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Phenylephrine injection acts primarily by stimulating alpha-adrenergic receptors, which are located in the blood vessels. This stimulation causes vasoconstriction, leading to a narrowing of the blood vessels. The mechanism involves the activation of alpha-1 adrenoceptors, primarily in the arterioles and veins, resulting in an increase in peripheral vascular resistance. This action reduces blood flow through the dilated vessels, particularly in the nasal passages, which leads to a decrease in congestion and inflammation. The constriction of blood vessels helps to reduce nasal congestion by shrinking swollen nasal tissues, allowing for easier breathing. By promoting vasoconstriction, phenylephrine effectively reduces nasal congestion and provides symptomatic relief without directly affecting the histamine response.
Alpha-adrenergic agonist
Injection
The following are the uses of Phenylephrine Injection:
In the case of an overdose of Phenylephrine Injection, individuals may experience severe hypertension, resulting in a rapid and forceful heartbeat. Other symptoms include nervousness, headaches, and nausea. Immediate medical intervention is necessary, as treatment should focus on managing these symptoms and stabilizing blood pressure. This may involve administering medications to counteract the effects of phenylephrine and closely monitoring vital signs until the patient's condition improves.
In the case of a missed dose of Phenylephrine Injection, it is important to administer the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose, it is best to skip the missed dose to avoid a potential overdose. Never double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare professional for advice on how to safely resume the medication. It is crucial to follow the prescribed dosing schedule to ensure the medication's effectiveness and to minimize potential side effects.
To administer Phenylephrine Injection, clean the injection site with an alcohol swab, insert the needle at a 90-degree angle, and slowly inject the prescribed dose subcutaneously, ensuring the entire medication is delivered, and then gently apply pressure with a cotton ball or gauze to stop any minor bleeding.
Following are the conditions/situations when Phenylephrine Injection should not be administered:
The possible side effects of Phenylephrine Injection may include:
Following are the precautions and warnings for Phenylephrine Injection:
Following are the drug interactions for Phenylephrine Injection:
Following are the food interactions for Phenylephrine Injection:
Phenylephrine Injection should be stored in a controlled room temperature environment, typically between 20-25°C (68-77°F), in its original packaging to protect it from light and moisture. Ensure the injection is kept away from direct sunlight and extreme temperatures, as it can affect the medication's potency. It is crucial to check the expiration date regularly and dispose of any expired or unused injections promptly. When disposing of Phenylephrine Injection, do not throw it into the trash or flush it down the toilet; instead, follow local guidelines for pharmaceutical waste disposal or consult a healthcare professional for guidance on safe disposal methods. Keep the medication out of children's reach to prevent accidental exposure.
Following are the quick tips for Phenylephrine Injection:
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