Tacrol (0.03%) 5g Ointment

Tacrol (0.03%) 5g Ointment

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  • Manufacturer MISC
  • Generic Name Terbinafine

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Terbinafine ointment, a topical antifungal medication, exhibits its antifungal activity through a specific mechanism of action. It primarily targets the enzyme squalene epoxidase within the fungal cell, which is crucial for the biosynthesis of ergosterol, a key component of the fungal cell membrane. By inhibiting squalene epoxidase, terbinafine disrupts the synthesis of ergosterol, leading to the accumulation of squalene and a deficiency of ergosterol in the fungal cell. This alteration in the cell membrane composition compromises its integrity and functionality, ultimately inhibiting fungal growth and proliferation. The selective inhibition of squalene epoxidase makes terbinafine highly effective against a range of dermatophytes and certain other fungi, contributing to its therapeutic efficacy in treating various superficial fungal infections.

  • Ingredients

    Terbinafine
  • Drug Class

    Antifungal

  • Dosage Form

    Ointment

  • Uses

    The following are the uses of Terbinafine Ointment:

    • Used for treating fungal infections such as athlete's foot, jock itch, and ringworm.
    • Used for relieving itching, redness, and burning caused by these infections.
    • Used for preventing the infection from spreading to other areas.
    • Used for improving skin appearance and reducing scaling and cracking.
    • Used for eliminating the fungus causing the infection.
    • Used for maintaining skin health and preventing recurrence.
    • Used for providing targeted relief directly to the affected area.
  • In case of Overdose

    In the case of an overdose of Terbinafine Ointment, it is important to recognize the potential risks. While rare, excessive use may lead to an increase in adverse effects, such as skin irritation or liver problems. If you suspect an overdose, promptly contact a healthcare professional or a poison control center for guidance. They will provide specific instructions based on the amount and circumstances of the overdose, ensuring the best course of action for your well-being.

  • Missed Dose

    In the case of a missed dose of Terbinafine Ointment, it is important to apply the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply extra ointment to make up for the missed dose, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or alarms to help you stay on track with your treatment plan. Consult your healthcare provider if you have any concerns or questions about managing missed doses of this medication.

  • How To Use

    To apply Terbinafine Ointment, clean and dry the affected skin area, then apply a thin layer of the ointment, gently rubbing it into the skin once or twice a day, or as directed by your healthcare professional, ensuring you cover the entire affected area.

  • When Not to Use

    Following are the conditions/situations to avoid when using Terbinafine Ointment:

    • Do not use if you are allergic to any of its ingredients, including terbinafine or similar antifungal medications.
    • Avoid using on open wounds, burns, or severely broken skin.
    • Not recommended for individuals with a history of liver or kidney disease.
    • Should not be used on skin conditions like eczema, psoriasis, or severe skin inflammation.
    • Avoid using on areas of skin affected by other skin disorders without medical advice.
    • Not suitable for children without medical supervision and prescription.
    • Do not use if you are pregnant or breastfeeding without consulting a doctor.
    • Do not use beyond the prescribed duration or on larger skin areas than advised.
  • Side Effects

    The side effects of Terbinafine Ointment may include:

    • Skin irritation or burning at the application site
    • Itching or redness
    • Dry skin
    • Peeling or flaking skin
    • Rash or hives
    • Swelling or inflammation
    • Blisters or sores
    • Changes in skin color
  • Precautions & Warnings

    Following are the precautions and warnings:

    • Terbinafine Ointment should be used with caution in individuals with known allergies to any of its ingredients, and should be avoided if a person is allergic to terbinafine or similar antifungal medications.
    • Not recommended for individuals with severe liver or kidney disease, as it may require dosage adjustments or close monitoring.
    • Avoid applying the ointment to broken or severely damaged skin, and do not use it on the face or eyes.
    • If irritation, redness, or swelling occurs at the application site, discontinue use and consult a healthcare professional.
    • Do not use the ointment for longer than the recommended period; follow the prescribed duration of treatment.
    • Terbinafine Ointment is for external use only; do not ingest or apply to mucous membranes.
    • Keep out of reach of children and pets; accidental ingestion may cause serious side effects.
  • Drug Interactions

    Following are the drug interactions for Terbinafine Ointment:

    • No significant drug interactions have been reported with Terbinafine Ointment when used topically.
    • Terbinafine may interact with oral antifungal medications, such as itraconazole or fluconazole, potentially increasing the risk of liver-related side effects.
    • Avoid using other topical antifungal medications simultaneously to prevent additive effects and potential skin irritation.
    • Alcohol-based products or those containing harsh chemicals may cause increased skin dryness or irritation when used with Terbinafine Ointment.
    • Inform your doctor if you are taking any oral medications, as Terbinafine can interact with certain drugs metabolized by the liver.
    • The effectiveness of hormonal contraceptives may be reduced when using Terbinafine systemically; consider alternative contraceptive methods.
    • Topical corticosteroids should be used cautiously with Terbinafine Ointment, as they may mask the symptoms of a fungal infection.
  • Food Interactions

    Following are the food interactions for Terbinafine Ointment:

    • Terbinafine may interact with certain foods, although the significance of these interactions is generally low.
    • Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of the drug, leading to increased levels of Terbinafine in the body.
    • Alcohol consumption is not known to directly interact with Terbinafine Ointment, but it's advisable to avoid excessive alcohol use during treatment.
    • Avoid consuming high-fat meals while using the ointment as it may impact the absorption of the medication through the skin.
    • Some dairy products and calcium-rich foods may slightly reduce the absorption of Terbinafine, but this effect is usually minimal.
    • Caffeine intake should be monitored as it may affect the skin's sensitivity, especially if you experience side effects like itching or redness.
    • There is no known interaction with spicy foods, but it's best to avoid applying the ointment immediately after consuming spicy meals to minimize skin irritation.
    • Always consult your healthcare provider for personalized advice regarding diet and medication interactions.
  • Storage/Disposal

    Terbinafine Ointment should be stored in a cool and dry place, preferably at room temperature, ensuring it is kept away from direct sunlight, heat, and moisture. It is crucial to retain the medication in its original packaging, securely sealed, to maintain its integrity and prevent contamination. Remember to check the expiration date regularly, and when it's time to discard the ointment, do not flush or pour it down the drain. Instead, seek advice from your pharmacist or healthcare professional on the appropriate disposal methods for this medication. Additionally, always keep medicines out of children's reach to prevent accidental ingestion.

  • Quick Tips, if any

    Following are the quick tips for Terbinafine Ointment:

    • Wash and dry the affected area before applying the ointment.
    • Apply a thin layer to the affected skin, gently rubbing it in until absorbed.
    • Use the ointment as directed, typically once or twice daily, for the full prescribed duration.
    • Wash your hands after application to avoid accidental contact with eyes or mouth.
    • Avoid applying the ointment to broken or irritated skin.
    • Do not cover the treated area with bandages or tight clothing.
    • Store the ointment at room temperature, away from direct sunlight and moisture.

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