Unilox (500mg) 10 Capsules

Levofloxacin 500mg capsules exhibit their antibacterial effect through potent inhibition of bacterial DNA gyrase and topoisomerase IV, essential enzymes responsible for DNA replication and cell division in bacteria. By binding to these enzymes, levofloxacin prevents the relaxation of supercoiled DNA, leading to the disruption of DNA synthesis and ultimately resulting in bacterial cell death. This mechanism specifically targets bacterial topoisomerases, which are distinct from mammalian topoisomerases, contributing to the selective antibacterial activity of levofloxacin.

Levofloxacin 500mg

Fluoroquinolone antibiotic.

Capsule

The following are the uses of Levofloxacin 500mg Capsule:

• Used for treating bacterial infections, including respiratory, skin, and urinary tract infections.
• Used for pneumonia, effectively targeting the bacteria causing the infection.
• Used for chronic bronchitis flare-ups, helping to control bacterial exacerbations.
• Used in the treatment of acute sinus infections, providing relief from symptoms.
• Used to manage certain types of kidney and bladder infections, eliminating the responsible bacteria.
• Used for skin structure infections, aiding in the healing process.
• Used as an alternative therapy for individuals with specific bacterial infections who cannot use other antibiotics.
• Used to prevent and treat anthrax infection, offering protection against this rare but serious condition.

In the case of an overdose of Levofloxacin 500mg capsules, several symptoms may occur, including nausea, vomiting, and dizziness. More severe cases can lead to seizures, difficulty breathing, and changes in blood pressure or heart rate. Prompt medical intervention is necessary to manage these symptoms effectively. Patients should be closely monitored, and treatment may involve gastric lavage, administration of activated charcoal, and supportive care to address any cardiovascular or respiratory complications.

In the case of a missed dose of Levofloxacin 500mg Capsule, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to adjust your medication schedule and ensure the best treatment outcome. It is generally recommended to take the medication at evenly spaced intervals to maintain an effective level in your system.

To take Levofloxacin 500mg Capsule, swallow the capsule whole with a full glass of water, preferably at the same time each day, without crushing or chewing, and complete the full course as prescribed by your healthcare provider.

Here are the conditions or situations when Levofloxacin 500mg Capsule should not be used:

• Do not take if you have a known allergy to Levofloxacin or any other quinolone antibiotics.
• Contraindicated in patients with a history of myasthenia gravis as it can worsen muscle weakness.
• Avoid if you have a history of tendon disorders or tendon rupture after taking quinolones.
• Not recommended for individuals with epilepsy or other seizure disorders.
• Do not use in patients with a slow heart rate or heart rhythm disorders.
• Contraindicated in patients with low potassium or magnesium levels in the blood.
• Should not be used in children, adolescents, or young adults due to the risk of bone and joint disorders.
• Avoid in patients with kidney disease or those on dialysis.
• Do not take if you have a history of liver disease or impaired liver function.
• Contraindicated in patients with central nervous system disorders such as psychosis or severe anxiety.

The side effects of Levofloxacin 500mg Capsule may include:

• Nausea and vomiting
• Diarrhea
• Headache
• Dizziness
• Insomnia (difficulty sleeping)
• Skin rash or itching
• Joint or muscle pain
• Increased sensitivity to sunlight

Following are the precautions and warnings for Levofloxacin 500mg Capsule:

• Do not take this medication if you have a known allergy to Levofloxacin or other quinolone antibiotics.
• This medication can cause serious tendon damage, especially in individuals over 60 years old, those taking corticosteroids, and those with kidney, heart, or lung transplants. Discontinue use and seek medical attention if you experience tendon pain or swelling.
• Levofloxacin can increase the risk of seizures; use with caution in patients with a history of seizures or conditions that lower the seizure threshold.
• May cause dizziness and lightheadedness, especially in elderly patients. Avoid driving or operating machinery until you know how this medication affects you.
• Patients with a history of myasthenia gravis should be cautious as Levofloxacin may worsen muscle weakness.
• Inform your doctor if you have kidney or liver disease, as dosage adjustments may be necessary.
• Avoid excessive sunlight or UV light exposure while taking this medication, as it can increase sensitivity to sunlight.
• Pregnant and breastfeeding women should consult their healthcare provider before taking Levofloxacin, as it may cause harm to the fetus or infant.

Following are the drug interactions for Levofloxacin 500mg Capsule:

• Antacids containing aluminum, magnesium, or calcium can reduce the absorption of Levofloxacin, so they should be taken at least 2 hours apart.
• Theophylline levels may increase when used with Levofloxacin, requiring monitoring and dose adjustments.
• Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen may increase the risk of central nervous system stimulation and seizures.
• Probenecid can increase Levofloxacin concentrations, potentially leading to increased side effects.
• Sucralfate may reduce the absorption of Levofloxacin; they should be taken at least 2 hours apart.
• Levofloxacin may enhance the effects of warfarin and other anticoagulants, requiring close monitoring of coagulation parameters.
• The risk of tendon damage or rupture may increase when used with corticosteroids.
• The effectiveness of live attenuated vaccines (e.g., typhoid vaccine) may be reduced during and shortly after Levofloxacin treatment.

Following are the food interactions for Levofloxacin 500mg Capsule:

• Avoid consuming dairy products like milk, yogurt, or cheese with Levofloxacin, as calcium can interfere with the absorption of the medication, reducing its effectiveness.
• Iron-rich foods like red meat, spinach, and beans should be consumed at least 2 hours before or after taking Levofloxacin, as iron can decrease its absorption.
• Antacids containing magnesium or aluminum should be avoided as they can reduce the absorption of Levofloxacin if taken simultaneously.
• Vitamin and mineral supplements, especially those containing calcium, magnesium, or iron, should be taken at different times to ensure proper absorption of Levofloxacin.
• Grapefruit and grapefruit juice should be avoided as they can increase the levels of Levofloxacin in the blood, leading to potential side effects.
• Avoid alcohol consumption as it may increase the risk of liver problems and nervous system side effects when combined with Levofloxacin.
• Caffeine intake should be monitored as Levofloxacin may increase its concentration in the body, potentially causing jitteriness and sleep disturbances.
• Always ensure you stay well-hydrated when taking Levofloxacin to aid in the medication's effectiveness and reduce the risk of side effects.

Levofloxacin 500mg Capsules should be stored in a cool and dry place, preferably at room temperature (68°F to 77°F). Keep the capsules in their original packaging or a tightly sealed container to protect them from moisture and light. It is crucial not to store them in the bathroom or kitchen, as these areas may have high humidity or temperature fluctuations. When disposing of unused or expired capsules, do not throw them in the trash or flush them down the toilet. Instead, follow local guidelines for medication disposal, which may include returning them to a pharmacy or a designated collection point for safe disposal. Always keep medications securely locked away from children and pets to prevent accidental consumption. Proper storage and disposal practices are essential to maintain the effectiveness of the medication and ensure the safety of others.

Following are the quick tips for Levofloxacin 500mg Capsule:

• Take the capsule as directed by your doctor, typically once or twice daily.
• Swallow the capsule whole with a full glass of water; do not crush or chew.
• Take it at the same time each day to maintain consistent medication levels.
• Ensure you complete the full prescribed course, even if you feel better early on.
• Avoid excessive sunlight and use sunscreen when outdoors during treatment.
• Inform your doctor if you have a history of tendon disorders or myasthenia gravis.
• Store the capsules at room temperature, away from moisture and light.