UTINORMA TAB

Cranberry extract tablets work primarily by inhibiting the adhesion of certain bacteria, particularly *Escherichia coli* (*E. coli*), to the urinary tract walls. The active compounds in cranberry extract, such as proanthocyanidins (PACs), interact with the bacterial fimbriae, which are hair-like structures used by bacteria to attach to the urinary tract epithelium. By binding to these fimbriae, cranberry extract prevents *E. coli* and other bacteria from adhering to the urinary tract cells, thus reducing the likelihood of bacterial colonization and subsequent infection. This mechanism helps to flush out potential pathogens from the urinary system, promoting urinary tract health and reducing the risk of urinary tract infections (UTIs).

Cranberry Extract

Antimicrobial supplement

Tablet

The following are the uses of Cranberry Extract Tablet:

• Used for preventing and treating urinary tract infections (UTIs) due to its ability to inhibit bacterial growth.
• Used for managing and reducing the symptoms of bladder inflammation and infection.
• Used for supporting kidney health and promoting optimal urinary function.
• Used for its antioxidant properties, which may help reduce the risk of certain cancers and cardiovascular diseases.
• Used for managing oral health, as it may inhibit the formation of dental plaque and prevent gum disease.
• Used for its potential benefits in gastrointestinal health, aiding in digestion and maintaining a healthy gut.
• Used for supporting the immune system due to its high vitamin C content.
• Used for promoting overall urinary tract wellness and reducing the frequency of UTIs in susceptible individuals.

In the case of an overdose of Cranberry Extract Tablets, it is important to remain calm and seek medical advice promptly. While cranberry extract is generally safe, excessive consumption may lead to gastrointestinal discomfort, such as nausea, vomiting, or diarrhea. If symptoms persist or worsen, contact a healthcare professional or a poison control center for guidance on appropriate treatment and management. Quick action can help ensure a positive outcome.

In the case of a missed dose of Cranberry Extract Tablet, it is important to take the dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication routine. It is also advisable to consult your healthcare provider if you have concerns or if you miss multiple doses.

To take the Cranberry Extract Tablet, simply swallow the tablet with a glass of water, preferably during a meal or as directed by your healthcare professional, following the recommended dosage instructions provided on the product packaging or as prescribed by your doctor.

Following are the conditions when Cranberry Extract Tablet should not be used:

• Avoid use if you have a known allergy or sensitivity to cranberries, or any other berry fruits from the Ericaceae family.
• Do not take if you are scheduled for surgery or have a bleeding disorder, as it may affect blood clotting.
• Not suitable for individuals with kidney stones or a history of frequent kidney stone formation.
• Avoid use if you are taking blood-thinning medications, as it may increase the risk of bleeding.
• Contraindicated in individuals with low blood pressure, as it may lower blood pressure further.
• Do not use if you are pregnant or breastfeeding, as the safety of cranberry extract in these populations is not well established.
• Discontinue use if you experience any adverse reactions such as nausea, vomiting, diarrhea, or abdominal pain.

The side effects of Cranberry Extract Tablet may include:

• Upset stomach or nausea
• Diarrhea
• Abdominal pain or cramps
• Bladder irritation
• Kidney stones (with excessive use)
• Allergic reactions (such as rash, itching, or swelling)
• Increased risk of bleeding (especially with anticoagulant medications)
• Gastrointestinal discomfort

Following are the precautions and warnings for Cranberry Extract Tablets:

• Not suitable for individuals with known allergies to cranberries or any other ingredients in the tablet.
• Those with a history of kidney stones should exercise caution, as cranberry extract may increase the risk of stone formation.
• May interact with certain medications, especially blood-thinning medications, so consult a healthcare professional before use.
• Not recommended for individuals with a history of kidney or liver disease without medical advice.
• Do not exceed the recommended dosage, as excessive consumption may lead to gastrointestinal issues.
• Pregnant and breastfeeding women should consult their doctor before taking these tablets, as the effects on the fetus and infant are not fully established.
• Discontinue use and seek medical attention if any adverse reactions or side effects occur.

Following are the drug interactions for Cranberry Extract Tablet:

• Cranberry extract may decrease the effectiveness of medications metabolized by the liver, such as warfarin, leading to reduced anticoagulant effects.
• It can increase the risk of bleeding when combined with antiplatelet drugs like clopidogrel.
• May interact with certain antibiotics, including ciprofloxacin and nitrofurantoin, potentially affecting their absorption and efficacy.
• Potential interaction with medications that affect urine pH, such as acetazolamide, which may alter the urinary environment.
• Cranberry extract may enhance the effects of drugs that lower blood sugar, such as insulin or metformin, leading to hypoglycemia.
• Can increase the risk of side effects when taken with medications that affect the central nervous system, including antidepressants and sedatives.
• Interaction with drugs that are highly protein-bound, such as warfarin, may lead to altered drug distribution and potential toxicity.

Following are the food interactions for Cranberry Extract Tablets:

• Avoid excessive consumption of cranberry-based products like juices, sauces, or other foods, as they can lead to an increased intake of oxalates, potentially causing kidney-related issues.
• Limit the intake of foods rich in vitamin K, such as leafy green vegetables, as cranberry extract may interfere with blood-clotting mechanisms.
• Reduce the consumption of foods high in sugar, as cranberry extract may impact blood sugar levels.
• Alcohol may decrease the effectiveness of cranberry extract, so it's advisable to limit alcohol intake.
• Avoid taking the tablets with dairy products, as calcium can hinder the absorption of cranberry's active compounds.
• Grapefruit and its juice should be consumed in moderation, as they can alter the metabolism of various compounds in the extract.
• Consuming fiber-rich foods alongside the tablets can enhance the beneficial effects of cranberry extract on digestive health.

Cranberry Extract Tablets should be stored in a cool and dry environment, preferably at room temperature, ensuring protection from direct sunlight and moisture. It is crucial to keep the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. Avoid exposing the tablets to heat sources like radiators or ovens, as temperature fluctuations can impact their effectiveness. Regularly check the expiration date, and if the tablets are past their prime, dispose of them responsibly. Never flush or pour them down the drain; instead, seek advice from a pharmacist or healthcare professional for appropriate disposal methods. Additionally, keep the tablets out of children's reach to prevent accidental consumption.

Following are the quick tips for Cranberry Extract Tablets:

• Take the tablets as directed on the packaging or as advised by your healthcare professional.
• Ensure you read and understand the instructions before use.
• Swallow the tablets whole with a full glass of water, preferably with a meal.
• Consider taking the tablets with food to minimize potential stomach irritation.
• Do not crush or chew the tablets unless instructed otherwise.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Consult your doctor if you have any pre-existing medical conditions or are taking other medications.