Uripas (200mg) 30 Tablets

Doxazosin, a medication primarily used to treat hypertension and benign prostatic hyperplasia (BPH), operates through a specific mechanism of action. It belongs to a class of drugs known as alpha-1 adrenergic blockers, which means it works by blocking the alpha-1 adrenergic receptors in various parts of the body. When Doxazosin binds to these receptors, it causes the smooth muscles in the walls of blood vessels to relax, leading to vasodilation. This relaxation reduces peripheral vascular resistance, resulting in decreased blood pressure. Additionally, in the context of BPH, Doxazosin's action relaxes the smooth muscle in the prostate and bladder neck, easing urinary symptoms by improving urine flow and reducing bladder outlet obstruction.

Doxazosin 200mg

Alpha-1 adrenergic blocker.

Tablet

The following are the uses of Doxazosin 200mg Tablet:

• Used for treating high blood pressure, helping to lower and control hypertension.
• Used for managing and alleviating symptoms of benign prostatic hyperplasia (BPH), reducing urinary issues associated with an enlarged prostate.
• Used for improving urinary flow and reducing discomfort during urination in patients with prostate issues.
• Used for managing and preventing urinary tract infections by improving bladder emptying.
• Used for relieving pelvic pain and discomfort caused by prostate problems.
• Used for improving overall quality of life in patients with BPH, enabling better daily functioning.
• Used for long-term management of prostate-related urinary symptoms, offering sustained relief.

In the case of an overdose of Doxazosin 200mg Tablets, it is important to recognize the potential severity of the situation. Symptoms may include dizziness, fainting, and a sudden drop in blood pressure. Prompt action is required, and medical assistance should be sought immediately. Do not hesitate to contact emergency services or seek professional medical advice, as they can provide the necessary guidance and support to manage the overdose effectively. This is crucial for ensuring the best possible outcome and preventing potential complications.

In the case of a missed dose of Doxazosin 200mg Tablet, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen. It is always best to consult your doctor or pharmacist for advice on managing missed doses.

To take Doxazosin 200mg Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, typically once daily.

Following are the conditions when Doxazosin 200mg Tablet should not be used:

• Avoid taking this medication if you have a known allergy to Doxazosin or other similar medications.
• Do not use if you have a history of orthostatic hypotension (sudden drop in blood pressure upon standing).
• Contraindicated in individuals with severe liver impairment.
• Should not be used in patients with severe kidney disease.
• Not recommended for individuals with a history of heart disease, such as angina, recent heart attack, or severe heart failure.
• Avoid if you have a rare heart condition called aortic stenosis.
• Do not use if you have ever had an allergic reaction to similar drugs (alpha-blockers).
• Not suitable for individuals with a history of multiple system atrophy, a rare neurological disorder.

The side effects of Doxazosin 200mg Tablet may include:

• Dizziness or lightheadedness, especially when standing up or sitting up suddenly
• Fatigue or drowsiness
• Headaches
• Nausea and vomiting
• Weakness or tiredness
• Skin rashes or itching
• Difficulty breathing or shortness of breath
• Swelling of the hands, feet, or ankles

Following are the precautions and warnings for Doxazosin 200mg Tablet:

• Not recommended for individuals with known allergies or sensitivities to Doxazosin or similar medications.
• Patients with a history of orthostatic hypotension should exercise caution, as Doxazosin can cause a drop in blood pressure upon standing.
• It may cause dizziness and lightheadedness, so patients should be cautious when performing activities that require alertness, such as driving or operating heavy machinery.
• Elderly patients may be more sensitive to the side effects, particularly dizziness and hypotension.
• Use with caution in patients with liver or kidney disease, as dosage adjustments might be necessary.
• Not recommended for children and adolescents under 18 years of age unless prescribed by a doctor.
• Pregnant and breastfeeding women should consult their healthcare professional before taking this medication as it may have potential risks.

Following are the drug interactions for Doxazosin 200mg Tablet:

• Medications metabolized by CYP3A4 enzyme, such as ketoconazole, erythromycin, and ritonavir, can increase the levels of Doxazosin, potentially leading to enhanced side effects.
• Doxazosin may cause an additive blood pressure-lowering effect when used with other antihypertensive drugs, requiring close monitoring.
• Alpha-blockers like prazosin and tamsulosin may have an additive effect with Doxazosin, increasing the risk of orthostatic hypotension.
• The effectiveness of Doxazosin may be reduced when used with NSAIDs like ibuprofen, as these drugs can inhibit its antihypertensive effects.
• Medications that significantly lower blood pressure, such as nitrates, can increase the hypotensive effects of Doxazosin.
• Doxazosin can interact with phosphodiesterase-5 (PDE-5) inhibitors like sildenafil, tadalafil, and vardenafil, potentially causing a sudden drop in blood pressure.
• Drugs affecting the renin-angiotensin system, including ACE inhibitors and angiotensin receptor blockers, may have additive effects on blood pressure when used with Doxazosin.

Following are the food interactions for Doxazosin 200mg Tablet:

• Grapefruit and grapefruit juice consumption should be limited as they can increase the blood levels of Doxazosin, potentially leading to an increased risk of side effects, especially low blood pressure.
• Alcohol may cause excessive dizziness and drowsiness when combined with Doxazosin, so it's advisable to limit or avoid alcohol intake.
• High-sodium foods should be consumed in moderation as Doxazosin is a blood pressure-lowering medication, and high sodium intake can counteract its effectiveness.
• Foods rich in potassium, like bananas and oranges, should be consumed with caution as Doxazosin may increase potassium levels, and excessive intake might lead to irregular heart rhythms.
• Avoid or limit caffeine intake as it can increase blood pressure, working against the effects of Doxazosin.
• Consume a balanced diet to maintain overall health, as Doxazosin may be a long-term medication for some conditions.
• Always follow the dietary advice provided by your healthcare professional, especially if you have specific dietary restrictions or health conditions.

Doxazosin 200mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. Avoid storing it in bathrooms or near heat-emitting appliances as temperature fluctuations can impact the medication's effectiveness. Proper disposal is crucial; do not flush or pour the medication down the drain. Consult your pharmacist or healthcare provider for appropriate disposal methods to protect the environment. Keep the medication away from children to prevent accidental ingestion.

Following are the quick tips for Doxazosin 200mg Tablet:

• Take the tablet as directed by your doctor, typically once daily.
• Consume the tablet whole with a full glass of water, do not crush or chew.
• Maintain a consistent daily routine for taking the medication.
• Avoid missing doses; take it at the same time each day.
• If you experience dizziness, especially when standing up, rise slowly to prevent falls.
• Inform your doctor about all medications you are taking to avoid interactions.
• Store the tablets at room temperature, away from moisture and light.