Transamin (250mg) 100 Capsules

Tranexamic acid (TXA) is a medication that functions as an antifibrinoloytic, meaning it helps stop bleeding by preventing the breakdown of blood clots. It does this by blocking the activation of plasminogen, an enzyme that breaks down blood clots, thereby helping to stabilize clots and reduce bleeding. TXA is particularly important in situations where excessive bleeding is a risk. Its mechanism of action relies on its ability to interact with the lysine binding sites of plasminogen, specifically blocking the active site of plasminogen and thus preventing its conversion to plasmin, an enzyme that breaks down fibrinogen and fibrin strands of a blood clot. By inhibiting plasminogen activation, TXA helps to maintain fibrin clots intact, which is particularly important in situations where effective clotting and the prevention of bleeding is necessary.

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Antifibrinolytic

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Capsule

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Unveiling its multifaceted uses and transformative applications as follows:

• Promote clot formation
• Treatment of bleeding episodes & peri-operative bleeding in Hemophilia A & B
• Managing Bleeding in Patients on Oral Contraceptives
• For surgery in patients with congenital FVII deficiency
• In patients with Acute Traumatic Injury
• Bleeding episodes & peri-operative bleeding in Von Willebrand disease.

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Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For heavy menstrual bleeding (menorrhagia)- Take 1 tablet of Tranexamic Acid 250mg 3 times a day, ideally at mealtimes to reduce stomach upset.
• For thrombocytopenia (low platelet count)- The dose will depend on the severity of your condition and your doctor's assessment. The typical starting dose is 1g (1,000mg) daily, divided into 3 smaller doses of 333mg taken at mealtimes. Your doctor may adjust this dose depending on your response and tolerance.
• For dental surgery- The recommended dose is 1 tablet of Tranexamic Acid 250mg taken 2 hours before surgery, followed by another tablet after an hour, and then a third tablet 2 hours after the surgery. This regimen helps reduce the risk of bleeding during and after the procedure.

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Tranexamic acid is a medication that, when taken in appropriate doses as advised by a medical professional, can help treat certain medical conditions. However, if too much of this medication is taken, it is considered an overdose and can lead to various symptoms such as constipation, nausea, vomiting, thirst, dizziness, and headache. In more severe cases, low blood pressure, wheezing, and changes in mental status may occur. It is crucial to understand that there is no specific antidote to counteract the effects of tranexamic acid overdose. However, it is important to monitor for worsening symptoms or complications and consider dialysis if there is an extensive overdose. If you suspect someone has experienced an overdose, it is imperative to seek medical attention as soon as possible. If medical attention is not immediately available, basic life support (BLS) techniques may be required, which involve checking if the person is breathing normally, assessing their airway for any blockages, and providing CPR if needed. Attendees should monitor the symptoms and if they worsen and hospitalization may be required for severe symptoms.

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If you miss a dose of tranexamic acid, it is important to take it as soon as possible unless it is almost time for the next dose. If you miss a dose by a small margin, skip the missed dose entirely and continue the regular schedule. Do not attempt to make up for a missed dose by taking more medicine, as this can be harmful. If you have missed several doses or are unsure about the correct dosing schedule, it is best to contact your doctor for advice on how to move forward. It is also important to consult your doctor immediately if you experience any unusual symptoms after missing a dose, as they may indicate a problem that requires medical attention.

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Tranexamic Acid is a medication that is prescribed to help reduce or prevent bleeding during dental or surgery procedures. The specific directions for using Tranexamic Acid depend on the individual recommendations of the doctor or dentist and the product being used. It is important to follow the instructions provided by the healthcare provider. This medication comes with a guide that explains the proper dosage, schedule, and potential side effects. Before taking this medication, it is important to read the provided guide thoroughly. If there are any questions, consult a doctor or pharmacist. The doctor will provide specific instructions on the dosage and schedule depending on the form of the medication and the type of procedure. Paying close attention to the timing of the medication is vital to take it as directed. Tranexamic Acid is typically used for a short period, mainly until the procedure and recovery period are finished. It is important to continue taking it until the course of treatment is complete, even if you feel well and your symptoms have improved. If a dose is missed, it is essential to contact the healthcare provider for instructions on how to proceed.

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Discerning instances where this medication may not be appropriate:

• You are allergic to tranexamic acid or any of the other ingredients in the specific formulation you are considering.
• You have severe blood clots in your veins or arteries (e.g. deep vein thrombosis or pulmonary embolism).
• You have recently had a stroke or developed certain types of seizures.
• You have severe liver disease or severe kidney disease.
• You have a serious infection or are currently being treated with antibiotics.
• You are pregnant or planning to become pregnant.
• You are breastfeeding.
• You have a upcoming surgery or dental procedure in the next few days.
• You have any condition or disease that can increase your risk of bleeding problems, such as hemophilia or low platelet counts.
• You are taking any medications that can increase the risk of bleeding, such as blood thinners (like warfarin), anti-platelet drugs (like aspirin or clopidogrel), or non-steroidal anti-inflammatory drugs (like ibuprofen or naproxen).

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Unraveling the side effects lurking behind this medications are as follows:

• Local skin reactions at the injection site
• Thrombosis
• Hematuria
• Hepatitis
• Transaminase elevation
• Headache
• Insomnia
• Vertigo
• Anxiety
• Impaired fertility
• Interference with labor and delivery
• Cataracts
• Retinopathy

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Here are some important precautions and warnings that patients should be aware of:

• Patients with massive hematuria from the upper urinary tract, uncorrected cardiovascular or cerebrovascular disease, or subarachnoid hemorrhage should exercise caution.
• Women with irregular menstrual cycles should avoid use; it is not recommended prior to menarche or post-menopause.
• The medication is not recommended for use in patients with acute promyelocytic leukemia who are taking oral tretinoin.
• Caution is advised for those with mild to moderate renal impairment.
• Special considerations are required during pregnancy and lactation.

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Drug interactions with tranexamic acid include:

• Anticoagulants (e.g., warfarin) (may increase the risk of thromboembolic events)
• Estrogens (e.g., oral contraceptives) (may increase the risk of thromboembolic events)
• Aminocaproic acid (may enhance antifibrinolytic effects)
• Fibrinolytic agents (e.g., tissue plasminogen activator) (may reduce the efficacy of fibrinolysis)

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Tranexamic acid should be stored at room temperature, typically between 20°C to 25°C, and protected from moisture and light.

For disposal, do not dispose of tranexamic acid in household trash unless specifically instructed to do so. Avoid flushing it down the toilet, as this can harm the environment. Follow local regulations for medication disposal, including utilizing drug take-back programs if available. 

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