects.
• Non-potassium sparing diuretics (e.g., loop diuretics, thiazide diuretics) may cause hypokalemia, which can increase the risk of adverse cardiac events when combined with formoterol.
• MAO inhibitors can interact with formoterol, potentially causing a hypertensive crisis.

Following are the food interactions for Budesonide 400mcg, Formoterol 12mcg Capsule:

• Avoid consuming grapefruit or grapefruit juice as it may interfere with the medication's metabolism, leading to increased drug levels in the body.
• Alcohol intake should be limited as it may enhance the sedative effects of Formoterol, causing dizziness or drowsiness.
• Caffeine-rich foods and beverages like coffee, tea, and energy drinks should be consumed in moderation to prevent potential heart rhythm disturbances.
• High-fat meals can delay the absorption of Budesonide, potentially affecting its efficacy.
• Avoid potassium-rich foods like bananas, oranges, and leafy greens if taking potassium-sparing diuretics alongside this medication.
• Maintain a balanced diet, ensuring adequate fluid intake to support respiratory health and overall well-being.
• Avoid excessive salt intake as it may counteract the effects of Budesonide in managing respiratory conditions.
• Consult your healthcare provider for personalized dietary recommendations based on your medical history and medication regimen.

Budesonide 400mcg, Formoterol 12mcg capsules should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. Keep the capsules in their original packaging, tightly sealed, to maintain their integrity. It is crucial not to store them in the bathroom or near heat sources, as temperature fluctuations can impact their effectiveness. Always check the expiration date, and if the medication is expired or no longer needed, do not flush or pour it down the drain. Consult your pharmacist for safe disposal methods to protect the environment. Keep the medication securely stored away from children to prevent accidental consumption.

No

Following are the quick tips for Budesonide 400mcg, Formoterol 12mcg Capsule:

• Take the capsule as directed by your doctor, typically once or twice daily.
• Swallow the capsule whole with a glass of water; do not crush, chew, or break it.
• Ensure you inhale the medication deeply and slowly for maximum effectiveness.
• Maintain a consistent dosing schedule for best results.
• Do not stop taking the medication without consulting your doctor, even if you feel better.
• Store the capsules in a cool, dry place, away from direct sunlight and moisture.
• Keep a record of your symptoms and lung function to track the medication's effectiveness.