TOP GEL MCA 30GM

The mechanism of action of Neomycin and Fluocinonide Gel involves the combination of two active ingredients. Neomycin, an aminoglycoside antibiotic, binds to bacterial ribosomes, disrupting protein synthesis and leading to bacterial cell death, particularly targeting gram-negative bacteria. Fluocinonide, a synthetic corticosteroid, exerts its anti-inflammatory effects by binding to cytoplasmic glucocorticoid receptors, inhibiting the production of pro-inflammatory mediators, and suppressing immune responses. Together, Neomycin and Fluocinonide work synergistically to combat bacterial infections and reduce inflammation, making it effective for the topical treatment of various skin conditions.

Antibiotic, Corticosteroid.

Gel

The following are the uses of Neomycin, Fluocinonide Gel:

• Used for treating skin infections and reducing inflammation
• Used for alleviating symptoms of eczema and dermatitis
• Used for managing skin redness and irritation
• Used for promoting healing in minor skin injuries
• Used for reducing itching and discomfort in affected areas
• Used for treating insect bites and mild allergic reactions on the skin
• Used for providing relief from mild to moderate psoriasis symptoms
• Used for supporting the healing process after minor skin surgeries

In the case of an overdose of Neomycin and Fluocinonide Gel, it is important to remain calm and take appropriate actions. If ingested, do not induce vomiting. Contact a healthcare professional or a poison control center immediately for guidance. They will provide specific instructions based on the individual's condition and the amount of medication involved. Quick action can help mitigate potential adverse effects and ensure the best possible outcome.

In the case of a missed dose of Neomycin, apply the gel as soon as you remember, but if it's almost time for your next dose, skip the missed application and continue with your regular schedule. For Fluocinonide Gel, if you miss a dose, apply it as soon as you notice the missed application, but avoid applying a double dose to make up for the missed one. It's important not to overuse these medications, and if you have any concerns or frequently miss doses, consult your healthcare provider for guidance.

To apply Neomycin and Fluocinonide Gel, clean and dry the affected skin area, then gently apply a thin layer of the gel to the skin, spreading it evenly, usually two to three times a day or as directed by your doctor.

Following are the conditions/situations when Neomycin, Fluocinonide Gel should not be used:

• Do not use if you are allergic to any of the ingredients in the gel, including neomycin or fluocinonide.
• Avoid using the gel if you have a skin infection or open wounds at the site of application.
• Should not be used in individuals with a history of hypersensitivity or severe reactions to similar corticosteroids.
• Not suitable for individuals with skin conditions like rosacea, acne, or perioral dermatitis.
• Do not use on skin that is irritated, broken, or sunburned.
• Avoid contact with eyes, mouth, and nose while applying the gel.
• Not recommended for long-term use, especially on large areas of the body.
• Do not use on children under 2 years of age without medical advice.
• Contraindicated in individuals with certain skin disorders, such as impetigo, viral diseases, or fungal infections.

The side effects of Neomycin, Fluocinonide Gel may include:

• Skin irritation or redness at the application site
• Itching or burning sensation
• Dryness or peeling of the skin
• Allergic reactions (such as rash, hives, or difficulty breathing)
• Thinning of the skin
• Stretch marks
• Acne or folliculitis

Following are the precautions and warnings:

• Neomycin, Fluocinonide Gel should not be used if you are allergic to any of its ingredients. Avoid use if you have a known hypersensitivity to neomycin, fluocinonide, or other similar medications.
• This gel is for external use only and should not be applied to the eyes, mouth, or open wounds.
• Do not use this medication for extended periods without medical supervision, as prolonged use may lead to skin thinning, stretch marks, or other skin damage.
• Avoid using occlusive dressings or bandages over the treated area unless directed by a healthcare professional.
• If you are pregnant or breastfeeding, consult your doctor before using this gel, as the risks and benefits should be carefully considered.
• Keep the gel away from direct sunlight and store it in a cool, dry place, as directed on the packaging.
• Do not use Neomycin, Fluocinonide Gel on large areas of the body or on skin conditions that cover a significant portion of the body without medical advice.
• Discontinue use and seek medical attention if you experience severe irritation, redness, or any signs of an allergic reaction.

Following are the drug interactions for Neomycin, Fluocinonide Gel:

• Neomycin may reduce the absorption of oral medications like vitamin B complex and fat-soluble vitamins (A, D, E, K) when taken together.
• Fluocinonide can increase the risk of systemic steroid side effects when used with oral corticosteroids.
• Topical use with other corticosteroids may enhance local and systemic side effects.
• Neomycin can interact with drugs that affect kidney function, such as gentamicin or cisplatin, increasing the risk of kidney damage.
• It may decrease the effectiveness of live bacterial vaccines (e.g., typhoid vaccine) and live attenuated viral vaccines (e.g., measles, mumps, rubella).
• The gel may reduce the efficacy of topical anti-infective agents if applied together.
• Caution is advised when using with other topical medications, as it may increase skin irritation.

Following are the food interactions for Neomycin, Fluocinonide Gel:

• Avoid consuming large amounts of high-potassium foods like bananas, oranges, and tomatoes, as Neomycin can affect potassium levels.
• Limit or avoid consuming dairy products and calcium-rich foods while using Fluocinonide, as calcium can interact with the medication's absorption.
• Grapefruit and grapefruit juice should be avoided as they may interfere with the metabolism of certain drugs, potentially affecting Fluocinonide's effectiveness.
• Alcoholic beverages might increase skin irritation and dryness when used with Fluocinonide, so it's best to minimize or avoid alcohol consumption.
• Caffeine-rich foods and beverages may enhance skin sensitivity, so consider reducing coffee, tea, and chocolate intake during treatment.
• Avoid spicy foods, as they can temporarily increase skin blood flow and potentially exacerbate skin conditions when using Fluocinonide.
• Always stay well-hydrated by drinking plenty of water to support overall skin health during medication use.

Neomycin, Fluocinonide Gel should be stored in a cool and dry place, preferably at room temperature (around 25°C). Keep the tube tightly sealed and protected from direct exposure to sunlight or moisture to maintain its integrity. Always check the expiration date, and dispose of the gel properly by returning it to a pharmacy or healthcare facility for safe disposal, ensuring it is not discarded with regular household waste. Do not pour the gel down the drain or flush it, as it can have environmental implications. Keep the medication out of sight and reach of children and pets to prevent accidental exposure or ingestion. It is important to follow these storage and disposal guidelines to maintain the effectiveness and safety of the medication.

Following are the quick tips for Neomycin and Fluocinonide Gel:

• Wash your hands before and after applying the gel to maintain hygiene.
• Clean and dry the affected area before applying the gel.
• Apply a thin layer of Neomycin as directed, usually 3-4 times daily.
• Gently rub Fluocinonide Gel into the skin until it disappears, typically 2-3 times daily as prescribed.
• Avoid applying the gel on broken or infected skin.
• Do not cover the treated area with bandages or tight clothing to allow the skin to breathe.
• Store the gel at room temperature, away from heat and direct sunlight.