Tansomec 550/5ml inj 10s

Tranexamic acid injection works by inhibiting the activation of plasminogen to plasmin, which is a key enzyme in the breakdown of blood clots. It competitively blocks the binding sites of plasminogen on the fibrin clot, thereby preventing its conversion to plasmin. By inhibiting plasmin formation, tranexamic acid helps to stabilize existing clots and promotes hemostasis. This mechanism reduces fibrinolysis and the dissolution of clots, leading to reduced bleeding and improved clot stability, particularly in situations where excessive bleeding or fibrinolysis is a concern.

Antifibrinolytic.

injection

The following are the uses of Tranexamic Acid injection:

• Used for controlling heavy bleeding during surgery, especially in cardiac, orthopedic, and gynecological procedures.
• Used for treating life-threatening bleeding after trauma or childbirth.
• Used for managing bleeding disorders such as hemophilia and von Willebrand disease.
• Used for reducing blood loss and the need for blood transfusions in various surgical settings.
• Used for preventing excessive bleeding in patients with liver disease or before certain dental procedures.
• Used for controlling bleeding in patients with inherited or acquired bleeding disorders.
• Used for treating menorrhagia (heavy menstrual bleeding) when other treatments are ineffective.
• Used for reducing bleeding risk in patients undergoing major surgeries, ensuring better surgical outcomes.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For heavy menstrual bleeding (menorrhagia)- Take 1 tablet of Tranexamic Acid 250mg 3 times a day, ideally at mealtimes to reduce stomach upset.
• For thrombocytopenia (low platelet count)- The dose will depend on the severity of your condition and your doctor's assessment. The typical starting dose is 1g (1,000mg) daily, divided into 3 smaller doses of 333mg taken at mealtimes. Your doctor may adjust this dose depending on your response and tolerance.
• For dental surgery- The recommended dose is 1 tablet of Tranexamic Acid 250mg taken 2 hours before surgery, followed by another tablet after an hour, and then a third tablet 2 hours after the surgery. This regimen helps reduce the risk of bleeding during and after the procedure.

In the case of an overdose of Tranexamic Acid injection, prompt medical intervention is necessary. Symptoms may include nausea, vomiting, diarrhea, and in severe cases, seizures or loss of consciousness. It is crucial to seek emergency medical care, where treatment will focus on managing symptoms and ensuring the patient's vital functions are stable. The healthcare provider may administer specific antidotes or treatments to counteract the effects of the overdose.

In the case of a missed dose of Tranexamic Acid injection, it is important to act promptly. If you realize you have missed a scheduled dose, administer it as soon as possible, but avoid doubling the dose to compensate. If it is almost time for your next scheduled dose, simply skip the missed dose and continue with your regular injection schedule. However, if you frequently miss doses, consult your healthcare professional for advice on how to manage your medication regimen effectively.

To administer the Tranexamic Acid injection, clean the injection site with an alcohol swab, insert the needle at a 90-degree angle, and slowly inject the prescribed dose, ensuring the entire medication is delivered before withdrawing the needle.

Here are the conditions and situations when Tranexamic Acid injection should not be administered:

• Allergy or hypersensitivity to Tranexamic Acid or any of its excipients is present.
• Active thromboembolic disease, such as deep vein thrombosis or pulmonary embolism, is diagnosed.
• Patients with a history of arterial or venous thrombosis should avoid this medication.
• Not recommended for individuals with severe renal impairment or end-stage renal disease.
• Should not be used in patients with active hemorrhage due to defective coagulation.
• Contraindicated in patients with disseminated intravascular coagulation (DIC).
• Not suitable for patients undergoing cardiac surgery who are at increased risk of bleeding or thrombosis.
• Should not be administered to patients with a history of seizures or conditions that increase the risk of seizures.
• Avoid use in patients with color vision impairment or those with known or suspected retinal changes.

The side effects of Tranexamic Acid injection may include:

• Nausea and vomiting
• Diarrhea
• Dizziness or lightheadedness
• Headache
• Visual disturbances (blurred vision or double vision)
• Skin rash or itching
• Chest pain or discomfort
• Rare cases of blood clots in veins and arteries.

