Tobracin-D (0.3/0.1%) 5ml Eye Suspension

Tobramycin Eye Syrup/Suspension works by inhibiting bacterial protein synthesis. It specifically targets the 30S subunit of the bacterial ribosome, leading to disruption of mRNA translation. This mechanism prevents the bacteria from producing essential proteins necessary for their growth and replication. By binding to the ribosomal subunit, tobramycin interferes with the decoding process during protein synthesis, causing misreading of mRNA and subsequent production of faulty proteins, ultimately leading to bacterial cell death. This selective action makes tobramycin effective against a wide range of gram-negative bacteria commonly associated with eye infections.

Antibiotic eye drop

Drop

The following are the uses of Tobramycin Eye Syrup/Suspension:

• Used for treating bacterial eye infections such as conjunctivitis and blepharitis.
• Used for preventing and controlling post-operative eye infections.
• Used for reducing inflammation and preventing eye damage in conditions like keratitis.
• Used for managing chronic eye infections that require long-term treatment.
• Used for treating eye infections in contact lens wearers.
• Used for improving eye comfort and reducing discharge.
• Used for preventing eye infections in at-risk individuals.
• Used for adjunct therapy with other eye medications.

In the case of an overdose of Tobramycin Eye Syrup/Suspension, it is important to remain calm and seek medical advice promptly. While not typically life-threatening, an overdose may cause increased eye irritation, redness, and potential discomfort. The severity of symptoms can vary depending on the amount ingested. It is recommended to contact a healthcare professional or poison control center for guidance, as they can provide specific instructions for managing the situation effectively.

In the case of a missed dose of Tobramycin Eye Syrup/Suspension, it is important to administer the medication as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to adjust your dosing schedule and ensure the medication's effectiveness.

To use Tobramycin Eye Syrup/Suspension, gently shake the bottle, tilt your head back, instill the prescribed number of drops into the affected eye(s), and follow your healthcare professional's instructions for administration and frequency.

Following are the conditions or situations when Tobramycin Eye Syrup/Suspension should not be used:

• Must not be used if you have a known allergy or hypersensitivity to Tobramycin or any other aminoglycoside antibiotics.
• Avoid using it if you have a viral or fungal infection in the eye(s), as Tobramycin is specifically effective against bacterial infections.
• Not recommended for individuals with a history of sensitivity or severe reactions to other eye drops or similar medications.
• Do not use Tobramycin Eye Suspension if you have a perforated eardrum, as it can lead to inner ear problems.
• Should not be used if you have a history of myasthenia gravis, as it may worsen muscle weakness.
• Avoid using it if you have a condition where the eye surface is damaged or compromised, such as corneal ulcers or herpes simplex keratitis.
• Not suitable for individuals with a history of hearing problems or balance disorders.

The side effects of Tobramycin Eye Syrup/Suspension may include:

• Eye irritation or redness
• Itching or stinging sensation in the eyes
• Watery eyes
• Blurred vision
• Eye discharge or crusting
• Increased sensitivity to light
• Swelling or inflammation of the eyelids

Following are the precautions and warnings for Tobramycin Eye Syrup/Suspension:

• This medication is for external use only and should be administered directly to the eye(s) as directed. Do not swallow or inject.
• Wash your hands thoroughly before and after using the eye drops to avoid contamination.
• Contact lenses should be removed before applying the eye drops and can be reinserted after 15 minutes.
• Do not touch the dropper tip to any surface as it may contaminate the solution.
• If you are using other eye medications, apply them at least 5-10 minutes apart to prevent washout.
• Inform your doctor if you have or have ever had a history of kidney disease, as tobramycin can affect kidney function.
• Discontinue use and seek medical attention if you experience any signs of an allergic reaction, such as itching, swelling, or difficulty breathing.
• Prolonged use of tobramycin may result in the growth of resistant bacteria; use the medication only as prescribed and complete the full course of treatment.

Following are the drug interactions for Tobramycin Eye Syrup/Suspension:

• When used with other aminoglycoside antibiotics, the risk of ototoxicity and nephrotoxicity may increase.
• Concomitant use with potent diuretics, such as furosemide, can enhance the ototoxicity potential.
• Tobramycin may interact with other ophthalmic medications, such as beta-blocker eye drops, leading to reduced effectiveness of either medication.
• Neuromuscular blocking agents can have their effects potentiated by tobramycin, possibly causing prolonged respiratory depression.
• Drugs that impair kidney function may increase serum levels of tobramycin, increasing the risk of toxicity.
• Antibacterial activity may be reduced when combined with other medications that affect the normal flora of the eye.
• Concurrent use with other nephrotoxic drugs should be avoided to minimize kidney damage.

Following are the food interactions for Tobramycin Eye Syrup/Suspension:

• Tobramycin eye medication is for external use only, so there are no direct food interactions.
• It is generally safe to consume food and drinks as usual while using this eye medication.
• No specific dietary restrictions are associated with Tobramycin eye drops/ointment.
• Avoid touching the dropper or tube tip to any surface, including food items, to prevent contamination.
• Wash your hands before and after using the eye medication to maintain hygiene.
• If you experience any eye irritation or discomfort after using the medication, consult your doctor or pharmacist before consuming any specific food or drink.
• Some foods with high salt content or preservatives might cause mild irritation if your eyes are sensitive, but this is not a direct interaction.
• Overall, Tobramycin eye medication can be used without worrying about food or drink restrictions.

Tobramycin Eye Syrup/Suspension should be stored with caution to maintain its effectiveness and safety. Keep the medication in a cool, dry place, preferably at room temperature, ensuring it is protected from direct sunlight and moisture. It is crucial to store it in its original container, tightly sealed, to prevent contamination. Avoid extreme temperatures by not placing it in the refrigerator, freezer, or near heat sources. Always refer to the packaging for the expiration date, and never use the medication beyond this date. When disposing of the eye syrup, do not flush it down the toilet or pour it into drainage systems. Instead, consult a pharmacist or healthcare professional for appropriate disposal methods to ensure environmental safety. Keep the medication away from children to prevent accidental contact or ingestion.

Following are the quick tips for Tobramycin Eye Syrup/Suspension:

• Wash your hands thoroughly before administering the eye drops or ointment to maintain hygiene.
• Tilt your head back, gently pull down your lower eyelid, and apply the medication without touching the dropper/tube to any surface.
• Close your eyes gently after instilling the drops and apply light pressure to the tear duct (inner corner of the eye) to minimize drainage.
• If using other eye medications, wait at least 5-10 minutes before applying the next one to prevent washout.
• Store the eye drops/ointment at room temperature, away from direct sunlight and moisture.
• Do not wear contact lenses while using this medication unless your doctor advises otherwise.
• Inform your doctor if you have any allergies or experience persistent eye irritation during treatment.