Trazolam (100mg) 30 Tablets

Trazodone 100mg tablets primarily exert their therapeutic effects through selective inhibition of serotonin reuptake in the brain. This mechanism of action is attributed to trazodone's ability to block the serotonin transporter (SERT), leading to increased serotonin levels in the synaptic cleft. By enhancing serotonin neurotransmission, trazodone can modulate mood, alleviate symptoms of depression, and improve overall emotional well-being. Additionally, trazodone's affinity for certain serotonin receptor subtypes, particularly 5-HT1A receptors, may contribute to its overall antidepressant and anxiolytic properties. The selective modulation of serotonin levels is believed to underlie the efficacy of trazodone in treating major depressive disorder and various other psychiatric conditions.

Antidepressant

Tablet

The following are the uses of Trazodone 100mg Tablet:

• Used for treating depression, providing relief from symptoms like persistent sadness and hopelessness.
• Used for managing anxiety disorders, helping to control excessive worry and panic attacks.
• Used to promote better sleep by treating insomnia, allowing individuals to fall asleep more easily.
• Used for alleviating symptoms of pain, especially when associated with conditions like fibromyalgia.
• Used for migraine management, reducing the frequency and severity of migraine headaches.
• Used for controlling aggression and impulsive behavior, particularly in individuals with behavioral disorders.
• Used as an adjunctive treatment for alcohol withdrawal, aiding in managing withdrawal symptoms.

In the case of an overdose of Trazodone 100mg Tablets, it is important to recognize the potential severity of this situation. Symptoms may include drowsiness, dizziness, and in more serious cases, a rapid heart rate, confusion, and even seizures. If an overdose is suspected, immediate action should be taken. Contact a healthcare professional or a poison control center for guidance on the next steps, which may include seeking emergency medical assistance to ensure proper treatment and support.

In the case of a missed dose of Trazodone 100mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss several doses, contact your healthcare provider for advice on how to get back on track with your medication regimen. It is generally recommended to take the medication at the same time each day to maintain consistent levels in your system.

To take Trazodone 100mg Tablets, swallow the tablet whole with a full glass of water, preferably at bedtime or as directed by your healthcare professional, ensuring you follow the prescribed dosage and duration as instructed.

Following are the conditions/situations when Trazodone 100mg Tablet should not be taken:

• Must not be consumed if you are allergic to Trazodone or similar medications.
• Not suitable for individuals with a history of heart attack or heart disease.
• Avoid if you have recently had a stroke.
• Do not take if you are currently experiencing unstable seizures.
• Contraindicated for individuals with liver or kidney failure.
• Should not be taken if you are currently taking Monoamine Oxidase Inhibitors (MAOIs).
• Avoid if you have a personal or family history of Long QT Syndrome.

The side effects of Trazodone 100mg Tablet may include:

• Drowsiness or sedation
• Dry mouth
• Nausea and vomiting
• Constipation
• Dizziness
• Blurred vision
• Increased heart rate
• Confusion, especially in older adults
• Muscle pain or weakness

Following are the precautions and warnings for Trazodone 100mg Tablet:

• Not suitable for individuals with a known allergy to Trazodone or related antidepressants.
• Patients with a history of heart problems, especially cardiac arrhythmias, should use with caution and under medical supervision.
• May cause dizziness or drowsiness; patients should avoid driving, operating heavy machinery, or engaging in activities requiring mental alertness until they know how the medication affects them.
• Elderly patients may be more sensitive to the side effects; regular monitoring is recommended.
• Individuals with a history of seizures or epilepsy should use with caution as it may lower the seizure threshold.
• Not recommended for use during pregnancy or breastfeeding unless the potential benefits outweigh the risks, as determined by a healthcare professional.
• Trazodone can interact with other medications; inform your doctor about all medications you are taking, especially antidepressants, opioids, or blood thinners.

Following are the drug interactions for Trazodone 100mg Tablet:

• Alcohol and other central nervous system (CNS) depressants (e.g., benzodiazepines, opioids) can increase the sedative effects of Trazodone, leading to enhanced drowsiness and impaired motor skills.
• The risk of serotonin syndrome increases when combined with other serotonergic medications like selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), or monoamine oxidase inhibitors (MAOIs).
• Trazodone may enhance the effects of anticoagulants, such as warfarin, potentially increasing the risk of bleeding.
• The blood pressure-lowering effect of antihypertensive medications may be potentiated by Trazodone, leading to possible orthostatic hypotension.
• Trazodone can elevate the blood levels of certain anticonvulsants, increasing the risk of side effects.
• When taken with other medications that are also metabolized by the liver's CYP450 enzymes, Trazodone may affect their metabolism, resulting in either increased or decreased drug levels.
• The heart rhythm-regulating effects of antiarrhythmic medications may be altered by Trazodone, requiring close monitoring.

Following are the food interactions for Trazodone 100mg Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can increase the levels of Trazodone in the blood, potentially leading to increased side effects.
• Alcohol is not recommended with Trazodone as it can enhance the sedative effects, causing excessive drowsiness and dizziness.
• Avoid high-fat meals as they may slow down the absorption of Trazodone, delaying its therapeutic effect.
• Caffeine intake should be monitored as it can interact with Trazodone, potentially causing increased anxiety or insomnia.
• Avoid eating large quantities of tyramine-rich foods like aged cheeses, cured meats, and certain types of beer, as Trazodone may interact with tyramine, leading to a spike in blood pressure.
• Consuming foods high in salt and preservatives may reduce the effectiveness of Trazodone and should be limited.
• Always take Trazodone with food to reduce the risk of stomach upset and nausea.
• Consult your healthcare provider for personalized dietary advice while taking Trazodone.

Trazodone 100mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet, at room temperature (around 25°C) and away from direct sunlight, moisture, and heat. It is crucial to keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to external elements. Always check the expiration date before taking any medication, and if the tablets have expired, do not use them and dispose of them properly. For safe disposal, do not throw the medication in the trash or flush it down the toilet; instead, consult your pharmacist or local waste management guidelines for specific instructions on how to dispose of pharmaceutical waste responsibly, ensuring that it does not harm the environment or pose a risk to others. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Trazodone 100mg Tablet:

• Consult your doctor before starting this medication, especially if you have a history of heart disease, liver/kidney issues, or breathing problems.
• Take the tablet as directed by your doctor, usually once or twice daily.
• You can take it with or without food, but be consistent with your choice.
• Avoid alcohol as it may increase the risk of side effects.
• Do not stop taking the medication suddenly without consulting your doctor.
• Store the tablets at room temperature, away from light and moisture.
• Inform your doctor about all medications you're taking to avoid potential interactions.
• Stay alert for any unusual changes in mood or behavior and report them promptly.