SYNFLORIX 0.5ML VACCINE

Salicylic Acid and Ciclopirox Olamine work synergistically to combat various skin conditions. Salicylic Acid is a keratolytic agent that aids in shedding the outer layer of skin. It achieves this by breaking down the connections between cells in the epidermis, promoting exfoliation and unclogging pores. This action helps to remove dead skin cells and reduce scaling, making it particularly effective for treating psoriasis, seborrheic dermatitis, and other skin disorders. Ciclopirox Olamine, on the other hand, is a synthetic antifungal agent that inhibits the growth of fungi by disrupting their cellular membranes and metabolic processes. It specifically targets the fungal enzymes involved in ergosterol synthesis, a critical component of fungal cell membranes, thereby weakening the membrane structure and function. This dual mechanism of action helps to alleviate symptoms associated with fungal infections and improve overall skin health.

Antifungal, Keratolytic.

Injection

The following are the uses of Salicylic Acid, Ciclopirox Olamine Injection:

• Used for treating acne and reducing breakouts by unclogging pores
• Used for exfoliating the skin, removing dead skin cells, and improving skin texture
• Used for reducing skin redness and inflammation in various skin conditions
• Used for treating psoriasis and relieving itching, scaling, and redness
• Used for clearing dandruff and improving scalp health
• Used for softening and removing corns, calluses, and warts
• Used for reducing and preventing the recurrence of skin rashes and irritations

In the case of an overdose of Salicylic Acid or Ciclopirox Olamine Injection, individuals may experience symptoms such as gastrointestinal disturbances, including nausea, vomiting, and stomach pain. Additionally, excessive use can lead to skin irritation, redness, and peeling. In severe cases, overdoses may result in dizziness, headache, and even respiratory distress. It is important to seek medical advice promptly if an overdose is suspected to ensure appropriate treatment and management.

In the case of a missed dose of Salicylic Acid, it is generally advised to apply the medication as soon as you remember. However, if it's almost time for your next application, skip the missed dose and continue with your regular schedule. For Ciclopirox Olamine Injection, if you forget to administer a dose, administer it as soon as you remember. If it's almost time for your next dose, you may skip the missed dose and continue with your regular dosing schedule. It's important to maintain consistency with these medications for optimal results.

To administer Salicylic Acid and Ciclopirox Olamine Injection, clean the affected area, open the ampoule, and apply the solution directly to the skin using a sterile applicator, following the prescribed dosage and frequency as directed by your healthcare provider.

Following are the conditions/situations to avoid the use of Salicylic Acid:

• Do not use on broken or infected skin.
• Avoid contact with eyes, nose, mouth, and other mucous membranes.
• Not recommended for individuals with an allergy to aspirin or salicylates.
• Do not use on children under 2 years of age without medical advice.
• Avoid using on large areas of the body or for prolonged periods without consulting a doctor.
• Do not use if you are allergic to ciclopirox or any of the ingredients in the injection.
• Avoid using if you have severe kidney or liver disease.
• Not recommended for individuals with a history of hypersensitivity reactions to similar antifungal medications.
• Do not use if you are pregnant or breastfeeding without medical advice.
• Avoid using on infected or severely damaged skin.

The side effects of Salicylic Acid and Ciclopirox Olamine Injection may include:

• Skin irritation or redness at the application site
• Itching or burning sensation
• Dry skin
• Peeling or scaling of the skin
• Mild stinging or tingling
• Allergic reactions (such as rash, hives, or difficulty breathing)
• In rare cases, changes in skin color or hyperpigmentation.
• Nail changes or discoloration

Following are the precautions and warnings for Salicylic Acid, Ciclopirox Olamine Injection:

• Avoid using this medication if you are allergic to salicylic acid, ciclopirox olamine, or any other related compounds.
• Do not use this medication on open wounds, infected areas, or broken skin.
• Keep it away from eyes, nose, mouth, and other mucous membranes. In case of contact, rinse thoroughly with water.
• This medication may cause skin irritation or dryness; discontinue use if severe irritation occurs.
• Not recommended for children without medical supervision.
• Consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Do not use this medication for longer than prescribed, and follow the instructions provided by your healthcare professional.

Following are the drug interactions for Salicylic Acid and Ciclopirox Olamine Injection:

• Salicylic Acid may interact with anticoagulants, increasing the risk of bleeding. It can prolong bleeding time and enhance the effects of anticoagulants.
• Ciclopirox has shown to interact with drugs that are metabolized by the liver's cytochrome P450 enzymes, potentially altering their metabolism.
• Salicylic Acid can increase the risk of toxicity when used with other topical agents containing resorcinol, sulfur, or phenol.
• It may also interact with medications affecting renal function, as it is primarily eliminated through the kidneys.
• Ciclopirox Olamine should be used cautiously with drugs that may cause renal impairment, as it is primarily excreted via the kidneys.
• Salicylic Acid can compete with other acidic drugs for renal tubular secretion, potentially affecting the excretion of these drugs.
• Avoid using other topical medications without consulting a healthcare professional, as combining treatments may increase skin irritation.

Following are the food interactions for this Injection:

• Avoid excessive consumption of foods rich in salicylates (such as almonds, apples, berries, cucumbers, and tomatoes) while using Salicylic Acid, as it may lead to increased blood levels of salicylates and potential toxicity.
• Salicylic Acid may decrease the absorption of folic acid (a B-vitamin) from food sources like leafy greens and legumes, so ensure you're getting enough of this nutrient in your diet.
• Spicy foods can sometimes irritate skin treated with Salicylic Acid, so consider reducing spicy food intake during treatment.
• Ciclopirox Olamine may cause gastrointestinal upset, so consuming a diet rich in soothing foods like oatmeal, yogurt, and ginger can help alleviate these symptoms.
• Ensure adequate hydration by drinking plenty of water to support the overall health of your skin and body during treatment.
• There are no specific food restrictions with Ciclopirox Olamine, but maintaining a balanced diet is always recommended for overall well-being.

Salicylic Acid, Ciclopirox Olamine Injection should be stored in a controlled environment, preferably in a cool and dry place, away from direct sunlight and moisture. The ideal storage temperature is between 68°F and 77°F (20°C and 25°C). It is crucial to keep the medication in its original packaging, tightly sealed, to maintain its integrity and prevent contamination. When disposing of unused or expired injections, do not dispose of them via household waste or wastewater systems. Instead, contact your healthcare professional or pharmacist for guidance on proper disposal methods, ensuring compliance with local regulations and guidelines. Keep this medication securely stored and out of the reach of children and pets to prevent accidental exposure.

Following are the quick tips for Salicylic Acid and Ciclopirox Olamine:

• Wash the affected area and ensure it is clean and dry before applying the medication.
• Apply a thin layer as directed, covering the affected area completely.
• Use the medication regularly for the prescribed duration, even if symptoms improve.
• Do not cover the treated area with bandages or tight clothing to allow ventilation.
• Avoid using other topical products on the treated area without medical advice.
• Inform your doctor if symptoms persist or worsen after several days of use.
• Store the medication at room temperature, away from moisture and direct sunlight.