TRITANRIX HB INJ 5ML

TRITANRIX HB INJ 5ML

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  • Manufacturer GSK
  • Generic Name Diphtheria Toxoids, Hepatitis B Vaccine [

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Diphtheria Toxoid and Hepatitis B Vaccine is a combination vaccine that works by stimulating the body's immune system to produce antibodies against both diphtheria and hepatitis B. The diphtheria toxoid component is an inactivated form of the diphtheria toxin, which triggers the production of antibodies that neutralize the toxin's effects. This prevents the toxin from causing damage to cells, especially in the respiratory tract, where diphtheria can lead to severe respiratory complications. The hepatitis B component of the vaccine contains non-infectious viral antigens that mimic the hepatitis B virus. When administered, these antigens stimulate the immune system to generate a protective response, producing antibodies that specifically target the hepatitis B surface antigen. This immune response helps prevent infection and disease caused by the hepatitis B virus.

  • Ingredients

    Diphtheria Toxoids, Hepatitis B Vaccine [
  • Drug Class

    Hepatitis B vaccine, Diphtheria toxoid

  • Dosage Form

    Injection

  • Uses

    The following are the uses of Diphtheria Toxoids 30, Hepatitis B Vaccine [ 10 mcg/0.5ml] Injection:

    • Used for preventing Diphtheria, a severe bacterial infection that can affect the throat and respiratory system.
    • Used for Hepatitis B immunization, offering protection against this viral infection that impacts the liver.
    • Provides immunity against Diphtheria and Hepatitis B, reducing the risk of severe complications.
    • Effective in individuals with compromised immune systems, such as those with HIV or undergoing chemotherapy.
    • Recommended for travelers to regions with high Diphtheria and Hepatitis B prevalence.
    • Used for post-exposure prophylaxis after potential exposure to Hepatitis B.
    • Ensures ongoing protection through booster doses for long-term immunity.
  • In case of Overdose

    In the case of an overdose of Diphtheria Toxoids 30 and Hepatitis B Vaccine, seek medical advice promptly. Overdose symptoms may include pain, swelling, or redness at the injection site. Additionally, an overdose may lead to an increased risk of adverse reactions associated with the vaccine, such as fever, fatigue, or gastrointestinal issues. Prompt consultation with a healthcare professional is necessary to manage any potential side effects and ensure appropriate medical care.

  • Missed Dose

    In the case of a missed dose of Diphtheria Toxoids 30, it is recommended to consult your healthcare provider for advice. They will likely suggest scheduling the next dose as soon as possible to maintain protection. For the Hepatitis B Vaccine, if a dose is missed, it is best to administer the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose to make up for a missed one.

  • How To Use

    To administer the Diphtheria Toxoids 30, Hepatitis B Vaccine [ 10 mcg/0.5ml] Injection, gently shake the pre-filled syringe or vial to ensure a uniform mixture, then using a sterile needle and syringe, draw the prescribed dose, inject it intramuscularly into the deltoid muscle, and follow the recommended immunization schedule provided by your healthcare provider.

  • When Not to Use

    Following are the conditions/situations when Diphtheria Toxoids 30 and Hepatitis B Vaccine should not be administered:

    • Should not be used in individuals with a history of severe allergic reactions to any component of the vaccine, including yeast, formaldehyde, or any other ingredient.
    • Contraindicated in individuals who have shown signs of hypersensitivity or anaphylaxis after previous administration of the vaccine.
    • Not recommended for individuals with a severe allergy to latex, as some vaccine vials may contain latex in the packaging.
    • Should not be administered to individuals with a known severe allergy to other vaccines or medications.
    • Not suitable for individuals with a moderate or severe illness at the time of vaccination.
    • Should not be used in individuals with a history of neurological disorders or seizures immediately following a previous dose of a vaccine containing similar components.
    • Contraindicated during an active untreated tuberculosis infection.
  • Side Effects

    The potential side effects of Diphtheria Toxoids 30, Hepatitis B Vaccine Injection may include:

    • Pain, redness, or swelling at the injection site
    • Mild fever
    • Fatigue
    • Headache
    • Muscle or joint pain
    • Nausea or vomiting
    • Loss of appetite
    • Allergic reactions (rare) such as rash, itching, or difficulty breathing
  • Precautions & Warnings

