Terbizam (125mg) 10 Tablets

Terbizam (125mg) 10 Tablets

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  • Manufacturer LEO PHARMACEUTICALS (PVT.) LTD.
  • Generic Name Terbinafine

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Laboratory Screening
  • Description

    Terbinafine 125mg Tablet primarily works by interfering with the synthesis of ergosterol, a crucial component of fungal cell membranes. It specifically targets an enzyme called squalene epoxidase, which plays a vital role in the biosynthetic pathway leading to ergosterol production. By inhibiting this enzyme, terbinafine disrupts the fungal cell membrane integrity, leading to impaired membrane function and ultimately the death of the fungal cells. This selective inhibition of squalene epoxidase makes terbinafine highly effective against various types of fungi, including dermatophytes, which are responsible for common skin and nail infections.

  • Ingredients

    Terbinafine
  • Drug Class

    Antifungal

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Terbinafine 125mg Tablet:

    • Used for treating fungal infections of the skin, hair, and nails.
    • Used for managing athlete's foot, jock itch, and ringworm.
    • Used for preventing the spread of fungal infections to healthy skin.
    • Used for relieving itching, redness, and discomfort associated with fungal infections.
    • Used for improving skin and nail appearance by clearing the infection.
    • Used for long-term treatment to ensure complete eradication of the fungus.
    • Used for preventing recurrence of fungal infections in susceptible individuals.
    • Used for maintaining skin and nail health after successful treatment.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Onychomycosis- 250mg - 500mg once or twice a day for 6 weeks
    • Tinea corporis- 125mg - 250mg once a day for 2 - 4 weeks
    • Tinea pedis- 125mg - 250mg once a day for 2 weeks
    • Tinea cruris- 125mg - 250mg once a day for 2 weeks
    • Scaling skin lesions of dermatophytosis- 125mg - 250mg once a day for 2 - 4 weeks
  • In case of Overdose

    In the case of an overdose of Terbinafine 125mg Tablets, it is important to recognize the potential symptoms and take appropriate action. Common signs may include nausea, vomiting, stomach pain, and an increase in liver enzyme levels. If an overdose is suspected, seek medical advice immediately. Prompt treatment and monitoring are essential to manage any adverse effects and ensure the patient's well-being. Timely intervention can help prevent potential complications and support a full recovery.

  • Missed Dose

    In the case of a missed dose of Terbinafine 125mg Tablet, it is important to take the dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is recommended to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare provider for guidance on how to get back on track with your medication regimen safely. It is advisable to set reminders or keep the medication in a visible place to help you remember to take it as prescribed.

  • How To Use

    To take Terbinafine 125mg Tablet, swallow the tablet whole with a full glass of water, preferably with or after a meal, once daily as directed by your healthcare professional.

  • When Not to Use

    Following are the conditions when Terbinafine 125mg Tablet should not be used:

    • Should not be used in individuals with a known allergy to Terbinafine or other antifungal medications.
    • Not recommended for individuals with severe liver or kidney disease.
    • Contraindicated in patients with a history of blood disorders or bone marrow suppression.
    • Avoid using in patients with a history of lupus erythematosus.
    • Not suitable for individuals with a history of heart disease or chest pain.
    • Should not be used during pregnancy or breastfeeding.
  • Side Effects

    The side effects of Terbinafine 125mg Tablet may include:

    • Stomach pain or discomfort
    • Diarrhea
    • Nausea and vomiting
    • Loss of appetite
    • Headache
    • Skin rash or itching
    • Abnormal liver function tests
    • Taste disturbances
  • Precautions & Warnings

    Following are the precautions and warnings for Terbinafine 125mg Tablet:

    • Do not use if you are allergic to terbinafine or any other antifungal medications.
    • This medication may affect liver function, so it is important to monitor liver enzymes regularly, especially during long-term treatment.
    • Patients with existing liver or kidney disease should use with caution and under medical supervision.
    • Inform your doctor about any other medications you are taking, as terbinafine may interact with certain drugs.
    • Avoid alcohol consumption during treatment as it may increase the risk of liver-related side effects.
    • Terbinafine may cause dizziness or drowsiness; avoid driving or operating heavy machinery until you know how it affects you.
    • Not recommended for use in pregnant or breastfeeding women unless the potential benefits outweigh the risks.
    • Keep this medication out of reach of children and pets, and store it in a cool, dry place.
  • Drug Interactions

    Following are the drug interactions for Terbinafine 125mg Tablet:

    • Avoid with strong CYP450 inducers like rifampin, as it can reduce terbinafine levels and decrease effectiveness.
    • Concomitant use with alcohol may increase the risk of liver-related side effects.
    • Terbinafine may increase the effects of warfarin and other anticoagulants, requiring closer monitoring of blood clotting.
    • The risk of side effects may increase when taken with certain antidepressants like SSRIs or tricyclic antidepressants.
    • Drugs that prolong the QT interval, such as amiodarone, should be used cautiously due to potential cardiac effects.
    • Antifungal medications like fluconazole can increase terbinafine levels, potentially leading to increased side effects.
    • May reduce the effectiveness of hormonal contraceptives, requiring additional contraceptive methods.
  • Food Interactions

    Following are the food interactions to consider with Terbinafine 125mg Tablet:

    • Grapefruit and grapefruit juice consumption should be avoided as they can increase the levels of Terbinafine in the blood, potentially leading to increased side effects.
    • Alcohol intake is not recommended, as it may worsen side effects like dizziness and fatigue.
    • Fatty meals can slow down the absorption of Terbinafine, delaying its effectiveness.
    • Caffeine-rich foods and beverages may increase the metabolism of Terbinafine, reducing its efficacy.
    • Avoid foods high in salt and sugar, as they can interfere with the medication's effectiveness in treating fungal infections.
    • Some dairy products, particularly those rich in calcium, can interact with Terbinafine, reducing its absorption.
    • Certain types of nuts and seeds, like flaxseeds and walnuts, may have natural antifungal properties that could potentially interact with Terbinafine's action.
    • Spicy foods may exacerbate side effects like stomach discomfort and nausea when taken with Terbinafine.
  • Storage/Disposal

    Terbinafine 125mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area. Keep the tablets in their original container, tightly sealed, to maintain their integrity and protect them from moisture and light. It is crucial to store the medication at room temperature, avoiding exposure to extreme heat or cold, as this can impact its effectiveness. Always check the expiration date before using the tablets, and never use them beyond the expiry date. When disposing of unused or expired tablets, do not flush them down the toilet or throw them into the trash. Instead, follow local guidelines for medication disposal or consult a pharmacist who can provide guidance on safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption, ensuring their safety.

  • Quick Tips, if any

    Following are the quick tips for Terbinafine 125mg Tablet:

    • Start your treatment early for better results and to prevent the infection from spreading.
    • Take the tablet with a full glass of water, preferably with a meal.
    • Complete the full course of medication, even if symptoms disappear.
    • Maintain good hygiene and keep the affected area clean and dry.
    • Avoid sharing personal items like towels, socks, or shoes to prevent the spread of infection.
    • Inform your doctor if you have any liver or kidney problems before taking this medication.
    • Store the tablets in a cool, dry place, away from direct sunlight and moisture.
  • Laboratory Screening

    Terbinafine Hydrochloride 125mg is a medication prescribed to treat fungal infections of the skin and nails. While the need for laboratory tests during medication is not mandatory for everyone, it is vital to consult with a healthcare provider to determine if any tests are required based on your specific medical history and current health. Your doctor may suggest a range of laboratory tests under certain circumstances:

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