Tasmi (40mg) 14 Tablets

Angiotensin II receptor type 1 (AT1) antagonists like Telmisartan are selective and orally active. They reduce end organ responses to angiotensin II by inhibiting the AT1 receptor. This reduces total peripheral resistance and cardiac venous return. The effects of angiotensin-converting enzyme (ACE) inhibitors like nitric oxide (NO) generation, vasodilation, antiproliferative effects, and anti-inflammatory effects are also mediated via the AT1 receptor inhibition. Telmisartan is a lipophilic drug that crosses the blood-brain barrier and reaches higher concentrations in the brain than hydrophilic drugs. Unlike ACE inhibitors, angiotensin II receptor antagonists do not have sexual dimorphism with regard to pharmacokinetics.

Angiotensin II Receptor Blocker (ARB)

Unveiling its multifaceted uses and transformative applications as follows:

• Lowering blood pressure
• Treatment of hypertension
• Reduce the risk of stroke
• Reduce the risk of death after a stroke
• Reduce the risk of heart attack
• Reduce the risk of kidney damage as a result of diabetes
• Reduce vision loss as a result of diabetes
• Reduce risk of cardiovascular mortality
• Reduce the risk of diabetic nephropathy
• Treat arterial hypertensive disorders
• Treatment of hypertension in pregnant women, and women who are breastfeeding
• May be used with diuretics or calcium channel blockers to treat hypertension.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Hypertension- Take 1 tablet of Telmisartan 40mg once daily, preferably in the morning before breakfast.
• Coronary Artery Disease (CAD)- Take 1 tablet of Telmisartan 40mg once daily in conjunction with other heart medications as prescribed by your doctor.
• Congestive Heart Failure (CHF)- Take 1 tablet of Telmisartan 40mg once daily, preferably in the morning before breakfast, in conjunction with other heart medications as prescribed by your doctor.
• Diabetes with Hypertension- Take 1 tablet of Telmisartan 40mg once daily, preferably in the morning before breakfast, along with other anti-diabetic medications as prescribed by your doctor.

Overdosing on Telmisartan can cause symptoms that affect the stomach and kidneys, including nausea, stomach pain, low blood pressure, and kidney problems. Although these symptoms are not life-threatening, it is highly recommended that you seek emergency medical care if you believe you have overdosed. In the emergency room, doctors will conduct a gastric lavage to pump the stomach and remove the extra medication. They may also provide activated charcoal to prevent further absorption of the telmisartan. In more severe cases, dialysis may be necessary to remove the drug from the blood. The healthcare team will provide supportive care and focus on managing symptoms to ensure the patient is stable and comfortable. If you are concerned about an excessive dose of telmisartan or any other medication, please contact your healthcare provider or seek emergency medical care immediately.

If you miss a dose of Telmisartan, it is important to take it as soon as you remember. However, if you remember the missed dose close to the time of your next scheduled dose, it is recommended to skip the missed dose altogether instead of taking double to make up for it. Maintaining a regular dosage schedule ensures you get the maximum benefits from Telmisartan. If you have any concerns or questions about missing a dose, it is best to consult with your healthcare provider for guidance on your specific situation.

Before starting Telmisartan 40mg, ensure you read the medication guide provided by your pharmacist, and if you have any questions, ask your doctor or pharmacist. Telmisartan is usually taken once a day with or without food. Unlike other medications, the effectiveness of Telmisartan does not significantly alter whether you take it with or without food, so consistent consumption is more crucial than meal timing. Remember to swallow the tablet whole with water; do not crush or chew the tablet, as it can alter the drug release and lead to side effects. If you miss a dose, take it as soon as possible unless it is closer to the time for your next dose. In that case, skip the missed dose and continue on your regular schedule. Do not double the dose to catch up. While it is important to take Telmisartan as directed, it is also important to remember that if you feel it necessary to change your dosage or frequency, you should consult your doctor first as they may modify the dosage over time based on your blood pressure response and overall tolerance to the medication. Ensure you monitor your blood pressure regularly, as directed by your doctor, to ensure the medication is working effectively and the dose is appropriately adjusted. If you experience any severe side effects, seek medical attention immediately. These may include severe allergic reactions, chest pain, difficulty breathing, or signs of anaphylaxis. Remember that it is important to adhere to the regimen provided by your healthcare provider when taking Telmisartan 40mg.

Discerning instances where this medication may not be appropriate:

• If you are allergic to Telmisartan or any of the inactive ingredients in the medication, it is vital to inform your doctor.
• If you have diabetes or kidney problems, and your doctor has not prescribed Telmisartan to you, as people with diabetes or kidney issues require special precautions and monitoring while taking Telmisartan.
• If you are pregnant or planning to become pregnant, as Telmisartan is categorized as a FDA Category D drug, and there is a potential risk of harm to a fetus if the mother takes the drug during pregnancy.
• If you are taking specific medications for certain conditions, such as HIV/AIDS, cancer, immunosuppressants, or medications that weaken the immune system, as Telmisartan may interact with these drugs.
• If you are undergoing major surgery or have experienced a recent injury, as consumption of Telmisartan before surgery or after an injury is not recommended.
• If you have unusually low blood pressure or a recent history of recurrent fevers or infections, as Telmisartan can cause low blood pressure as a side effect.

Unraveling the side effects lurking behind this medications are as follows:

• Blurred vision
• Flushing
• Fatigue
• Headache
• Dizziness
• Nausea
• Vomiting
• Diarrhea
• Constipation
• Erectile dysfunction
• Irritability
• Loss of appetite
• Muscle cramps
• Muscle pain

Here are some important precautions and warnings that patients should be aware of:

• Patients with aortic or mitral stenosis, obstructive hypertrophic cardiomyopathy, or ischemic cardiopathy should exercise caution.
• Individuals with unstented unilateral or bilateral renal artery stenosis require careful monitoring.
• Those with ascites due to cirrhosis or refractory ascites should consult their healthcare provider.
• Caution is advised for patients undergoing major surgery or anesthesia.
• Special consideration is required for patients of Black race.
• Caution should be exercised in cases of mild to moderate hepatic and renal impairment.
• Extra care is necessary during lactation.

Drug interactions with telmisartan include:

• Potassium-sparing diuretics (e.g., spironolactone) (may increase the risk of hyperkalemia)
• ACE inhibitors (e.g., enalapril) (may increase the risk of renal impairment and hyperkalemia)
• NSAIDs (e.g., ibuprofen) (may reduce the antihypertensive effect of telmisartan and increase the risk of renal impairment)
• Lithium (may increase lithium levels and risk of toxicity)
• Diuretics (e.g., hydrochlorothiazide) (may enhance the antihypertensive effect)

Store at room temperature, away from moisture and light. Dispose of unused or expired medication through proper pharmaceutical disposal channels.