Tetra-derm ER (100mg) 10 Tablets

Minocycline, a tetracycline antibiotic, primarily exerts its antibacterial action by inhibiting protein synthesis in susceptible bacteria. It achieves this by binding to the 30S and 50S ribosomal subunits, disrupting the binding of aminoacyl-tRNA to the RNA acceptor site. This binding interferes with the translocation of peptidyl-tRNA from the A-site to the P-site, ultimately hindering bacterial protein synthesis. Minocycline is lipophilic, allowing it to penetrate the bacterial cell wall and accumulate intracellularly, where it targets the ribosomes. This mechanism selectively affects bacterial protein synthesis while minimizing interference with host cell processes.

Tetracycline Antibiotic

Tablet

The following are the uses of Minocycline 100mg Tablet:

• Used for treating bacterial infections such as pneumonia, skin infections, and urinary tract infections.
• Used for acne control, reducing inflammation and clearing breakouts.
• Used for respiratory tract infections like bronchitis and sinusitis.
• Used for preventing and treating infections in bite wounds or scratches.
• Used for certain sexually transmitted infections like chlamydia.
• Used for rheumatoid arthritis to control inflammation and slow progression.
• Used for Lyme disease, a tick-borne bacterial infection.
• Used for reducing symptoms of gum disease and promoting oral health.

In the case of an overdose of Minocycline 100mg Tablets, individuals may experience a range of symptoms, including nausea, vomiting, and diarrhea. Excessive consumption can lead to severe gastrointestinal distress and potential liver damage. Prompt action is necessary; contact a healthcare professional or poison control center immediately for guidance. They will provide specific instructions to mitigate the effects of the overdose and ensure appropriate medical care is administered without delay. It is crucial to seek assistance promptly to address any potential health risks.

In the case of a missed dose of Minocycline 100mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen. Consult your healthcare provider if you have any concerns or questions regarding missed doses.

To take Minocycline 100mg Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, either with or without food, as directed by your healthcare professional.

Here are the conditions and situations when Minocycline 100mg Tablet should not be taken:

• Avoid using if you have a known allergy to Minocycline or other tetracycline antibiotics.
• Do not take this medication if you are pregnant or breastfeeding, as it can harm the developing fetus and may pass into breast milk.
• Contraindicated in children below 8 years of age due to the risk of permanent tooth discoloration.
• Should not be used by individuals with severe liver or kidney disease, as it may worsen these conditions.
• Avoid using if you have a history of systemic lupus erythematosus (SLE), as it can trigger a flare-up.
• Do not take this medication if you have porphyria, a rare genetic enzyme disorder.
• Not suitable for individuals with a history of intracranial hypertension (increased pressure in the skull).
• Minocycline should not be used in patients with a known or suspected yeast infection, as it is not effective against fungi.
• Do not take this medication if you have a history of esophageal stricture or disorders that affect swallowing.
• Avoid using if you have a history of myasthenia gravis, as it can worsen muscle weakness.

The side effects of Minocycline 100mg Tablet may include:

• Dizziness or lightheadedness
• Nausea and vomiting
• Diarrhea or loose stools
• Skin rash or itching
• Photosensitivity (increased sensitivity to sunlight)
• Headache
• Fatigue and weakness
• Loss of appetite

Following are the precautions and warnings for Minocycline 100mg Tablet:

• Avoid prolonged exposure to sunlight or artificial UV rays, as Minocycline may increase photosensitivity, leading to sunburns.
• Not recommended for individuals with a history of liver or kidney disease; regular monitoring is necessary.
• May cause dizziness; patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• Avoid taking with dairy products or antacids containing aluminum, calcium, or magnesium, as these can reduce the absorption of Minocycline.
• Not suitable for children under 8 years old and should be used with caution in adolescents due to potential risks of tooth discoloration and bone development issues.
• May reduce the effectiveness of birth control pills; alternative contraceptive methods are recommended.
• Inform your doctor if you have a history of autoimmune diseases or lupus before taking Minocycline.
• Discontinue use and seek medical attention if you experience severe diarrhea, abdominal pain, or allergic reactions.

Following are the drug interactions for Minocycline 100mg Tablet:

• Antacids containing aluminum, calcium, or magnesium can reduce the absorption of Minocycline, so they should be taken at least 2 hours apart.
• Minocycline may decrease the effectiveness of oral contraceptives, leading to breakthrough bleeding and potential contraceptive failure.
• The drug can increase the anticoagulant effect of warfarin, necessitating close monitoring of prothrombin time.
• It may reduce the efficacy of penicillins and cephalosporins, potentially decreasing their antibacterial action.
• Concomitant use with methoxyflurane can result in severe renal toxicity, so it should be avoided.
• Minocycline may increase methotrexate levels, raising the risk of methotrexate toxicity.
• It can also enhance the nephrotoxic effects of nephrotoxic drugs like cisplatin and carboplatin.

Following are the food interactions for Minocycline 100mg Tablet:

• Dairy products like milk, yogurt, and cheese should be avoided as they can decrease the absorption of Minocycline, reducing its effectiveness. Consume these products at least 2 hours before or after taking the medication.
• Avoid taking the tablet with meals high in calcium, iron, magnesium, or aluminum, as these minerals can bind to Minocycline and reduce its absorption. This includes antacids and mineral supplements.
• Grapefruit and grapefruit juice are to be avoided as they can alter the metabolism of Minocycline, potentially leading to increased side effects.
• Alcohol consumption should be minimized or avoided as it may increase the risk of side effects such as dizziness and stomach discomfort.
• Caffeinated beverages like coffee and tea might interfere with the absorption of Minocycline, so it's best to limit their intake around the time of medication.
• Vitamin A supplements and foods rich in vitamin A (like liver) should be used with caution as Minocycline can potentially increase vitamin A levels in the body.
• Avoid consuming foods or drinks with a high-fat content, as they can slow down the absorption and effectiveness of the medication.
• Always take the tablet with a full glass of water to ensure proper administration and reduce the risk of esophageal irritation.

Minocycline 100mg Tablets should be stored in a cool and dry place, preferably at room temperature, away from direct exposure to sunlight, heat, and moisture. It is crucial to keep the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. Always check the expiration date on the packaging, and do not use the medication if it is past its expiry. When disposing of unused or expired tablets, do not flush them down the toilet or pour them into drains. Instead, follow local guidelines or consult a pharmacist for appropriate disposal methods to ensure environmental safety. Keep the medication securely stored away from children to prevent accidental consumption.

Following are the quick tips for Minocycline 100mg Tablet:

• Store the tablets in a cool, dry place away from direct sunlight and moisture.
• Take the tablet with a full glass of water to ensure proper swallowing.
• Minocycline can make your skin more sensitive to sunlight, so avoid excessive sun exposure.
• Avoid taking dairy products or antacids within 2-3 hours of taking the tablet for better absorption.
• Complete the full course of medication as prescribed, even if you feel better earlier.
• Inform your doctor about any other medications you are taking to prevent potential interactions.
• Seek immediate medical attention if you experience severe allergic reactions or skin rashes.