Uristat (40mg) 20 Tablets

Uristat (40mg) 20 Tablets

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  • Manufacturer Cell Laboratories (Pvt.) Ltd.
  • Generic Name Febuxostat

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Storage/Disposal
  • Description

    Febuxostat is a unique drug that acts as a non-purine specific inhibitor of xanthine oxidase, the enzyme responsible for breaking down xanthine and hypoxanthine into uric acid. By inhibiting xanthine oxidase, Febuxostat reduces the formation of uric acid and aids in the relief of hyperuricemia and urate crystal deposition in tissues. Through this mechanism of action, Febuxostat is used in the treatment of gout, a condition caused by the buildup of uric acid crystals in the joints. This medication is typically prescribed to individuals who have not responded to or cannot take allopurinol, or in those who have an intolerance to uric acid crystals deposits in the kidneys causing recurrent or refractory uric acid nephropathy. When administered to those with kidney disease, Febuxostat is effective in both reducing these types of stones and preventing their formation.

  • Ingredients

    Febuxostat
  • Drug Class

    Xanthine Oxidase Inhibitor

  • Dosage Form

    Tablet
  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Treatment of chronic hyperuricemia in patients with gout.
    • Relief of gout attacks.
    • Reduction of tophi (deposit of uric acid crystals in the tissue) in patients with gout.
    • Management of urate levels in individuals with gout.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Gout- Take 40 mg once a day, preferably with food.
    • Kidney Disease- Take 40 mg once a day, preferably with food.
    • Prevent Gout Attacks- Take 40 mg once a day, preferably with food.
    • Licopidine with Febuxostat- Take 40 mg once a day, preferably with food
  • In case of Overdose

    An Febuxostat overdose requires immediate attention from emergency medical services to provide appropriate treatment. Supportive care is a common treatment technique, involving the monitoring of the patient's vital signs, managing any complications, and reversing the effects of the overdose. In more severe cases, induced vomiting and the administration of digestion-promoting medications help flush the drugs from the body. Intensive care and monitoring may be required depending on the severity of symptoms and complications. Timely and appropriate medical care has a positive prognosis for recovery, however, this depends on the individual's health condition and the severity of the overdose. It is best to consult a medical professional for guidance and treatment as they will provide personalized advice based on an individual's unique circumstances.

  • Missed Dose

    If you miss a dose of Febuxostat, it is important to take it as soon as you remember. However, if it is almost time for your next scheduled dose, it is recommended to skip the missed dose and continue with your regular dosage schedule. Doubling up on doses of Febuxostat is not advised as it can lead to an increased risk of side effects. If you are unsure about what to do or if you have any concerns about missing a dose, it is best to speak with your physician or a pharmacist for guidance on how to move forward. They may provide you with advice tailored to your specific situation.

  • How To Use

    Before starting Febuxostat, it is important to read the medication guide provided by your pharmacist. This medication is typically taken once daily, with or without food, but it is crucial to choose one method and stick to it. Instead of crushing, breaking, or chewing the tablet, it is intended that you swallow it whole. Depending on your condition, your doctor may start you on a lower dose and gradually increase it to reduce the risk of side effects. It is essential to follow the dosage instructions provided by your doctor or pharmacist. Even if you feel well, continue to take this medication as directed by your doctor. If you miss a dose, take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and follow the regular dosing schedule. Do not double the dose to make up for a missed one.This medication may cause increased liver enzymes and gout flares in some people. It is advised to consult your doctor or pharmacist for more details. It is important to inform your doctor about all the medicines you are currently taking, including any vitamins, herbal supplements, and over-the-counter medicines, as there may be potential drug interactions resulting in serious side effects. Ensure you follow the instructions provided with your medication and consult a healthcare professional if you have any questions or concerns about your treatment.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • Febuxostat is a medication that is normally taken once daily at a dose of 80mg to mitigate uric acid levels in the blood
    • It is important to follow your medical professional's directions for use and to consult them for any adjustments to dosage
    • Febuxostat 40mg should not be taken by individuals who have a hypersensitivity to the active substance febuxostat or to any of the excipients in the medicinal product
    • Symptoms of hypersensitivity may include hives, difficulty breathing, and swelling of the face, throat, or mouth
    • You have severe kidney disease or an estimated glomerular filtration rate (eGFR) of less than 30 mL/min, which could lead to increased concentrations of febuxostat in the blood. This may increase the risk of adverse reactions
    • You have a history of cancer, especially lymphoid malignancies (tumors of the lymph system), since febuxostat may cause serious infections or reoccurrence of cancer
    • You have a uric acid level below 6 mg/dL or 360 µmol/L in the blood. Febuxostat reduces uric acid levels in the blood, so if your uric acid levels are already low this could lead to severe and sudden decreases in uric acid levels that may cause gout flares
    • You are taking certain medications for infections, osteoporosis, or kidney dysfunction. Interactions can lead to increased febuxostat concentrations in the blood, which may increase the risk of adverse reactions. These medications include acetylsalicylic acid (ASA), azathioprine, corticosteroids, gold salts, immunosuppressants, lithium, penicillin, phenylbutazone, procainamide, quinolones, sulfinpyrazone, and thioguanine
    • You have liver disease or impaired liver function. Liver disease or reduced liver function can lead to an increase
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Gastrointestinal issues
    • Allergic reactions
    • Risk of infections
    • Respiratory symptoms
    • Bone or muscle pain
    • Weight loss
    • Sleep disturbances or fatigue
    • Headache
    • Diarrhea or constipation
  • Storage/Disposal

    Febuxostat is a medication that helps to relieve gout symptoms, which is a type of arthritis caused by the accumulation of uric acid in the joints. It is essential to follow the recommended storage instructions to ensure that the medication remains effective and safe to use.The Febuxostat tablets should be stored at room temperature, between 59°F and 86° Fahrenheit (15°C and 30°C). It is crucial to keep the medication away from heat, moisture, and light. For this reason, you should not store it in the bathroom, as the humidity can impact the medication's effectiveness. Ensure that you keep it in a cool, dry place, such as a cupboard or drawer. To prevent any accidents or unwanted exposure, make sure to keep Febuxostat out of reach of children and pets. Store it in a secure location, like a locked cabinet or box, to prevent unauthorized access.

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