Following are the precautions and warnings for Tranexamic Acid injection:

• Not recommended for individuals with a known hypersensitivity or allergy to Tranexamic Acid or any excipients in the injection.
• Patients with a history of blood clots, cardiovascular disease, or kidney problems should use with caution as it may increase the risk of complications.
• Requires close monitoring in patients with a history of seizures or epilepsy, as it may lower the seizure threshold.
• Should be used with caution in elderly patients as they may be more susceptible to side effects.
• It is important to ensure adequate fluid intake and monitor for signs of fluid overload, especially in patients with heart or kidney issues.
• Not recommended for long-term use without medical supervision, as prolonged use may increase the risk of thrombosis.
• Patients undergoing surgery or invasive procedures should inform their healthcare provider about Tranexamic Acid usage to prevent excessive bleeding or other complications.

Following are the drug interactions for Tranexamic Acid injection:

• Tranexamic acid may increase the risk of thrombosis when used with oral contraceptives or hormone replacement therapy.
• Concomitant use with anticoagulants like heparin or warfarin may reduce the effectiveness of these drugs.
• Caution is advised when using with fibrinolytic agents, as it can inhibit their action.
• The effect of thrombolytic agents may be reduced when administered with tranexamic acid.
• Antithrombotic drugs, such as aspirin or clopidogrel, may have decreased efficacy when combined with this medication.
• NSAIDs like ibuprofen or naproxen can increase the risk of bleeding when used concurrently.
• It may decrease the absorption of cyclosporine, requiring monitoring and dose adjustments.

Following are the food interactions for Tranexamic Acid injection:

• Avoid consuming alcohol during treatment as it may increase the risk of bleeding and reduce the effectiveness of the medication.
• Grapefruit and grapefruit juice should be consumed with caution as they can interfere with the absorption of Tranexamic Acid, potentially reducing its effectiveness.
• High-fat meals may delay the absorption of Tranexamic Acid, so it is best to avoid heavy, fatty foods before or after receiving the injection.
• Avoid herbal supplements like Ginkgo Biloba and Garlic as they may increase the risk of bleeding when combined with Tranexamic Acid.
• Green leafy vegetables rich in Vitamin K (like spinach, kale) should be consumed in moderation as they can affect blood clotting and interact with the medication's action.
• Avoid excessive Vitamin C supplements as they can interfere with the body's natural blood clotting process and interact with the medication.
• Consult your healthcare provider for specific dietary guidelines, especially if you have a history of kidney or liver disease, as certain food restrictions may be necessary.
• Always inform your healthcare provider about your dietary habits and any supplements you take to ensure the safe and effective use of Tranexamic Acid injection.

Tranexamic Acid injection should be stored in a controlled environment, preferably between 68°F and 77°F (20°C and 25°C), allowing for some flexibility in room temperature storage. Protect the injection from light and ensure it is kept in a safe place, away from children and pets. When storing, keep the medication in its original packaging, tightly sealed, to maintain its integrity and sterility. Always check the expiration date before use and never use the injection if it has expired. For disposal, do not flush or pour the medication down the drain; instead, follow local guidelines or consult a pharmacist for safe disposal methods to minimize environmental impact. Proper disposal ensures the medication is handled responsibly, reducing potential risks associated with improper waste management.

Following are the quick tips for Tranexamic Acid injection:

• Administer the injection as directed by your physician or healthcare professional.
• Ensure the injection is prepared and administered by trained medical staff.
• Follow the prescribed dosage and administration schedule for the best treatment outcome.
• Do not inject intravenously; it should be given slowly into a muscle or vein as instructed.
• Rotate injection sites to minimize discomfort and reduce the risk of skin irritation.
• Inform your doctor if you experience any unusual bleeding or bruising during treatment.
• Store the injection as directed on the packaging, away from direct sunlight and moisture.

Tranexamic acid is a medication that is typically prescribed to treat or prevent excessive blood loss from wounds or during menstrual periods. It is in the category of drugs called fibrinolytics, which help stabilize blood clots and prevent excessive bleeding. While laboratory tests are not required for everyone who takes tranexamic acid, certain monitoring may be done to ensure the safety and effectiveness of the medication. This will depend on several factors, including the prescription of the medication, dosage and duration of treatment, and individual health conditions and comorbidities.Some factors that influence the need for laboratory tests include: