TRIVIDOX 3ML INJ

Cyanocobalamin, Pyridoxine, and Thiamine HCl Injection work through distinct mechanisms to support various physiological processes. Cyanocobalamin, a form of vitamin B12, plays a crucial role in DNA synthesis, red blood cell formation, and the maintenance of the myelin sheath surrounding nerves. It is involved in the methylation of homocysteine to methionine, a process essential for cellular metabolism. Pyridoxine, also known as vitamin B6, functions as a coenzyme in numerous enzymatic reactions, particularly in amino acid metabolism and the synthesis of neurotransmitters like serotonin and norepinephrine. Thiamine HCl, or vitamin B1, is essential for carbohydrate metabolism and the production of ATP, serving as a cofactor for enzymes involved in the Krebs cycle and the pentose phosphate pathway. Together, these vitamins contribute to overall metabolic function, nerve health, and the synthesis of vital compounds in the body.

Cyanocobalamin, Pyridoxin, Thiamine HCL

Vitamin B Complex

Injection

The following are the uses of Cyanocobalamin, Pyridoxin, Thiamine HCL Injection:

• Used for treating Vitamin B12 deficiency, pernicious anemia, and neurological disorders.
• Used for preventing and treating Vitamin B6 deficiencies, particularly in those with malabsorption issues.
• Used for addressing nutritional deficiencies, including in alcoholics and those with dietary restrictions.
• Used for improving nerve function and treating nerve-related symptoms like numbness and tingling.
• Used for boosting energy metabolism and supporting the breakdown of carbohydrates.
• Used for enhancing red blood cell production and preventing anemia.
• Used for promoting healthy skin, hair, and liver function.
• Used for supporting overall growth and development, especially in children.

In the case of an overdose of Cyanocobalamin, Pyridoxine, and Thiamine HCL Injection, the primary concern is the potential for neurological symptoms. Overdose may lead to sensations of numbness, tingling, or burning in the extremities, as well as dizziness and confusion. If an overdose is suspected, immediate medical attention is necessary to manage these symptoms and prevent any long-term neurological complications. Prompt treatment can help mitigate the effects of an overdose.

In the case of a missed dose of Cyanocobalamin, Pyridoxine, and Thiamine HCL Injection, it is important to administer the medication as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to adjust your dosing schedule and ensure you receive the necessary treatment.

To administer Cyanocobalamin, Pyridoxin, Thiamine HCL Injection, prepare the injection by drawing the prescribed amount of medication into a syringe, ensuring it is free from air bubbles, and inject it intramuscularly or subcutaneously at the recommended site, following the dosage instructions provided by your healthcare professional, typically once daily or as directed.

Here are the conditions or situations when Cyanocobalamin, Pyridoxine, and Thiamine HCl Injection should not be used:

• Should not be administered to individuals with a known allergy or hypersensitivity to any of the vitamins • Cyanocobalamin, Pyridoxine, or Thiamine.
• Contraindicated in patients with Leber's disease, a hereditary optic nerve atrophy.
• Not recommended for individuals with anemia that is not caused by vitamin deficiency.
• Should be avoided in patients with a history of blood clots or thrombosis.
• Not suitable for individuals with kidney disease or those undergoing dialysis.
• Should not be used to treat fatigue or weakness without a confirmed vitamin deficiency.
• Contraindicated in patients with a history of allergic reactions to injectable medications.
• Not recommended for individuals with certain metabolic disorders, such as methylmalonic acidemia or transcobalamin deficiency.
• Should be used with caution in patients with cardiovascular disease, as high doses of vitamin B6 (Pyridoxine) may be associated with nerve damage.

The side effects of Cyanocobalamin, Pyridoxin, Thiamine HCL Injection may include:

• Allergic reactions such as hives, itching, or difficulty breathing.
• Swelling of the face, lips, or tongue.
• Redness, pain, or swelling at the injection site.
• Nausea and vomiting.
• Headache and dizziness.
• Nervousness and anxiety.
• Skin rash or itching.
• Diarrhea.

