Theramox-500 (500mg) 100 Capsules

Moxifloxacin, a fluoroquinolone antibiotic, exerts its bactericidal effect by inhibiting two crucial enzymes in susceptible bacteria. It primarily targets DNA gyrase and topoisomerase IV, enzymes responsible for DNA replication and repair. By binding to these enzymes, Moxifloxacin interferes with the bacteria's ability to unwind and replicate DNA, leading to the inhibition of bacterial cell division. This mechanism selectively targets bacterial topoisomerases, disrupting the integrity of bacterial DNA and ultimately resulting in bacterial cell death. The specificity of Moxifloxacin's action helps to minimize interference with human cellular processes, making it an effective treatment for various bacterial infections.

Fluoroquinolone antibiotic.

Capsule

The following are the uses of Moxifloxacin Capsule:

• Used for treating respiratory infections like pneumonia, bronchitis, and sinusitis.
• Used for bacterial infections in the lungs.
• Used for skin and soft tissue infections.
• Used for intra-abdominal infections.
• Used for treating urinary tract infections.
• Used for certain types of eye infections.
• Used for community-acquired bacterial infections.
• Used for its potent bactericidal activity against a wide range of pathogens.

In the case of an overdose of Moxifloxacin Capsules, individuals may experience an exacerbation of the drug's side effects. Symptoms could include heightened gastrointestinal issues such as nausea, vomiting, and diarrhea. Central nervous system reactions may also occur, leading to headaches, dizziness, and in severe cases, seizures. It is important to seek medical advice promptly if an overdose is suspected, as the healthcare provider can recommend appropriate treatment and monitoring based on the individual's condition.

In the case of a missed dose of Moxifloxacin Capsule, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, consult your healthcare professional for advice, as they may recommend adjusting your dosage or provide specific instructions to ensure you receive the appropriate treatment.

To take Moxifloxacin Capsule, swallow the capsule whole with a full glass of water, preferably at the same time each day, as directed by your healthcare professional, without chewing or crushing the capsule.

Following are the conditions when Moxifloxacin Capsule should not be used:

• Should not be used in individuals with a known allergy to Moxifloxacin or other quinolone antibiotics.
• Contraindicated in patients with a history of myasthenia gravis as it can worsen muscle weakness.
• Not recommended for individuals with a history of tendon disorders or tendon rupture related to previous quinolone use.
• Avoid in patients with a prolonged QT interval or a known heart rhythm disorder.
• Should not be used in patients with epilepsy or other seizure disorders.
• Contraindicated in individuals with liver disease or impaired liver function.
• Not suitable for children and adolescents under 18 years of age, as the safety and efficacy have not been established in this age group.
• Avoid in pregnant and breastfeeding women due to potential risks to the fetus and infant.
• Should not be used in patients with a history of sensitivity to any other components in the capsule formulation.

The side effects of Moxifloxacin Capsule may include:

• Diarrhea
• Nausea and vomiting
• Dizziness
• Headache
• Skin rash or itching
• Joint and muscle pain
• Fatigue and weakness
• Insomnia

Following are the precautions and warnings for Moxifloxacin Capsule:

• Not recommended for individuals with a known hypersensitivity or allergy to Moxifloxacin or other quinolone antibiotics.
• Should be used with caution in patients with a history of seizures or conditions that increase the risk of seizures, as it may lower the seizure threshold.
• Patients are advised to avoid excessive sunlight or UV exposure as Moxifloxacin can increase sensitivity to sunlight.
• May cause dizziness or lightheadedness, so patients should be cautious when performing activities that require alertness, such as driving or operating machinery.
• Caution is advised in patients with kidney or liver disease, as dosage adjustments may be necessary.
• Should not be used in children, adolescents, pregnant women, or breastfeeding mothers unless the potential benefits outweigh the risks.
• It is important to complete the full course of treatment as prescribed, even if symptoms improve before the medication is finished.

Following are the drug interactions for Moxifloxacin Capsule:

• Avoid concurrent use with other drugs that prolong the QT interval (e.g., certain antiarrhythmics, antipsychotics, or antidepressants), as this may increase the risk of serious cardiac arrhythmias.
• The effectiveness of live bacterial vaccines (e.g., typhoid vaccine) may be reduced, so separate administration by several days.
• Moxifloxacin may increase the serum concentration of Ciclosporin, potentially requiring dose adjustment.
• Theophylline levels may be elevated, leading to increased risk of toxicity. Close monitoring is necessary.
• Warfarin and other anticoagulants may have enhanced effects, requiring close monitoring of coagulation parameters.
• Probenecid can increase the concentration of Moxifloxacin, potentially increasing the risk of side effects.
• Antacids containing multivalent cations (e.g., aluminum, magnesium, calcium) may reduce the absorption of Moxifloxacin, so separate administration by at least 4 hours.

Following are the food interactions for Moxifloxacin Capsule:

• Avoid excessive caffeine intake, as Moxifloxacin can increase the effects of caffeine and lead to overstimulation and anxiety.
• Grapefruit and grapefruit juice should be consumed with caution as they may increase the concentration of Moxifloxacin in the blood, potentially enhancing its side effects.
• Dairy products like milk, yogurt, and cheese should be avoided as they can decrease the absorption of Moxifloxacin, reducing its effectiveness.
• Avoid alcohol consumption during treatment as it can increase the risk of liver problems and may also intensify the side effects of Moxifloxacin.
• Antacids containing magnesium or aluminum may decrease the absorption of Moxifloxacin, so it is recommended to separate the doses of these medications by at least 4 hours.
• Vitamin K-rich foods like spinach, kale, and broccoli may reduce the effectiveness of Moxifloxacin, so it's best to consult a healthcare professional for dietary advice during treatment.
• Iron supplements and iron-rich foods such as red meat and spinach can interfere with Moxifloxacin absorption, so they should be taken at different times, ideally 2 hours apart.
• Avoid high-fat meals as they can delay the absorption of Moxifloxacin, potentially affecting its efficacy.

Moxifloxacin Capsules should be stored in a cool, dry place, preferably at room temperature between 68°F and 77°F (20°C and 25°C). Protect the capsules from light and moisture by keeping them in their original packaging or container. Do not store in the bathroom or any areas with high humidity, as it may affect the medication's quality. Always check the expiration date before using any medication. Proper disposal of unused or expired capsules is crucial; do not flush them down the toilet or throw them into the trash. Contact your pharmacist or healthcare provider for guidance on safe disposal methods to minimize environmental impact. Keep the capsules out of the reach of children and pets to prevent accidental ingestion.

Following are the quick tips for Moxifloxacin Capsule:

• Take the capsule at the same time each day as directed by your healthcare professional.
• Swallow the capsule whole with a full glass of water, preferably on an empty stomach.
• Avoid taking it with dairy products, antacids, or mineral supplements as they may interfere with absorption.
• Complete the full prescribed course, even if you feel better, to ensure the infection is completely treated.
• Store the capsules at room temperature, away from moisture and direct sunlight.
• Do not crush or chew the capsule; it should be swallowed intact.
• Contact your doctor immediately if you experience severe diarrhea, rash, or any allergic reactions.