Telmis-A (80/5mg) 14 Tablets

Telmisartan is a selective antagonist of angiotensin II receptor type AT1, meaning it reduces the responses of organs to angiotensin II. Specifically, by blocking the binding of angiotensin II to the AT1 receptor, telmisartan inhibits the mediated vasoconstriction, secretion of aldosterone, and reabsorption of sodium tubes. All of this reduces the overall vascular resistance and blood pressure, and it does not affect the levels of angiotensin II metabolites nor does it affect the RAS-independent effects of angiotensin II. Amlodipine, on the other hand, is a calcium channel blocker, inhibiting calcium uptake in vascular smooth muscle cells, which reduces the tone of blood vessels, increasing the supply of blood and oxygen to the heart and peripheral organs. This action results in the desired decrease in blood pressure. By blocking the L-type calcium channels, amlodipine causes inhibition of calcium uptake in cardiac and vascular smooth muscle cells, leading to slowed calcium uptake and relaxation of the coronary and peripheral arteries, resulting in increased blood flow and delivery of oxygen to the heart, which is normally suppressed in patients with hypertension and ischemic heart disease.

Telmisartan:

Unveiling its multifaceted uses and transformative applications as follows:

• Telmisartan 80mg is an angiotensin-II-receptor antagonist that helps in the treatment of high blood pressure.
• It works by blocking the hormone angiotensin thereby relaxing the blood vessels.
• This enables the blood to flow more easily around the body and helps lower the blood pressure.
• Amlodipine 5mg is a calcium channel blocker that widens the blood vessels making it easier for the heart to pump blood around the body and help to lower the blood pressure.
• Both the drugs in combination are used to treat high blood pressure.
• Telmisartan is also used to treat kidney diseases in patients with diabetes and to delay kidney failure in patients with diabetes.
• It is also used to reduce the risks of heart attacks and stroke.
• Amlodipine is used to treat angina (chest pain) and other heart problems.
• It is also used to increase blood flow to the heart for people with coronary artery disease.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Telmisartan 80mg-
• Hypertension- Take 1 tablet once a day
• Coronary Artery Disease- Take 1 tablet once a day
• Stroke- Take 1 tablet once a day
• Heart Failure- Take 1 tablet once a day
• Amlodipine 5mg-
• Hypertension- Take 1 tablet once a day

An overdose of Telmisartan 80mg and Amlodipine 5mg can be potentially fatal and requires immediate medical attention. If you or someone else has experienced an overdose of these medications, it is crucial to seek professional help promptly. The specific treatment approach depends on the individual's symptoms and the severity of the overdose. To alleviate symptoms, which may include low blood pressure, congestive heart failure, or respiratory distress, healthcare providers may use intravenous fluids, medications to increase blood pressure, and breathing support. In severe cases or if the patient has impaired kidney function, dialysis may be necessary to help remove the drugs from the body. Additionally, specific medications that counteract the effects of these drugs, such as blood pressure medications administered cautiously in cases of severe hypotension, may be administered. Patients will be closely monitored for any signs of a worsening condition, including vital signs, cardiovascular status, and laboratory values, which may involve blood pressure monitoring, oxygen levels, and kidney function tests. Given the variability of individual responses to drug overdoses, a detailed medical evaluation is crucial to determine the specific treatment required for each patient. Remember, consulting a medical professional immediately is essential if you or someone else has experienced an overdose of these medications.

If you miss a dose of Telmisartan 80mg and Amlodipine 5mg, it is important to take the missed dose as soon as you remember. However, if it is almost time for the next dose, it is best to skip the missed dose altogether since each dose is typically administered once a day. Taking more medicine to make up for the missed dose may result in an overdose and lead to harmful side effects. To avoid missing doses, you can set reminders, keep the medication somewhere visible, or ask your doctor or pharmacist about helpful tips. It is essential to follow the prescribed dosage schedule consistently and accurately to achieve the treatment's full benefit. If you have any confusion or concerns about adjusting the schedule or if you have missed multiple doses, it is always best to reach out to your doctor or pharmacist for professional advice. They may provide helpful tips or guidance on how to get back on track with your medication schedule without compromising your health.

When taking Telmisartan 80mg and Amlodipine 5mg, it is important to follow the instructions provided by your doctor. Here are some general guidelines:

Discerning instances where this medication may not be appropriate:

• This combination of medications should not be used if you have allergies, are pregnant, or have severe kidney disease/kidney failure, low blood pressure (hypotension), impaired liver function, or stenosis of the aortic valve.
• It's imperative to consult with a physician before adjusting, restarting, or stopping any blood pressure medication.
• This medication should not be used without a prescription and medical advice and care should be sought if you experience any unusual symptoms.

Unraveling the side effects lurking behind this medications are as follows:

• Edema (swelling in various parts of the body due to fluid retention.
• Kidney problems (damage to kidney tissues, leading to acute kidney injury.
• Dizziness (a sense of unbalanced feeling or lightheadedness.
• Fatigue (extreme tiredness and lack of energy.
• Joint pain (stiffness and discomfort in joints.
• Gastrointestinal problems (nausea, vomiting, diarrhea, and stomach cramps.
• Heart problems (abnormal heart rate, angina (chest pain) and myocardial infarction (heart attack).
• Breathlessness (shortness of breath during normal activities.

Telmisartan and amlodipine are both oral tablets that are typically taken once daily, with or without food. It is essential to follow the instructions provided by a doctor or pharmacist regarding proper storage and dosing. Telmisartan should be stored at room temperature, away from direct light and moisture, while amlodipine should be stored at room temperature and away from direct light and heat. It is important to keep these medications out of reach and sight of children, pets, and others. If you have any questions or concerns about storing these medications, consult with your doctor or pharmacist.