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Labetalol HCl
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Product Information
Labetalol HCl injection is a unique beta-blocker that exhibits both selective alpha-adrenergic receptor blocking activity and non-selective beta-adrenergic receptor blocking activity. It acts by competitively blocking the binding of catecholamines, such as adrenaline and noradrenaline, to these receptors. Specifically, labetalol binds to beta1-adrenergic receptors in the heart, reducing heart rate and cardiac contractility, which results in decreased cardiac output and blood pressure. Additionally, its alpha-blocking effect leads to vasodilation by inhibiting the constrictive influence of adrenaline and noradrenaline on alpha-adrenergic receptors in blood vessels, further contributing to the reduction of blood pressure. This dual mechanism of action makes labetalol particularly effective in the rapid control of hypertension and the management of hypertensive emergencies.
Labetalol HCl
Beta-blocker.
Injection
The following are the uses of Labetalol HCl Injection:
In the case of an overdose of Labetalol HCl Injection, prompt medical attention is necessary. Symptoms may include severe hypotension, bradycardia, dizziness, and even loss of consciousness. Treatment should focus on managing these symptoms and maintaining vital signs. This may involve discontinuing the medication, providing cardiovascular support, and monitoring vital signs until the patient stabilizes. It is crucial to seek medical assistance promptly to ensure appropriate management of the overdose.
In the case of a missed dose of Labetalol HCl Injection, it is important to administer the medication as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Avoid doubling the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare professional for guidance on how to safely resume the medication. Always store the medication properly and handle it with care to ensure its effectiveness.
To administer Labetalol HCl Injection, ensure the solution is clear and free of particles, then using a sterile syringe, draw the prescribed dose, and inject it slowly into the intravenous line or as directed by your healthcare professional, following the recommended dosage and administration guidelines provided.
Following are the conditions/situations when Labetalol HCl Injection should not be administered:
The side effects of Labetalol HCl Injection may include:
Following are the precautions and warnings for Labetalol HCl Injection:
Following are the drug interactions for Labetalol HCl Injection:
Following are the food interactions to be aware of when taking Labetalol HCl Injection:
Labetalol HCl Injection should be stored in a controlled environment, preferably in a cool and dry place, away from direct sunlight and moisture. The recommended storage temperature is between 20°C and 25°C (68°F to 77°F). It is crucial to keep the injection in its original packaging, tightly sealed, to maintain its sterility and integrity. Do not use the injection if the seal is broken or if there are any signs of tampering. When disposing of Labetalol HCl Injection, follow local regulations and guidelines for pharmaceutical waste disposal. Do not dispose of it in regular household trash or pour it down the drain. Contact your healthcare provider or pharmacist for guidance on proper disposal methods to ensure environmental safety. Keep this medication securely stored and out of the reach of children and pets.
Following are the quick tips for Labetalol HCl Injection:
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