Timorex (0.5%) 5ml Eye Drops

Timolol is a non-selective beta-adrenergic blocker (beta-blocker). It works by blocking the action of certain chemicals, such as adrenaline, on beta-receptors in the eye. By doing so, Timolol decreases the production of aqueous humor (the fluid inside the eye) by the ciliary body. This reduction in fluid production lowers intraocular pressure (IOP), which is beneficial in the treatment of glaucoma and ocular hypertension. By controlling the pressure within the eye, Timolol helps to reduce the risk of optic nerve damage and vision loss associated with high intraocular pressure.

Timolol

Beta-adrenergic blocker (Beta-blocker)

Drop

The following are the uses of Timolol eye drops:

• Treatment of elevated intraocular pressure in patients with glaucoma (open-angle glaucoma).
• Management of ocular hypertension.
• Prevention of vision loss due to increased eye pressure.
• Treatment of conditions related to intraocular pressure in combination with other medications.
• Used as an adjunct in the management of certain types of glaucoma when monotherapy is insufficient.

Following are the doses of Timolol eye drops:

• The usual dose for glaucoma or ocular hypertension in adults is one drop in each affected eye once or twice daily, depending on the severity of the condition, as prescribed by a healthcare provider.
• If additional therapy is required, a combination with other ocular antihypertensive agents may be recommended.
• The dose may be adjusted based on individual response and the healthcare provider’s instructions.
• For pediatric patients, the dose is typically the same but should be carefully adjusted by the healthcare provider based on age and condition.

In the case of an overdose of Timolol eye drops, immediate medical attention should be sought. Although Timolol is primarily used topically for the eyes, an overdose may lead to symptoms such as slow heart rate (bradycardia), low blood pressure (hypotension), dizziness, shortness of breath, or even heart failure. If too much medication is accidentally applied, rinse the eyes with water or saline solution to remove any excess medication. Do not induce vomiting or take any other actions without consulting a healthcare provider. If severe symptoms such as chest pain, confusion, or difficulty breathing occur, seek medical attention immediately. Always follow the prescribed dosage and usage instructions to avoid overdose.

If you miss a dose of Timolol eye drops, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply two doses at the same time to make up for the missed dose, as this could increase the risk of side effects. Always follow the dosing instructions provided by your healthcare provider and consult them if you're unsure about how to proceed after missing a dose.

To use Timolol eye drops typically, Timolol is applied to the affected eye(s) once or twice a day, as prescribed. Tilt your head back, pull down your lower eyelid to create a small pocket, and apply the prescribed number of drops into the eye without letting the dropper touch your eye. After applying, gently close your eyes for a moment and press on the corner of your eye (near the nose) to prevent the medication from draining into the tear duct.

Following are the situations when Timolol eye drops should not be used:

• Should not be used in individuals with a known allergy to Timolol or any of its components.
• Contraindicated in patients with asthma, chronic obstructive pulmonary disease (COPD), or other severe respiratory conditions.
• Should not be used in patients with severe bradycardia (slow heart rate), heart block, or uncontrolled heart failure.
• Contraindicated in individuals with hypotension (low blood pressure).
• Should not be used in patients with a history of severe allergic reactions to beta-blockers.

The side effects of Timolol eye drops may include:

• Eye irritation
• Redness or stinging in the eyes
• Blurred vision
• Dry eyes
• Sensitivity to light
• Headache
• Dizziness
• Fatigue
• Shortness of breath or wheezing
• Bradycardia (slow heart rate)
• Low blood pressure

Following are the precautions and warnings for Timolol eye drops:

• Should not be used in individuals with a known allergy to Timolol or any of its ingredients.
• Contraindicated in patients with a history of bronchial asthma, severe chronic obstructive pulmonary disease (COPD), or other significant respiratory disorders.
• Should be used with caution in individuals with a history of heart disease, including bradycardia, heart block, or heart failure, as it may exacerbate these conditions.
• Caution is advised when using Timolol in individuals with diabetes, as it may mask the symptoms of hypoglycemia.
• Timolol may cause or worsen symptoms of depression or fatigue; patients should be monitored for these symptoms, particularly in elderly patients.
• Use with caution in patients with a history of thyroid disorders.
• Timolol should not be used during pregnancy or breastfeeding unless absolutely necessary, as it may harm the fetus or infant. Always consult a healthcare provider before use in such cases.

Following are the drug interactions for Timolol eye drops:

• Timolol may interact with systemic beta-blockers, leading to an increased risk of bradycardia, hypotension, and heart block.
• Concomitant use with calcium channel blockers (e.g., verapamil, diltiazem) may increase the risk of severe bradycardia and hypotension.
• Caution is advised when using Timolol with other medications that can lower blood pressure or affect heart rate, such as clonidine or digoxin.
• Timolol can enhance the hypotensive effects of other antihypertensive medications, including ACE inhibitors and diuretics.
• Use caution when combined with drugs that affect the liver, as this can alter the metabolism of Timolol.

Following are the food interactions for Timolol eye drops:

• There are no significant food interactions reported with Timolol eye drops.
• However, it is important to avoid excessive consumption of caffeine, as it may enhance the cardiovascular side effects of Timolol.
• Always consult your healthcare provider for personalized advice regarding diet and medication interactions.

Timolol eye drops should be stored at room temperature, away from moisture and direct sunlight. It is important to keep the bottle tightly closed when not in use to prevent contamination. Do not store the medication in the bathroom, as the humidity can affect the integrity of the drops. Keep the eye drop bottle out of reach of children to avoid accidental ingestion. If the solution changes color or becomes cloudy, or if it has been more than 28 days since the bottle was opened, it should be disposed of properly. For disposal, follow the instructions provided by your pharmacist or consult with your healthcare provider on the best way to safely discard the medication. Never flush it down the toilet or pour it down a drain.

Following are the quick tips for Timolol eye drops:

• Use Timolol eye drops exactly as prescribed by your healthcare provider for optimal results.
• Wash your hands thoroughly before applying the drops to prevent contamination.
• Tilt your head back, gently pull down your lower eyelid, and apply the prescribed number of drops into the eye without letting the dropper touch your eye.
• Close your eye gently after applying the drops and apply gentle pressure to the inner corner of the eye (near the nose) to prevent the medication from draining into your throat.
• Avoid wearing contact lenses while using Timolol unless directed otherwise by your healthcare provider.
• If you use other eye medications, wait at least 5 minutes between applying Timolol and any other eye drops.
• Do not stop using Timolol without consulting your healthcare provider, as stopping suddenly can cause your eye pressure to rise.

Timolol eye drops do not typically require routine laboratory screening or monitoring. However, in certain cases, the following considerations may be necessary:

• Regular eye exams to monitor the effectiveness of the treatment, ensuring intraocular pressure is adequately controlled.
• Routine blood pressure monitoring, as Timolol is a non-selective beta-blocker, which can affect systemic blood pressure.
• Periodic evaluation of heart rate and rhythm, especially for patients with pre-existing heart conditions, as Timolol can lower heart rate and may cause arrhythmias in some individuals.
• If you experience any symptoms such as dizziness, shortness of breath, or excessive fatigue, consult your healthcare provider for further evaluation.
• Patients with a history of asthma, chronic obstructive pulmonary disease (COPD), or other respiratory conditions should have periodic lung function assessments, as beta-blockers like Timolol may exacerbate respiratory issues.