Uro-K (10mEq) 30 Tablets

Potassium citrate tablets work primarily by increasing the alkalinity of urine, which is their mechanism of action. When taken orally, potassium citrate dissociates into potassium and citrate ions in the body. Citrate is the key player here; it is metabolized in the body to form bicarbonate, which raises the pH of the urine, making it more alkaline. This increased alkalinity helps to dissolve and prevent the formation of certain types of kidney stones, particularly those composed of uric acid or cystine. By creating a less acidic environment in the urine, potassium citrate discourages the crystallization of these substances, thereby reducing the risk of stone formation and promoting the dissolution of existing stones.

Alkali-forming, Potassium-sparing

Tablet

The following are the uses of Potassium Citrate Tablet:

• Used for preventing kidney stones by controlling the levels of acid in the urine
• Used for treating gout, a form of arthritis caused by high uric acid levels
• Used to manage metabolic acidosis, a condition where the blood becomes too acidic
• Used to reduce the risk of uric acid kidney stones in people with high uric acid levels
• Used to alleviate the symptoms of cystinuria, a disorder causing cystine stones
• Used to support the treatment of renal tubular acidosis, a kidney disorder
• Used for maintaining a healthy pH balance in the body

In the case of an overdose of Potassium Citrate Tablets, individuals may experience gastrointestinal symptoms such as nausea, vomiting, and diarrhea. More severe effects can include muscle weakness, irregular heartbeat, and even cardiac arrest. It is crucial to seek medical assistance promptly, as the healthcare provider will likely recommend gastric lavage or administer intravenous fluids to stabilize the patient and manage any cardiac complications that may arise from the excessive potassium levels in the body.

In the case of a missed dose of Potassium Citrate Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen. It is advisable to set reminders or use a pill organizer to help you stay on track with your medication schedule.

To take Potassium Citrate Tablets, swallow the tablet whole with a full glass of water, ensuring you follow the prescribed dosage as directed by your healthcare provider, typically taken 1 to 4 times a day or as recommended.

Following are the conditions when Potassium Citrate Tablet should not be used:

• Avoid use in patients with severe kidney disease or impaired kidney function.
• Should not be used in individuals with a known allergy to potassium citrate or any of its inactive ingredients.
• Contraindicated in patients with severe gastrointestinal disorders, such as colitis or ileus.
• Not suitable for individuals with uncontrolled high blood pressure.
• Should not be used in patients with conditions that cause low levels of potassium in the blood (hypokalemia).
• Avoid use in patients with urinary tract infections until the infection is treated and resolved.
• Contraindicated in individuals with conditions that cause high levels of potassium in the blood (hyperkalemia).
• Not recommended for patients with certain types of kidney stones, such as uric acid or cystine stones.

The side effects of Potassium Citrate Tablet may include:

• Nausea and vomiting
• Stomach pain or discomfort
• Diarrhea
• Gas or bloating
• Confusion or mental changes
• Unusual tiredness or weakness
• Muscle cramps or twitching
• Irregular heartbeat

Here are the precautions and warnings for Potassium Citrate Tablet:

• Not recommended for individuals with a known allergy to potassium citrate or any of its ingredients.
• Patients with kidney problems should exercise caution, as dosage adjustments might be necessary for those with renal impairment.
• Those with a history of gastrointestinal issues like stomach ulcers or intestinal blockage should use with caution.
• It may cause stomach irritation; taking the medication with food or milk can help reduce this effect.
• Patients with heart disease or those taking cardiac medications should be monitored for potential electrolyte imbalances.
• Elderly individuals may be more susceptible to side effects, particularly gastrointestinal issues.
• Consult a healthcare professional if you are pregnant, breastfeeding, or planning to become pregnant to ensure safe use.

Following are the drug interactions for Potassium Citrate Tablet:

• It can interact with ACE inhibitors (e.g., enalapril, lisinopril) and increase the risk of hyperkalemia, requiring close monitoring of potassium levels.
• Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen may reduce the effects of Potassium Citrate, as they can decrease potassium levels.
• The use of potassium-sparing diuretics (e.g., spironolactone, triamterene) alongside Potassium Citrate may lead to elevated potassium levels in the blood.
• Potassium Citrate can decrease the absorption of certain antibiotics, such as tetracyclines and fluoroquinolones, reducing their effectiveness.
• Angiotensin II receptor blockers (ARBs) like losartan or valsartan may require careful monitoring when used with Potassium Citrate due to potential hyperkalemia.
• Combining Potassium Citrate with beta-blockers (e.g., metoprolol, propranolol) may necessitate regular potassium level checks.
• It may interact with certain diabetes medications, including insulin and sulfonylureas, potentially causing hypoglycemia or hyperkalemia.

Following are the food interactions for Potassium Citrate Tablets:

• Citrus fruits like oranges, lemons, and grapefruits can interfere with potassium absorption, so it's best to avoid consuming them simultaneously as the medication.
• High-sodium foods such as processed snacks, canned soups, and fast food should be limited as they can reduce the effectiveness of potassium citrate.
• Consuming a diet rich in potassium-rich foods like bananas, sweet potatoes, and spinach can help maintain potassium levels and potentially reduce the dosage required.
• Avoid excessive consumption of dairy products as they can contain high levels of calcium, which may interact with potassium citrate.
• Limit caffeine intake from coffee, tea, and energy drinks as it can increase urinary excretion of potassium.
• Alcohol may decrease the effectiveness of potassium citrate and increase the risk of side effects, so it's best to minimize or avoid it during treatment.
• Stay well-hydrated by drinking plenty of water to support the kidney's function and maintain electrolyte balance.
• Follow a balanced diet as recommended by your healthcare provider to ensure optimal medication effectiveness.

Potassium Citrate Tablets should be stored in a cool and dry environment, preferably at room temperature, ensuring protection from light and moisture. The original packaging should be tightly sealed to maintain the tablets' integrity and prevent exposure to humidity. It's crucial not to store the medication in the bathroom or near heat-emitting appliances to safeguard against temperature fluctuations that could impact its effectiveness. Always adhere to the expiration date on the packaging, and for the safe disposal of unused or expired tablets, consult a pharmacist or healthcare professional for guidance, avoiding improper methods like flushing or pouring down the drain. Keep the medication securely stored, out of children's reach, to prevent accidental consumption.

Following are the quick tips for Potassium Citrate Tablet:

• Always take the tablets as directed by your doctor or pharmacist.
• Swallow the tablets whole with a full glass of water, do not crush or chew.
• Take with food to minimize stomach irritation.
• Avoid taking antacids or other medications containing aluminium, magnesium, or calcium within 2 hours of this medicine.
• Maintain a consistent fluid intake as advised by your healthcare provider.
• Inform your doctor if you have a history of kidney stones or any kidney-related issues.
• Regularly monitor your potassium levels as directed by your healthcare professional.