Tasmi (80mg) 14 Tablets

Telmisartan is an angiotensin II receptor blocker (ARB) that selectively blocks the activation of angiotensin II receptors, specifically the AT1 receptors. Its primary mechanism of action is to prevent the binding of angiotensin II, a potent vasoconstrictor hormone, to these receptors. Angiotensin II is involved in regulating blood pressure and fluid balance in the body. By blocking its effects, telmisartan promotes vasodilation, which leads to decreased peripheral resistance and reduced blood pressure. This mechanism helps to lower blood pressure by relaxing blood vessels, allowing for improved blood flow and reducing the workload on the heart.

Angiotensin II Receptor Blocker

Tablet

The following are the uses of Telmisartan 80mg Tablet:

• Used for treating high blood pressure, effectively reducing hypertension.
• Used for managing cardiovascular risks, particularly in patients with type 2 diabetes.
• Used to improve kidney function in patients with diabetic nephropathy.
• Used to reduce protein loss in urine, a sign of kidney damage.
• Used for long-term management of hypertension, offering sustained blood pressure control.
• Used as an alternative for patients intolerant to ACE inhibitors, providing similar benefits.
• Used to lower the risk of heart and kidney complications in specific patient groups.
• Used in combination with other medications for comprehensive cardiovascular care.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Hypertension- Take 1 tablet of Telmisartan 80mg once daily (preferably in the morning) before or after food.
• Heart failure- Take 1 tablet of Telmisartan 80mg once daily, preferably in the morning. If you have kidney failure or are on diuretic pills, your doctor may prescribe a lower dose (e.g., 40mg daily).
• Diabetes with cardiovascular disease- The recommended dose is Telmisartan 80mg once daily. You may take it together with your other diabetes medications. However, it is important to know that Telmisartan does not replace the need for tight blood sugar control in diabetes management

In the case of an overdose of Telmisartan 80mg Tablets, it is important to seek medical advice promptly. Symptoms of an overdose may include low blood pressure, increased heart rate, and dizziness. The severity of the overdose effects can vary depending on the amount ingested and individual factors. Prompt medical intervention is necessary to manage the symptoms and ensure appropriate treatment, which may involve supportive care and monitoring of vital signs. It is crucial to act quickly to mitigate potential health risks.

In the case of a missed dose of Telmisartan 80mg Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or asking someone to remind you to take your medication to maintain the effectiveness of the treatment.

To take Telmisartan 80mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, as directed by your healthcare provider, without crushing or chewing the tablet.

Here is a list of situations or conditions when Telmisartan 80mg Tablet should not be taken:

• Avoid using Telmisartan if you have a known allergy or hypersensitivity to Telmisartan or any other angiotensin II receptor blockers (ARBs).
• Not suitable for individuals with severe liver impairment or biliary obstruction.
• Should not be used in pregnant women, especially during the second and third trimesters, as it can cause harm to the fetus.
• Contraindicated in patients with severe renal impairment or those who are anuric (not producing urine).
• Do not use if you have a condition called bilateral renal artery stenosis (narrowing of the arteries supplying the kidneys).
• Not recommended for children under 18 years of age due to insufficient data on safety and efficacy.
• Avoid using Telmisartan if you have a history of angioedema (swelling of the face, lips, throat, or tongue) with previous use of ARBs or ACE inhibitors.
• Should not be used as a primary treatment for congestive heart failure.

The side effects of Telmisartan 80mg Tablet may include:

• Dizziness
• Fatigue or weakness
• Nausea and vomiting
• Diarrhea
• Cough
• Muscle or joint pain
• Back pain
• Elevated potassium levels in the blood

Following are the precautions and warnings:

• Telmisartan 80mg Tablet should not be used in patients with a known allergy or hypersensitivity to telmisartan or any other angiotensin II receptor blockers (ARBs).
• Patients with a history of severe liver disease or biliary obstruction should exercise caution and undergo regular liver function monitoring while on this medication.
• It may cause dizziness or lightheadedness, so patients should be cautious when performing tasks that require mental alertness, such as driving or operating heavy machinery.
• Telmisartan may cause an increased risk of renal impairment, especially in individuals with existing kidney problems. Close monitoring of kidney function is necessary during treatment.
• This medication can cause fetal harm when used during pregnancy. Women of childbearing age should use effective contraception while taking Telmisartan.
• Breastfeeding women should not use Telmisartan as it may pass into breast milk and harm the nursing infant.
• Patients with a history of heart or blood vessel disease, including conditions like aortic stenosis or renal artery stenosis, should be closely monitored while on this medication.
• Telmisartan can cause hyperkalemia (high potassium levels); regular monitoring of potassium levels is recommended, especially in patients with kidney disease or those taking potassium supplements.

