Thyronorm (125mcg) 100 Tablets

Levothyroxine is a synthetic thyroid hormone that is chemically identical to the naturally occurring thyroxine (T4) produced by the thyroid gland. Its mechanism of action is straightforward; it acts as a replacement or supplemental source of thyroid hormone in the body. When administered, levothyroxine replaces or supplements the natural thyroid hormones T4 and T3 (triiodothyronine). This is especially important in individuals with hypothyroidism, where the thyroid gland does not produce enough thyroid hormones. By providing the body with the necessary thyroid hormones, levothyroxine restores the hormonal balance, thereby alleviating the symptoms associated with hypothyroidism. It enhances cellular metabolism, stimulates the production of enzymes and proteins, and increases oxygen consumption, ultimately regulating various physiological processes such as growth, development, and metabolism.

Levothyroxine

Thyroid hormone replacement.

Tablet

The following are the uses of Levothyroxine Tablet:

• Used for treating hypothyroidism, a condition where the thyroid gland doesn't produce enough hormones.
• Used to manage an underactive thyroid, ensuring the body's metabolism functions properly.
• Used to relieve symptoms like fatigue, weight gain, and sensitivity to cold associated with low thyroid hormone levels.
• Used for replacement therapy in patients who have had thyroid surgery or radiation treatment.
• Used to treat congenital hypothyroidism in newborns to support healthy growth and development.
• Used to suppress thyroid-stimulating hormone (TSH) in specific thyroid cancers, as part of a treatment plan.
• Used to improve symptoms related to thyroid hormone deficiency, such as dry skin, hair loss, and depression.
• Used to support overall metabolic rate and energy levels in individuals with thyroid hormone deficiencies.

To be used as per doctor's prescription

In the case of an overdose of Levothyroxine Tablets, individuals may experience symptoms such as a rapid or irregular heartbeat, chest pain, confusion, and seizures. If an overdose is suspected, it is important to seek medical advice promptly. Treatment for overdose may involve managing symptoms and providing supportive care to ensure the individual's well-being. Prompt recognition and appropriate medical intervention are crucial to effectively address the potential health risks associated with Levothyroxine Tablet overdoses.

In the case of a missed dose of Levothyroxine Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may advise you to restart the medication at a lower dose to minimize any potential side effects. It is crucial to maintain a consistent medication routine for optimal results.

To take the Levothyroxine Tablet, swallow the tablet whole with a full glass of water, preferably on an empty stomach, at least 30 minutes to 1 hour before breakfast or as directed by your healthcare professional, and follow the dosage instructions provided by your doctor.

Following are the conditions or circumstances when Levothyroxine Tablet should not be taken:

• Allergy or hypersensitivity to Levothyroxine or any of the tablet's components.
• Patients with untreated or uncontrolled thyrotoxicosis (overactive thyroid).
• Individuals with recent or acute myocardial infarction (heart attack).
• Patients with adrenal insufficiency that is not adequately treated.
• In cases of thyrotoxicosis caused by nodular thyroid disease.
• Not to be used as a treatment for obesity or weight loss in patients with normal thyroid function.
• Contraindicated in patients with uncorrected adrenal insufficiency.
• Should not be the primary treatment for myxedema coma.

The side effects of Levothyroxine Tablet may include:

• Weight loss
• Increased appetite
• Diarrhea
• Vomiting
• Palpitations or increased heart rate
• Insomnia or difficulty sleeping
• Tremors or shaking
• Hair loss or thinning

Following are the precautions and warnings for Levothyroxine Tablet:

• It is crucial to take the medication exactly as prescribed by your healthcare provider. Do not adjust the dosage without medical advice.
• Regular blood tests may be required to monitor thyroid function and adjust the dosage accordingly.
• Inform your doctor about any medical conditions, especially heart disease, diabetes, or adrenal gland problems, as Levothyroxine may affect these conditions.
• Elderly individuals may be more sensitive to the effects of Levothyroxine, so close monitoring is essential.
• If you are undergoing radiation therapy for cancer, your Levothyroxine dose might need adjustment.
• This medication may cause osteoporosis, especially when used long-term. Regular bone density monitoring is recommended.
• If you experience chest pain, irregular heartbeat, or signs of an allergic reaction, seek immediate medical attention.

Following are the drug interactions for Levothyroxine Tablet:

• Anticoagulants like Warfarin may have reduced absorption when taken with Levothyroxine, requiring close monitoring of INR and potential Warfarin dose adjustment.
• Combined use with Sertraline may increase the risk of bleeding, and Sertraline can reduce Levothyroxine absorption.
• Calcium supplements and antacids containing aluminum, magnesium, or calcium can decrease the absorption of Levothyroxine if taken simultaneously.
• Taking Levothyroxine with Iron supplements or multivitamins containing Iron can decrease its absorption.
• Soy products, high-fiber foods, and some medications like Cholestyramine and Colestipol can interfere with Levothyroxine absorption.
• Sucralfate can reduce the absorption of Levothyroxine, so separate administration by several hours is recommended.
• Estrogens and oral contraceptives may increase the metabolic clearance of Levothyroxine, potentially requiring dosage adjustments.

Following are the food interactions for Levothyroxine Tablet:

• Avoid excessive consumption of foods rich in iodine, such as seaweed, kelp, or iodine-fortified foods, as it can affect thyroid function and reduce the effectiveness of the medication.
• Soy products like tofu, tempeh, and soy milk may interfere with Levothyroxine absorption, so it's best to separate soy intake and medication timing by several hours.
• High-fiber foods like bran cereals, whole wheat bread, and legumes can bind to Levothyroxine and reduce its absorption. Ensure a consistent gap between fiber intake and medication.
• Calcium-rich foods like dairy products, calcium-fortified juices, and supplements can also interfere with absorption. Take Levothyroxine on an empty stomach, and wait 4 hours before consuming calcium-rich items.
• Iron supplements and iron-rich foods like red meat, liver, and spinach can decrease Levothyroxine absorption. Separate iron intake and medication by a few hours.
• Coffee and caffeine-containing beverages may affect Levothyroxine absorption, especially when consumed in large amounts. Consider reducing caffeine intake or timing it away from medication.
• Avoid taking Levothyroxine with certain foods like walnuts, cottonseed meal, and high-fiber vegetables, as they can hinder the medication's absorption.

Levothyroxine tablets should be stored in a dry, cool place, preferably at room temperature, ensuring protection from light and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. Avoid storing the medication in the bathroom or near heat-emitting appliances, as high temperatures can impact its effectiveness. Proper disposal of unused or expired tablets is crucial; do not flush them down the toilet or pour them into drainage systems. Consult a pharmacist or healthcare professional for guidance on appropriate disposal methods to minimize environmental impact. Keep the medication out of children's reach to prevent accidental consumption, ensuring their safety.

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Following are the quick tips for Levothyroxine Tablet:

• Take the tablet on an empty stomach, preferably 30 minutes to 1 hour before breakfast, for better absorption.
• Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.
• Maintain a consistent daily routine; take the tablet at the same time each day.
• If you forget a dose, take it as soon as you remember, unless it's almost time for your next dose.
• Do not double the dose to make up for a missed one.
• Regularly monitor your thyroid function through blood tests as advised by your doctor.
• Inform your healthcare provider about all medications and supplements you're taking.