Following are the precautions and warnings for Cyanocobalamin, Pyridoxin, Thiamine HCL Injection:

• Allergic reactions may occur; seek medical attention if you experience symptoms like rash, itching, swelling, or difficulty breathing.
• This medication should be used with caution in patients with kidney or liver disease, as it may require dosage adjustments.
• Do not inject intravenously, as it is intended for intramuscular or deep subcutaneous use only.
• Diabetic patients should be aware that this medication may contain sugar and can affect blood glucose levels.
• Consult a doctor if you have any pre-existing medical conditions or are taking other medications to ensure safe use.
• Inform your healthcare provider if you experience any unusual symptoms or if your condition worsens.
• Store the injection properly and keep out of reach of children and pets.
• Do not use if the solution appears discolored or contains particles.

Following are the drug interactions for Cyanocobalamin, Pyridoxin, Thiamine HCL Injection:

• Concomitant use with alcohol may decrease the absorption of thiamine, leading to reduced effectiveness.
• Concurrent use of chloramphenicol may decrease the effects of cyanocobalamin, requiring close monitoring.
• Pyridoxine may reduce the efficacy of levodopa in Parkinson's disease patients.
• Anticonvulsants like phenytoin and carbamazepine can decrease vitamin B6 levels, necessitating monitoring.
• High doses of pyridoxine may reduce the effectiveness of certain medications, including tetracycline antibiotics.
• Certain medications, such as colchicine and cycloserine, may increase the risk of peripheral neuropathy when used with thiamine.
• Caution is advised when using this combination with drugs that affect the metabolism of vitamins B1, B6, and B12.

Following are the food interactions for Cyanocobalamin, Pyridoxin, Thiamine HCL Injection:

• Alcohol intake should be limited as it can interfere with the absorption of vitamins, particularly thiamine, and may increase the risk of vitamin deficiency.
• Grapefruit and grapefruit juice should be consumed with caution as they can potentially interact with vitamin B12 (Cyanocobalamin) absorption, affecting its bioavailability.
• Vitamin B6 (Pyridoxine) absorption can be reduced by high protein diets, so ensure a balanced diet for optimal absorption.
• Vitamin B12 deficiency is common in vegans and vegetarians, so dietary sources like fortified foods or supplements are crucial.
• Avoid excessive consumption of raw eggs as they contain a protein called avidin, which can bind to biotin (a B-vitamin) and reduce the absorption of other B-vitamins.
• Ensure adequate dietary intake of whole grains, legumes, nuts, and seeds to support vitamin B6 and B1 absorption.
• Avoid excessive consumption of tea and coffee, as tannins can interfere with iron absorption, which is essential for vitamin B absorption.
• Maintain a balanced diet to ensure optimal vitamin absorption and minimize the need for injections.

Cyanocobalamin, Pyridoxin, and Thiamine HCL Injection should be stored and disposed of with utmost care. Store the injection in a cool, dry place, preferably at room temperature, ensuring it is protected from light and moisture. Keep the medication in its original packaging, tightly sealed, to maintain its integrity. Avoid exposure to extreme temperatures, including heat sources and direct sunlight, as they can degrade the injection. Dispose of any unused or expired medication responsibly; do not flush it or pour it down the drain. Contact your pharmacist or healthcare provider for guidance on proper disposal methods. Keep the injection out of children's reach to prevent accidental ingestion.

Following are the quick tips for Cyanocobalamin, Pyridoxine, and Thiamine HCL Injections:

• Administer the injection as directed by your healthcare professional for best results.
• Ensure the injection is prepared and stored as instructed by your pharmacist.
• Inject the medication under proper medical supervision.
• Follow the prescribed dosage and administration schedule for consistent results.
• Report any unusual reactions or side effects to your doctor promptly.
• Do not reuse needles or syringes; dispose of them safely.
• Store the medication as directed, away from children and pets.
• Regularly monitor your health and consult your doctor for any concerns.