    Following are the precautions and warnings for Diphtheria Toxoids 30, Hepatitis B Vaccine [10 mcg/0.5ml] Injection:

    • This vaccine is not meant to treat active infections; it is a preventive measure. Do not delay seeking medical advice if you suspect an active infection.
    • Inform your healthcare provider if you have any bleeding disorders or if you are currently on blood-thinning medications.
    • If you have a history of severe allergic reactions to any vaccine or medication, inform your doctor before administration.
    • The vaccine should be used with caution in individuals with a history of neurological disorders, as it may rarely cause neurological complications.
    • Some mild side effects like fever, pain at the injection site, and fatigue are common but consult a doctor if they persist or worsen.
    • Ensure that you complete the entire vaccination schedule as prescribed by your healthcare provider for optimal protection.
    • Pregnant and breastfeeding women should only receive this vaccine if clearly needed, and the potential benefits outweigh the risks.
  • Drug Interactions

    Following are the drug interactions for Diphtheria Toxoids 30, Hepatitis B Vaccine:

    • The concurrent use of immunosuppressant drugs or other vaccines may interfere with the immune response to the Hepatitis B Vaccine.
    • Live vaccines should be avoided for at least 3 months after receiving Hepatitis B Vaccine to prevent potential interference.
    • Antibiotics like ampicillin and other beta-lactams can potentially reduce the effectiveness of Diphtheria Toxoids.
    • Corticosteroids and other immunosuppressive therapies may decrease the immune response to Diphtheria Toxoids.
    • Concomitant administration with other vaccines should be done at different injection sites and with separate syringes to avoid mixing.
    • Blood thinners such as warfarin may have an increased risk of bleeding at the injection site when combined with this vaccine.
    • Certain medications that affect the immune system, like immunomodulators, might influence the efficacy of the vaccine.
  • Food Interactions

    Following are the food interactions for Diphtheria Toxoids 30 and Hepatitis B Vaccine:

    • No specific food interactions are known for Diphtheria Toxoids. However, maintaining a healthy and balanced diet is essential to support the immune system's response to vaccines.
    • Avoid consuming alcohol before or after Hepatitis B Vaccine administration, as it may interfere with the immune response and reduce the vaccine's effectiveness.
    • Fatty foods and high-fat meals may not directly interact with the vaccine, but a healthy diet with moderate fat content is recommended to support overall health.
    • Grapefruit and grapefruit juice should be consumed with caution, as they can affect the liver enzymes, although this interaction is less likely with the vaccine.
    • Avoid spicy foods if you experience injection site pain or discomfort after vaccination, as spicy foods may irritate the injection site.
    • Stay hydrated by drinking plenty of water to support your body's immune response and overall well-being.
    • There is no known interaction between specific foods and the vaccine's absorption or effectiveness, but maintaining a nutritious diet is beneficial.
    • Always follow the healthcare provider's instructions and guidelines for vaccination and overall health.
  • Storage/Disposal

    Diphtheria Toxoids 30 and Hepatitis B Vaccine should be stored in a cool, dry place between 2°C and 8°C (36°F and 46°F) in their original packaging to maintain potency and sterility. Avoid freezing the vaccines as it may render them ineffective. Once opened, the vials should be used immediately, and any unused portions should be discarded. Proper disposal of unused or expired vaccines is crucial; do not throw them into the regular trash. Contact local waste management authorities or healthcare providers for guidance on safe disposal methods to minimize environmental impact. Always follow storage and disposal instructions provided by the manufacturer to ensure the integrity and safety of the vaccines.

  • Quick Tips, if any

    Following are the quick tips for Diphtheria Toxoids 30 and Hepatitis B Vaccine:

    • Store the vaccine between 2°C and 8°C, protecting it from freezing.
    • Administer the vaccine intramuscularly as directed by a healthcare professional.
    • Ensure the vaccine is not expired before use.
    • Use a sterile needle and syringe for each injection to prevent contamination.
    • Dispose of all sharps and medical waste properly.
    • Report any adverse reactions or side effects to your healthcare provider immediately.
    • Keep a record of vaccination dates and doses for future reference.

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