Telox (300mg/5ml) 120ml Suspension

Telox (300mg/5ml) 120ml Suspension

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  • Manufacturer Platinum Pharmaceuticals (Pvt.) Ltd.
  • Generic Name Oxcarbazepine

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Oxcarbazepine, a 300mg syrup/suspension, exerts its therapeutic effects primarily through its active metabolite, the 10-monohydroxy derivative (MHD). MHD blocks voltage-gated sodium channels, stabilizing hyperexcitable neural membranes, inhibiting repetitive neuronal firing, and reducing propagation of synaptic impulses. This mechanism is crucial in preventing and controlling seizures, as it modulates the excessive electrical activity in the brain associated with epilepsy. By selectively inhibiting sodium channel activity, oxcarbazepine's MHD metabolite plays a key role in managing various types of seizures, making it an effective medication for epilepsy treatment.

  • Ingredients

    Oxcarbazepine
  • Drug Class

    Anticonvulsant medication

  • Dosage Form

    Suspension

  • Uses

    The following are the uses of Oxcarbazepine 300mg Syrup/Suspension:

    • Used for managing partial seizures in adults and children
    • Used to treat certain types of epilepsy
    • Used to control seizures associated with Lennox-Gastaut syndrome
    • Used for stabilizing mood and treating bipolar disorder
    • Used as an add-on therapy to enhance seizure control
    • Used to provide flexible dosing options for patients
    • Used for easy administration, especially for those who have difficulty swallowing tablets
    • Used as a long-term maintenance therapy to prevent seizure recurrence
  • In case of Overdose

    In the case of an overdose of Oxcarbazepine 300mg Syrup/Suspension, immediate medical attention is required. Symptoms may include severe dizziness, extreme drowsiness, slurred speech, and impaired coordination. Promptly seek emergency medical care and provide the healthcare provider with details of the medication, including the amount ingested and the time of overdose. Quick action can help manage potential complications and ensure appropriate treatment.

  • Missed Dose

    In the case of a missed dose of Oxcarbazepine 300mg Syrup/Suspension, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for a missed one, as this may increase the risk of side effects. It is important to maintain a consistent medication routine, but if you frequently miss doses, consult your healthcare provider for advice on how to improve adherence.

  • How To Use

    To administer Oxcarbazepine 300mg Syrup/Suspension, shake the bottle well, measure the prescribed dose with an oral syringe or measuring cup, and take it orally, preferably at the same time each day, following the dosage instructions provided by your healthcare professional.

  • When Not to Use

    Following are the conditions when Oxcarbazepine 300mg Syrup/Suspension should not be used:

    • Do not use if you are allergic to Oxcarbazepine or any other similar medications.
    • Avoid if you have a history of bone marrow suppression or blood disorders.
    • Not suitable for individuals with a history of hypersensitivity reactions to carbamazepine.
    • Should not be used in patients with a rare genetic condition called porphyria.
    • Contraindicated in individuals with severe liver or kidney disease.
    • Do not administer to children under 2 years of age.
    • Not recommended for individuals with a history of depression or suicidal thoughts/behavior.
  • Side Effects

    The side effects of Oxcarbazepine 300mg Syrup/Suspension may include:

    • Dizziness or lightheadedness
    • Fatigue or drowsiness
    • Nausea and vomiting
    • Headache
    • Skin rashes or itching
    • Loss of appetite
    • Blurred or double vision
    • Balance or coordination problems
  • Precautions & Warnings

    Following are the precautions and warnings for Oxcarbazepine 300mg Syrup/Suspension:

    • Do not use this medication if you are allergic to Oxcarbazepine or related medications like Carbamazepine.
    • Oxcarbazepine can cause serious skin reactions; seek medical attention if you develop a rash, hives, or blisters.
    • Regular blood tests are required to monitor liver and kidney function, especially during long-term treatment.
    • This medication may cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.
    • Alcohol consumption should be avoided as it can increase the risk of side effects.
    • Consult your doctor if you have a history of kidney or liver problems, as dosage adjustments may be necessary.
    • Do not abruptly stop taking Oxcarbazepine without medical advice, as it may lead to withdrawal seizures.
    • Inform your healthcare provider about all the medications you are taking to avoid potential drug interactions.
  • Drug Interactions

    Following are the drug interactions for Oxcarbazepine 300mg Syrup/Suspension:

    • Concomitant use with other antiepileptic drugs (AEDs) like phenytoin, carbamazepine, or valproic acid may alter their plasma levels, requiring dosage adjustments.
    • Oxcarbazepine can decrease the effectiveness of hormonal contraceptives, including birth control pills, patches, or rings, increasing the risk of unintended pregnancy.
    • Drugs that induce liver enzymes, such as rifampicin, may reduce oxcarbazepine levels, possibly requiring dosage adjustments.
    • The combination with lamotrigine may increase the risk of skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis.
    • Alcohol consumption should be avoided as it may increase the risk of adverse effects and impair cognitive function.
    • Oxcarbazepine may increase the blood levels of certain antidepressants, like selective serotonin reuptake inhibitors (SSRIs), potentially leading to increased side effects.
    • This medication may affect the metabolism of lithium, leading to elevated lithium levels and increased risk of lithium toxicity.
  • Food Interactions

    Following are the food interactions for Oxcarbazepine 300mg Syrup/Suspension:

    • Alcohol consumption should be avoided as it can increase the sedative effects, leading to enhanced drowsiness and dizziness.
    • Grapefruit and grapefruit juice are to be avoided as they may influence the levels of Oxcarbazepine in the blood by inhibiting the enzyme CYP3A4, potentially increasing the risk of side effects.
    • High-fat meals might slightly decrease the absorption of Oxcarbazepine, but this effect is not considered clinically significant.
    • Avoid caffeine-rich foods and beverages as they may reduce the seizure threshold, especially in individuals with epilepsy.
    • Oxcarbazepine can be taken with or without food, but maintaining a consistent routine is advisable.
    • Avoid consuming large amounts of cranberry products as they may interact with Oxcarbazepine, potentially affecting its metabolism.
    • Inform your healthcare provider about your dietary habits to ensure the medication's effectiveness and safety.
    • Always follow the dosage instructions provided by your doctor or pharmacist.
  • Storage/Disposal

    Oxcarbazepine 300mg Syrup/Suspension should be stored in a secure and controlled environment, preferably in a locked cabinet or a designated medication storage area, maintaining a cool and dry atmosphere. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial to avoid exposing the medication to direct sunlight, heat, or moisture, as these factors can compromise its effectiveness. Always check the expiration date, and if the syrup has expired or is no longer needed, proper disposal is essential. Do not dispose of it in household trash or pour it down the drain; instead, follow local guidelines for pharmaceutical waste disposal or consult a healthcare professional for guidance on safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption.

  • Quick Tips, if any

    Following are the quick tips for Oxcarbazepine 300mg Syrup/Suspension:

    • Follow the dosage instructions provided by your doctor or pharmacist.
    • Administer the syrup as directed, typically twice daily.
    • Shake the bottle vigorously before each use to ensure proper mixing.
    • Use the provided measuring device for accurate dosing.
    • Consume the syrup with a full glass of water for better absorption.
    • Avoid missing doses; take it at the same time each day for consistency.
    • Store the syrup at room temperature, away from light and moisture.

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