Ulcerex (100mg) 60ml Suspension

Cimetidine, the active ingredient in the 100mg syrup/suspension, primarily acts by inhibiting the production of stomach acid. It is a histamine H2-receptor antagonist, meaning it blocks the action of histamine on specific receptors in the stomach known as H2 receptors. Normally, histamine stimulates these receptors, leading to the production of gastric acid. By competitively binding to these receptors, cimetidine prevents histamine from binding, thus reducing the secretion of gastric acid. This mechanism helps in decreasing the acidity of the stomach contents, which can be beneficial in the treatment of conditions like gastroesophageal reflux disease (GERD) and peptic ulcers, where excess stomach acid is a contributing factor.

Cimetidine 100mg

H2-receptor antagonist.

Suspension

The following are the uses of Cimetidine 100mg Syrup/Suspension:

• Used for treating acid reflux and heartburn, providing quick relief.
• Used to heal and prevent stomach and duodenal ulcers.
• Used to manage conditions like Zollinger-Ellison syndrome, reducing excessive acid production.
• Used to relieve symptoms of indigestion and acid regurgitation.
• Used to reduce acid levels in the stomach, aiding in healing.
• Used as a supplementary treatment for GERD (Gastroesophageal Reflux Disease).
• Used to alleviate discomfort caused by excess stomach acid.
• Used to improve overall digestive comfort and well-being.

In the case of an overdose of Cimetidine 100mg Syrup/Suspension, individuals may experience symptoms such as dizziness, confusion, rapid heartbeat, and gastrointestinal issues like nausea, vomiting, or diarrhea. Prompt medical intervention is necessary, as severe cases can lead to more critical complications. The treatment for overdose may involve supportive care, monitoring vital signs, and managing symptoms until the excess medication is cleared from the system. It is important to seek medical advice for any suspected overdose.

In the case of a missed dose of Cimetidine 100mg Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for a missed one, as this may increase the risk of side effects. It is generally recommended to take the medication as prescribed and consult your healthcare provider if you have any concerns about missed doses or adjusting your medication schedule.

To administer Cimetidine 100mg Syrup/Suspension, shake the bottle well, measure the prescribed dose with an accurate measuring device, and take it orally once daily, following the dosage instructions provided by your healthcare professional, regardless of food intake.

Here are the conditions or situations when Cimetidine 100mg Syrup/Suspension should not be used:

• Avoid using Cimetidine if you have a known allergy or hypersensitivity to Cimetidine or other H2-receptor antagonists.
• Do not use this medication if you have a history of acute porphyria, as it can trigger an attack.
• Contraindicated in patients with severe kidney disease or kidney failure, as dosage adjustments are necessary.
• Not recommended for individuals with a history of liver disease or impaired liver function.
• Should not be used in patients with a slow heart rate (bradycardia) or heart block.
• Avoid using Cimetidine if you have a history of lung diseases like chronic obstructive pulmonary disease (COPD) or asthma, as it may worsen breathing.
• Do not administer Cimetidine Syrup/Suspension to infants, especially newborns, due to potential risks.
• Contraindicated in breastfeeding women, as Cimetidine can pass into breast milk.

The side effects of Cimetidine 100mg Syrup/Suspension may include:

• Diarrhea
• Nausea and vomiting
• Dizziness or lightheadedness
• Skin rashes or itching
• Headache
• Confusion or disorientation
• Fatigue and weakness
• Joint pain

Following are the precautions and warnings for Cimetidine 100mg Syrup/Suspension:

• This medication should not be used in patients with a known hypersensitivity or allergy to Cimetidine or any of its excipients.
• Cimetidine may interact with other drugs, so patients should inform their doctor about all medications they are currently taking.
• It should be used with caution in patients with liver or kidney disease, as dosage adjustments may be necessary.
• Avoid alcohol consumption while taking Cimetidine, as it may increase the risk of side effects.
• Patients with a history of gastrointestinal bleeding or other bleeding disorders should use this medication with caution.
• Do not exceed the recommended dosage, as high doses may lead to increased adverse effects.
• Pregnant and breastfeeding women should consult their doctor before using this medication, as the risks and benefits should be carefully considered.
• Store the syrup/suspension at room temperature and keep it out of reach of children.

Following are the drug interactions for Cimetidine 100mg Syrup/Suspension:

• May reduce the elimination of drugs metabolized by the liver, such as diazepam, lidocaine, and phenytoin, leading to increased levels and potential toxicity.
• Can decrease the absorption of certain medications like itraconazole, ketoconazole, and delavirdine, affecting their effectiveness.
• Cimetidine may increase the blood levels of warfarin, potentially enhancing its anticoagulant effect and increasing the risk of bleeding.
• When combined with theophylline, it can lead to elevated theophylline levels, increasing the risk of side effects.
• Antacids containing aluminum or magnesium may reduce the absorption of Cimetidine, thus reducing its effectiveness.
• May interact with clopidogrel, potentially reducing its antiplatelet effect.
• Cimetidine may decrease the effectiveness of certain immunosuppressants like tacrolimus and cyclosporine.

Following are the food interactions for Cimetidine 100mg Syrup/Suspension:

• Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of side effects and may enhance the sedative effects of Cimetidine.
• Grapefruit and grapefruit juice should be consumed with caution. These can increase the levels of Cimetidine in the body, potentially leading to an increased risk of side effects.
• Caffeine-containing beverages such as coffee, tea, and energy drinks may interfere with the effectiveness of Cimetidine, as it can stimulate gastric acid secretion.
• Foods rich in tyramine, such as aged cheeses, cured meats, and certain types of beer, should be avoided. Cimetidine can potentially interact with tyramine, leading to a sudden increase in blood pressure.
• Avoid high-fat meals, as they may decrease the absorption of Cimetidine, making it less effective.
• Do not consume salt substitutes or potassium-rich foods without medical advice while taking Cimetidine, as it can lead to a potassium imbalance.
• Avoid eating large meals close to bedtime when taking Cimetidine, as it may cause discomfort and affect the medication's effectiveness.
• Always follow the advice of your healthcare provider regarding dietary restrictions and recommendations while using Cimetidine.

Cimetidine 100mg Syrup/Suspension should be stored with care, ensuring a cool and dry environment, ideally at room temperature, shielded from direct sunlight and moisture. Keep the medication securely sealed in its original packaging to maintain its integrity and prevent contamination. Avoid bathroom storage or proximity to heat-emitting appliances like stoves or radiators, as temperature fluctuations can compromise the medicine's efficacy. Always verify the expiration date, and when disposing of any unused or expired syrup, refrain from flushing or pouring it down the drain. Consult your pharmacist or healthcare provider for environmentally friendly disposal options. Lastly, ensure the medication is stored in a secure location, out of reach of children, to prevent accidental consumption.

Following are the quick tips for Cimetidine 100mg Syrup/Suspension:

• Consult your doctor for the right dosage and duration of treatment.
• Administer the prescribed amount using the measuring cup provided.
• Give the syrup directly into the mouth or mix with a small amount of water/juice.
• If using a feeding tube, flush the tube before and after administering the medication.
• Avoid taking antacids within 1 hour of taking this medicine.
• Store the syrup in a cool, dry place, away from direct sunlight.
• Do not use if the syrup changes color or develops an unpleasant odor.