Following are the drug interactions for Telmisartan 80mg Tablet:

• If used with other angiotensin II receptor blockers (ARBs) or angiotensin-converting enzyme (ACE) inhibitors, there is an increased risk of hypotension and impaired kidney function.
• Telmisartan may elevate the blood levels of lithium, leading to lithium toxicity. Close monitoring of lithium levels is necessary.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) might reduce the antihypertensive effect of Telmisartan and increase the risk of kidney dysfunction.
• Telmisartan can enhance the blood pressure-lowering effect of diuretics, which may increase the risk of hypotension.
• When combined with antihypertensive agents like beta-blockers, the blood pressure-lowering effect can be additive.
• The use of Telmisartan with potassium-sparing diuretics or potassium supplements may lead to hyperkalemia. Regular monitoring of potassium levels is advised.
• Drugs that affect the renin-angiotensin system, such as direct renin inhibitors, may increase the risk of hypotension and renal impairment when used concurrently with Telmisartan.

Following are the food interactions to consider with Telmisartan 80mg Tablet:

• Avoid excessive alcohol consumption as it can increase the risk of dizziness and may also affect blood pressure.
• Grapefruit and grapefruit juice should be consumed with caution as they may increase the blood levels of Telmisartan, potentially causing an excessive drop in blood pressure.
• High-salt foods should be limited as Telmisartan is a blood pressure-lowering medication, and a high-salt diet may reduce its effectiveness.
• Potassium-rich foods like bananas, oranges, and spinach should be consumed moderately as Telmisartan can increase potassium levels in the blood.
• Avoid licorice or licorice-containing products as they may decrease the effectiveness of Telmisartan in lowering blood pressure.
• Maintain a balanced diet; consult a dietician if you have any specific dietary concerns while taking Telmisartan.
• Stay hydrated, but avoid excessive fluid intake as it may affect blood pressure and kidney function.
• Follow dietary advice provided by your healthcare provider, especially if you have conditions like diabetes or heart disease.

Telmisartan 80mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to store the tablets in the bathroom or near heat-emitting appliances to preserve their effectiveness. Always adhere to the expiration date indicated on the packaging, and if the medication is no longer needed or has expired, proper disposal is essential. Avoid flushing the tablets down the toilet or sink; instead, consult a pharmacist or healthcare professional for guidance on safe disposal practices. Keep the medication securely stored away from children to prevent accidental consumption.

Following are the quick tips for Telmisartan 80mg Tablet:

• Take the tablet as directed by your doctor, usually once daily.
• Consume the tablet whole with a sufficient amount of water.
• You can take it with or without food, but try to maintain consistency.
• If you have difficulty swallowing, ask your pharmacist about alternative options.
• Do not crush or chew the tablet to avoid altering its effectiveness.
• Store the medication in a cool, dry place, away from direct sunlight.
• Regularly monitor your blood pressure and kidney function while on this medication.

Laboratory monitoring is an essential part of the management of patients taking Telmisartan 80mg. Specific tests and their frequency may vary depending on individual factors such as underlying medical conditions, other medications, and clinical circumstances. The six common lab tests detailed below are frequently required for comprehensive patient monitoring and to ensure patient safety. Firstly, Liver Function Tests (LFTs) are integral to monitoring liver health in patients taking Telmisartan. This is due to the drug's liver metabolism and potential to cause liver damage; ALT, AST, AKP, and bilirubin tests are all critical indicators of liver function and can highlight any signs of injury. Secondly, Kidney Function Tests (KFTs) are necessary to monitor kidney function in patients taking Telmisartan. This is particularly important because this drug can cause kidney impairment in cases of overdose or for patients with preexisting kidney problems. Blood urea nitrogen (BUN) and creatinine (Cr) levels provide crucial insight into overall kidney function. Thirdly, while not a laboratory test, it is vital to regularly monitor the patient's blood pressure, particularly for those with preexisting cardiovascular diseases or hypertension. As a blood pressure-lowering agent, Telmisartan may require dosage adjustments to maintain target blood pressure levels. Furthermore, a Complete Blood Count (CBC) is recommended to monitor any abnormalities in blood cell production, such as anemia. The prevalence of low red blood cell counts or anemia as a side effect of blood pressure medications including Telmisartan underscores the importance of this test. Potassium levels should also be monitored, especially if the patient is already taking potassium-sparing diuretics or other drugs that can affect potassium levels. Telmisartan can increase the risk of low potassium levels, known as hypokalemia. Finally, although less common, excessive sodium levels in the blood, known as hypernatremia, may affect some individuals taking Telmisartan.