Theo-Dur (200mg) 30 Tablets

Theophylline 200mg tablets primarily exert their therapeutic effects through multiple mechanisms of action. It acts as a phosphodiesterase inhibitor, which leads to increased intracellular concentrations of cyclic adenosine monophosphate (cAMP). This elevation in cAMP relaxes bronchial smooth muscles, reduces airway resistance, and improves airflow to the lungs. Additionally, theophylline enhances diaphragmatic contractility, which aids in improving respiratory function. It also possesses anti-inflammatory properties by inhibiting the release of inflammatory mediators such as histamine and leukotrienes, thereby reducing airway inflammation. Theophylline's ability to stabilize mast cell membranes further contributes to its anti-inflammatory action. By combining these mechanisms, theophylline effectively helps in managing respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD).

Bronchodilator.

Tablet

The following are the uses of Theophylline 200mg Tablet:

• Used for treating respiratory conditions like chronic asthma and chronic obstructive pulmonary disease (COPD).
• Used to relax and open up tight airways, making breathing easier.
• Used to reduce wheezing, coughing, and shortness of breath associated with asthma.
• Used for long-term management of asthma and COPD to prevent symptoms and flare-ups.
• Used as a bronchodilator to improve lung function and airflow.
• Used in combination with other asthma medications for better control of symptoms.
• Used to provide relief during asthma attacks or periods of increased symptoms.

In the case of an overdose of Theophylline 200mg Tablets, individuals may experience symptoms such as nausea, vomiting, rapid heartbeat, and seizures. It is important to recognize the signs of overdose, which can include increased heart rate, restlessness, and gastrointestinal issues. Promptly seeking medical assistance is vital if an overdose is suspected. Treatment for an overdose may involve gastric lavage, administration of activated charcoal, and supportive care to manage symptoms and prevent further complications. Timely intervention can significantly impact the outcome of an overdose.

In the case of a missed dose of Theophylline 200mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Never take extra doses to make up for a missed one, as this may lead to an overdose. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen. Consult your healthcare provider if you have any concerns or questions about managing missed doses.

To take Theophylline 200mg Tablets, swallow the tablet whole with a full glass of water, typically twice a day, following the exact dosage instructions provided by your healthcare professional, ensuring you take it consistently at evenly spaced intervals for optimal effectiveness.

Here are the conditions and situations when Theophylline 200mg Tablet should not be taken:

• Avoid using if you have a known allergy to Theophylline or related medications.
• Do not take if you have a history of seizures or epilepsy.
• Contraindicated in individuals with stomach ulcers or gastrointestinal bleeding.
• Should not be used in patients with severe heart conditions, such as unstable angina or recent heart attack.
• Avoid using if you have high blood pressure that is not well controlled.
• Not recommended for individuals with liver disease or impaired liver function.
• Do not consume excessive alcohol while taking Theophylline tablets.
• Should not be used in patients with a history of hyperthyroidism or overactive thyroid.
• Contraindicated during the breastfeeding period.

The side effects of Theophylline 200mg Tablet may include:

• Nausea and vomiting
• Headache
• Insomnia and restlessness
• Rapid or irregular heartbeat (palpitations)
• Nervousness and anxiety
• Diarrhea
• Muscle twitching or tremors

Following are the precautions and warnings for Theophylline 200mg Tablet:

• This medication should be used with caution in patients with a history of seizures, as it may lower the seizure threshold.
• Regular monitoring of blood theophylline levels is essential to ensure the dose is within the therapeutic range and to minimize side effects.
• Patients with liver or kidney disease should be closely monitored as these conditions can affect theophylline metabolism.
• Theophylline can interact with various medications, including antibiotics, antifungal drugs, and other bronchodilators, so doctors should be informed about all medications being taken.
• Patients should avoid consuming large amounts of caffeine while taking theophylline as it can increase side effects.
• It may cause dizziness or lightheadedness, so patients should exercise caution when performing tasks requiring alertness, such as driving or operating machinery.
• Not recommended for use in children under 12 years old unless prescribed by a doctor.

Following are the drug interactions for Theophylline 200mg Tablet:

• Erythromycin, ciprofloxacin, and other CYP1A2 inhibitors can increase theophylline levels, leading to toxicity.
• Carbamazepine and rifampin, as CYP450 enzyme inducers, decrease theophylline levels, reducing its effectiveness.
• Theophylline may increase the effects of stimulants like amphetamines, leading to potential cardiovascular side effects.
• Beta-blockers, such as propranolol, may have their effects reduced by theophylline, requiring monitoring.
• Anticoagulants like warfarin may have their action enhanced, increasing bleeding risk.
• Phenytoin and phenobarbital can decrease theophylline levels, requiring dosage adjustments.
• Quinolone antibiotics may increase theophylline concentrations, necessitating close observation.

Following are the food interactions for Theophylline 200mg Tablet:

• Avoid consuming excessive amounts of caffeine-containing foods and beverages, such as coffee, tea, chocolate, and energy drinks, as they can increase the side effects of Theophylline, leading to increased heart rate and nervousness.
• Grapefruit and grapefruit juice should be consumed with caution as they may alter the metabolism of Theophylline, potentially increasing its levels in the blood and the risk of side effects.
• Avoid high-fat meals as they can decrease the absorption of Theophylline, leading to reduced effectiveness.
• Alcohol can increase the risk of side effects, especially gastrointestinal issues, and should be consumed in moderation or avoided.
• Avoid consuming large amounts of spicy foods as they may exacerbate stomach-related side effects like nausea and stomach upset.
• Avoid smoking as it can decrease the effectiveness of Theophylline by altering its metabolism.
• Always ensure you are well-hydrated when taking Theophylline, as dehydration can affect the drug's distribution and elimination from the body.
• Consult your healthcare provider for specific dietary recommendations and adjustments based on your medical condition and response to the medication.

Theophylline 200mg Tablets should be stored in a cool and dry environment, preferably at room temperature, ensuring protection from direct sunlight and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. It is crucial to avoid exposing the medication to extreme temperatures, so steer clear of storing it in hot places like near stoves or inside bathrooms with high humidity. Always check the expiration date, and if the tablets are past their prime or no longer needed, do not flush them or pour them down the drain. Consult a pharmacist or healthcare professional for guidance on safe disposal methods. Additionally, exercise caution to keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Theophylline 200mg Tablet:

• Always take the tablet as directed by your doctor; do not adjust the dosage without medical advice.
• Ensure you swallow the tablet whole with a full glass of water, do not crush or chew.
• Maintain a consistent daily routine for taking the medication.
• If you experience nausea, taking the tablet with food may help alleviate discomfort.
• Avoid missing doses; take it as soon as you remember if you forget a dose.
• Inform your doctor if you have liver or kidney disease, as dosage adjustments may be required.
• Store the medication at room temperature, away from moisture and heat.